Reintroducing: Hilda Bessie Allen (nee Forrester) "Frostie". Interview by Ann Shaw.
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Biomedical subjects
Publications and source records attributed to H B Allen.
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Three patients with acquired digital fibrokeratoma are presented herein. This tumor may be confused clinically with other lesions including supernumerary digits, fibromas, neuromas, and neurofibromas. As a result, the histologic picture is most helpful in making a correct diagnosis. Since this lesion has been noted to occur in areas other than the digits, a more appropriate designation may be "acquired fibrokeratoma".
Concomitant allergic reactions to manganese and cadmium sulfide developed in a patient in tattooed areas. Although the reaction to cadmium was elicited by sunlight, attempts to reproduce it with artificial long-wave ultraviolet light were unsuccessful.
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Examination of specimens from lesions of hyperpigmented tinea versicolor and from unaffected skin disclosed that the lesions showed increased stratum corneum turnover (8.2 +/- 0.6 vs 14.8 +/- 0.4 days, respectively), slight to moderate routine histological changes, such as acanthosis and perivascular inflammation, and dramatic electron microscopical changes (larger, singly distributed melanosomes vs small, packaged melanosomes, respectively). Brown hyperpigmentation in tinea versicolor appears to arise from an increase in melanosome size and a change in their epidermal distribution pattern.