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Biomedical subjects

H B Desai

Publications and source records attributed to H B Desai.

5 recordsLinked to original sources

Use and abuse of drugs in the elderly.

1. Study of 100 patients admitted to the Geriatric Assessment Unit, to evaluate the appropriateness of drug therapy in the elderly. 2. Average patient took 5.15 drugs at admission and 3.67 drugs at discharge. 3. Inaccurate dosages found in 14%, drug-drug interaction in 31%, drug contraindications were evident in 23% and at least one unnecessary drug was prescribed in 39% patients at admission. 4. At discharge, 8% cases had potential drug-drug interaction and 2% received unnecessary drugs.

Aged

Amyotrophic lateral sclerosis in a patient with fragile X syndrome.

Fragile X syndrome is a common cause of mental retardation. We report the clinical and pathologic features of a patient with fragile X syndrome who developed amyotrophic lateral sclerosis (ALS) at a relatively young age. Although the occurrence of these 2 diseases could be a mere coincidence, the development of ALS in this patient might be related to the chromosomal aberration of fragile X syndrome.

Adult

Recurrent spinal cord ischemia due to abdominal aortic aneurysm--a case report.

Ischemic spinal cord lesions with abdominal aortic aneurysm are rare and are usually characterized by a single catastrophic event. The authors report a seventy-five-year-old woman who, over a period of three years, had three attacks of acute neurologic deficit. The clinical features were those of bladder incontinence, a mixture of upper and lower motor neuron lower limb motor deficit, and patchy sensory loss with a sensory level at T10-12. Investigations revealed a large abdominal aortic aneurysm that had enlarged with time. This case, they believe, represents an example of recurrent ischemic myelopathy due to occlusion at the mouth of radicular arteries or recurrent embolic events in those vessels.

Aged