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Biomedical subjects

H Ashur

Publications and source records attributed to H Ashur.

At least 19 recordsLinked to original sources

Lipomatosis of the scalp and macrocephaly.

In summary, a case of macrocephaly and lipomatosis of the scalp and forehead has been presented. The phenotypic and clinical features found in our patient are in accordance with previous reports. The differential diagnosis with other hamartoneoplastic syndromes has been evaluated and discarded, concluding that the present report is in accordance with Bannayan-Zonana syndrome. However, as in other inherited traits, finding a genetic test to diagnose this entity remains a challenge.

Child, Preschool↗

[Passover hand injuries].

Almost every year just before Passover there is increased exposure to hand trauma in matzah bakeries. In the past 5 years we treated 11 cases of hand trauma incurred during matzah baking. The typical injuries were amputations at different levels, crush injuries and burns. We present a case seen last Passover and suggest preventive methods to eliminate these accidents in the future.

Accidents, Occupational↗

Extent of fiber regeneration after peripheral nerve repair: silicone splint vs. suture, gap repair vs. graft.

The degree of regeneration in surgically repaired sciatic nerves in rats was measured using a simple new electrophysiologic method: comparison of the size of nerve responses evoked by stimulation distal and proximal to the anastomosis. Five different repair procedures were evaluated. After simple end-to-end suture anastomosis, about 40% of the severed parent fibers regenerated past the suture line. The result was substantially improved when the anastomosis was covered with a newly designed thinwall silicone sheath which incorporated a narrow longitudinal slit. The presence of suture material at the point of anastomosis had no effect. Finally, regeneration across a 5-mm gap ensheathed in silicone (67%) was better than regeneration through a 5-mm autograft (45%).

Action Potentials↗

Healing and tensile strength of CO2 laser incisions and scalpel wounds in rabbits.

An experimental model was designed in order to compare the results of wound healing after skin incision by CO2 laser and scalpel. The skin of 36 rabbits was incised by a CO2 laser with a 15-W current output and by scalpel. The wounds were tested for tensile strength and histology after healing up to 4 weeks to determine if scalpel wounds differed from those made by the laser beam. Tensile strength tests showed that the wound incised by the laser beam was initially stronger up to 3 weeks; thereafter, the strength of both types of wounds was equal. Histologic preparations showed partial necrosis of the wound edges and a more extensive inflammation response in laser beam incisions which disappeared gradually from 2 weeks after incision. Because of initial stronger scar following laser beam incision as compared with scalpel incision, early mobilization of the operated limb is possible.

Animals↗

Low i.v. regional analgesia with bupivacaine for hand surgery.

A forearm tourniquet for i.v. regional analgesia of the hand, using doses of bupivacaine smaller than in the conventional (upper arm) method, produced successful analgesia in 98 of 102 patients. In 63 patients bupivacaine 50 mg or less was adequate, while in 33 the dosage was between 60 and 75 mg. No toxic effect was noted. This technique permits surgery of the hand, wrist and distal forearm.

Adolescent↗

Reimplantation of completely amputated rat limb.

A technique for the amputation and immediate reimplantation of rats legs was studied using a microsurgical technique. Complete survival of the reimplanted leg was achieved by basing the blood supply on anastomoses of arteries about 0.4 mm in external diameter. Anastomoses of vessels in that range by interrupted sutures of 10/0 and 11/0 black monofilament nylon proved to be compatible with leg survival. The ultimate survival of the reimplanted limbs depended upon microsurgical technique, preoperative and operative heparinization and external protection during the recovery phase. Animals are alive and using the replanted limb, several months postoperatively.

Amputation, Surgical↗

Calcified ballbladder (porcelain gallbladder).

Calcification of the gallbladder wall, otherwise known as porcelain gallbladder, is a relatively rare disease and is frequently asymptomatic. Symptoms suggestive of biliary disease are often absent in patients with this manifestation. Since the condition is uncommon, it is important to recognize the clinical as well as the roentgenographic characteristics of the disease because of the high frequency (22%) of adenocarcinoma in the porcelain gallbladder. To our knowledge, no pathognomic sign of symptoms of the disease have been reported so far. Of five cases of porcelain gallbladder reported, carcinoma of the gallbladder was discovered in one patient. This disease seems to appear mostly in the sixth decade of life and is more prevalent in women. Diagnosis is made in most cases by a simple flat plate of the abdomen, and workup should include other roentgenographic examinations to exclude calcification of other viscera or the thoracic wall. Surgery should not be delayed even if the patient is asymptomatic since the occurence of carcinoma in porcelain gallbladder is remarkably high.

Adult↗

An unusual case of median cleft lip with orbital hypotelorism--a missing link in the classification.

De Myer (1963) classified median-facial anomalies into two groups: 1. Median cleft lip with orbital hypotelorism 2. Median cleft lip with orbital hypertelorism. The first group is characterised by median-cleft lip, absence of premaxilla, nasal skeleton, and crista galli. In addition, there is a holoprosencephaly which may involve the whole forebrain or a smaller part of the brain. In this group, the children die within the first year or during childhood and always suffer from mental retardation. In this report, we present a 12-year-old child with an unusual form of median cleft lip with hypotelorism without brain deformity.

Child↗

Lymphedema of the hand following a fracture of the distal radius.

A case of chronic lymphedema of the hand and forearm following a fracture of the distal radius is reported. None of the classic causes of secondary lymphedema appeared to be the cause. A strong psychogenic component appeared to be the underlying mechanism. This rare phenomenon was thought to be self-induced and not genetic in nature.

Adult↗