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Biomedical subjects

H B Andersson

Publications and source records attributed to H B Andersson.

3 recordsLinked to original sources

Nondigestibility characteristics of inulin and oligofructose in humans.

The ileostomy model is considered to be a reliable model to reflect small bowel absorption. Studies in ileostomy subjects have shown that inulin and oligofructose pass through the small bowel without degradation and without influencing the absorption of nitrogen, fat, starch, calcium, magnesium or zinc. Inulin and oligofructose do not have any considerable effect on cholesterol absorption or bile acid excretion.

Cholesterol, Dietary↗

Heat-induced changes in casein-derived phosphopeptides.

Phosphopeptides derived from casein may function as carriers for calcium and trace elements. In regard to such specific nutritive effects, the heat-induced changes in tryptic phosphopeptides liberated from bovine sodium caseinate as a model system were investigated. Both microwave and oven heating resulted in a marked loss of peptide-bound phosphorous (dephosphorylation) and a decrease of casein-phosphopeptides in the soluble part of the tryptic hydrolysate. It is concluded that hydrolysis of phosphoseryl to seryl residues was the prevailing degradation step to soluble proteolytic products, whereas lysinoalanyl-casein is claimed to be present almost exclusively in the pH 4.6-insoluble part of the tryptic digest.

Animals↗

Short-term effect of two cholesterol-lowering diets on sterol excretion in ileostomy patients.

The effect of two cholesterol-lowering diets (PUFA, LO) on the excretion of bile acids and neutral sterols, measured by GLC, was studied in six healthy ileostomates. The reference diet contained 100 g of fat and 13 g of dietary fiber. PUFA was increased in polyunsaturated fatty acids but fat level remained the same. LO was reduced in total fat with a concomitant increase in dietary fiber. Bile acid, net cholesterol, and net sterol excretion increased by 22%, 28%, and 24% (p less than 0.01), respectively, on PUFA. On LO, net cholesterol and net sterol excretion increased by 27% and 18% (p less than 0.01), respectively. Results support the concept of changes in sterol excretion as a mechanism for changes in blood-lipid levels induced by cholesterol-lowering diets.

Adult↗