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Biomedical subjects

H Aram

Publications and source records attributed to H Aram.

15 recordsLinked to original sources
PubMed1987

Treatment of female androgenetic alopecia with cimetidine.

Ten white women with moderate to severe androgenetic alopecia were treated with cimetidine 300 mg by mouth five times a day. Duration of therapy ranged from 1.5-9 months, with a median of 5 months. Seven patients (70%) showed good to excellent regrowth of hair. No major side effects were noted. The patients were followed up for 5 months. Cimetidine presumably has the ability to block androgen action. Cimetidine is not a first-line drug for the treatment of androgenetic alopecia in women and should be used only in selected cases.

Adult↗
PubMed1987

Ultrasound-induced hyperthermia in the treatment of cutaneous leishmaniasis.

Local hyperthermia induced by ultrasound was delivered two or three times weekly to twenty-eight lesions of acute cutaneous leishmaniasis in eighteen patients. Twenty-two lesions (78.5 percent) in thirteen patients resolved completely five to ten weeks after the start of treatment. Our results are explained by the thermosensitivity of the parasite and its inability to survive at supranormal temperatures. Ultrasound hyperthermia was tolerated by most of the patients. The results of this study indicate that topical heat is safe and effective for the treatment of patients with acute cutaneous leishmaniasis.

Adolescent↗
PubMed1986

Cryotherapy in acute cutaneous leishmaniasis.

Fourteen patients with acute cutaneous leishmaniasis entered a study testing the efficacy of liquid nitrogen. All lesions were cured clinically and protozoologically within 3-8 weeks, without noticeable scarring. The patients did not experience adverse side effects, and there was no relapse 4 months after cessation of therapy. The results of this study indicate that cryotherapy is a safe and effective method for treating cutaneous leishmaniasis.

Acute Disease↗
PubMed1986

Recurrent cutaneous leishmaniasis: successful treatment with sodium antimony gluconate.

The case of a 15-year-old boy with recurrent cutaneous leishmaniasis is reported. Species identification was based on results of serotyping and isoenzyme analysis. The patient did not respond to rifampin combined with isoniazid or to ketoconazole. Subsequent therapy with systemic sodium antimony gluconate resulted in complete regression of the lesions.

Adolescent↗
PubMed1985

Palmoplantar hyperkeratosis in mycosis fungoides.

The association of palmoplantar hyperkeratosis and mycosis fungoides (MF) has been described less frequently in the dermatologic literature. We present a patient with MF who developed hyperkeratosis of the palms and soles. Histologic examination of a specimen from the left palm showed microscopic changes of MF.

Humans↗
PubMed1985

Malignant pyoderma. Report of a case associated with a disorder of the immune system.

A 41-year-old man developed multiple suppurative ulcers and subcutaneous inflammatory nodules and abscesses on the face, the trunk and the extremities. Repeated bacterial and fungus cultures gave nonspecific and inconstant results. Light-microscopic studies showed diffuse inflammatory reaction in the dermis with abscess formation and tissue destruction. There was no evidence of blood vessel inflammatory changes. The course of the disease was characterized by marked chronicity and partial response to systemic steroid and antibiotic therapy. Treatment with clofazimine resulted in a marked improvement of the lesions. Laboratory test results suggest that a deficiency of cell-mediated immunity, associated with increased concentrations of immunoglobulins, may have been the pathogenic event in this case.

Adult↗