Biomedical subjects

H Ata

Publications and source records attributed to H Ata.

4 recordsLinked to original sources

PubMed1980

[Penicillinase activity of staphylococci and their sensitivity to penicillin G and oxacillin (author's transl)].

The penicillinase activities of 169 strains of staphylococci isolated from outpatients were detected by a simple technique that gives the result in 10 minutes on benzylpenicillin and bromocresol purple absorbed Whatman No 1 filter papers. Seventy three out of 100 S. aureus strain and 4 out of 69 S. albus were found to have the enzyme. The ratio of penicillin G resistance among S. aureus and S. albus were found to be 89% and 41% respectively. Six strains (6%) of S. aureus and 5 (7%) S. albus were resistant to both antibiotics. When the findings were compared with those previously reported in Turkey, it was seen that the proportion of the penicillinase + strains and the incidence of resistance in staphylococci to both kinds of penicillins was increased.

Humans↗

PubMed1980

[Brucellosis outbreak in Oltan village of Ankara (author's transl)].

There has been significant increase in the number of brucellosis cases admitted to our clinic within first 6 months of 1979. Since most of the cases were from Ayaş, Polatli and Oltan villages we visited Oltan and examined 97 persons 23 of whom had complaints of fever, arthralgia and sweating. In addition to previous 5 cases, 5 more patients were found to have antibody titers of 160-640. In the control group none of the randomly chosen outpatients had titers higher than 40. Three milk samples taken from 12 sheep also had antibodies against brucella. Six B. melitensis strains isolated from these and the other patients were sensitive to terramycin, rifampicin and streptomycin; but resistant to sulfonamide, chloramphenicol and clindamycin. Four of them were sensitive to bactrim and ampicillin. In this paper, the findings of 17 cases of brucellosis other than from those of Oltan have also been presented.

Animals↗

PubMed1980

[Interactions between antibiotics (author's transl)].

Combined antibiotic therapy has been used frequently to obtain broader antibacterial spectrum because of increased antibiotic resistance in microorganisms. However, antibiotics should not be combined for purposes of synergy except in certain serious infections or in infections which cannot be treated with a single drug. Other than antagonism, potential deleterious effects of combined therapy such as broader suppression of normal bacterial flora, greater risk of secondary infections and increased adverse reactions may occur during the treatment. The results of in vivo and in vitro studies in the use of combinations may be different and sometimes good clinical results can be observed with a combined therapy which is antagonistic in vitro. But, this antagonistic interaction will no be sufficient. Therefore, at the beginning of the antibiotic therapy pathogenicity of the infectious agent, defence mechanisms of the patient and the type of interaction between antibiotics must be carefully considered.

Anti-Bacterial Agents↗

PubMed1977

[Fungal infections following renal transplantation].

Following the immunosuppressive treatment, applied after renal transplantations, infectious diseases are seen more frequently. Inspite of more frequency of bacterial infections, they can usually be controlled because of their easier diagnosis and treatment. However the mycotic diseases are usually fatal because of their easier diagnosis and treatment. However the mycotic diseases are usually fatal because of the difficulty in their diagnosis and treatment. The immunosuppressive treatment agents are cytotoxic medicines, codticosteroids, antilymphocytic sera (or antithymocytic sera) and radiation. The mycotic infections, more often encountered are candidiasis, aspergillosis, nocardiosis, cryptococcosis and phycomycosis. There are certain medicines used today in the treatment of deep mycotic infections. These are amphotericine B, 5 fluorocytosine and imidazol derivatives.

Amphotericin B↗