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H Bäzner

Publications and source records attributed to H Bäzner.

9 recordsLinked to original sources
PubMed2006

Patterns of reoccurrence of segmental dystonia after discontinuation of deep brain stimulation.

The pattern of reoccurrence of symptoms after discontinuation of deep brain stimulation (DBS) has not been systematically studied in dystonia. Eight patients (mean age (SD) 53.8 (14.4) years) with segmental dystonia at a mean follow-up of 11.3 (4.2) months were studied after implantation of bilateral DBS electrodes in the internal globus pallidus using a standard video protocol and clinical rating scales, immediately and at 2 and 4 h after switching off DBS. Dystonic signs returned sequentially, with a rapid worsening of phasic and a slower worsening of tonic dystonic components. In all patients, phasic dystonic features appeared within a few minutes, whereas the tonic elements of dystonia reoccurred with a more variable delay. Differential clinical effects when withdrawing DBS might reflect its influence on different pathophysiological mechanisms in dystonia.

Adult↗
PubMed2006

Chronic spinal cord stimulation in medically intractable orthostatic tremor.

BACKGROUND: Orthostatic tremor with its sense of unsteadiness when standing may have a devastating effect on affected persons. Currently, there are no other treatment options in those who do not respond or who do not tolerate medical treatment. OBJECTIVES: To report on a pilot study on spinal cord stimulation in medically intractable orthostatic tremor. METHODS: Chronic spinal cord stimulation (SCS) was performed in two patients with medically-intractable orthostatic tremor via quadripolar plate electrodes implanted at the lower thoracic spine. The electrodes were connected to implantable pulse generators. RESULTS: Subjective and objective improvement of unsteadiness was achieved within a frequency range of 50 to 150 Hz, and occurred in the presence of stimulation-induced paraesthesia. With optimized stimulation settings polygraphic electromyelogram (EMG) recordings continued to show the typical 14-16 Hz EMG activity. The beneficial effect of SCS was maintained at long-term follow-up. CONCLUSIONS: The results of this pilot study indicate that SCS may be an option in patients with otherwise intractable orthostatic tremor.

Aged↗
PubMed2006

[The consequences of stroke for the artist Lovis Corinth].

The artist Lovis Corinth suffered a right-hemispheric stroke at the age of 53 years but only died 14 years later. The huge amount of work he produced after this life threatening disease allows detailed analysis of his post-stroke artwork in comparison to pre-stroke. When performing this analysis as a neurologist, an enormous diversity of subtle stroke sequelae can be discovered that are mostly explained by left-sided hemi-neglect. These findings clearly go far beyond pure psychological processes. Moreover, Corinth is a motivating example for disabled patients because he was able to produce great artwork after his stroke. He was struggling against a motor disability admittedly not severely affecting his artistic production, but also against severe neuropsychological deficits that did have clear consequences. Lovis Corinth left us the credo "True art means to use unreality". Taken together with the often cited phrase "Drawing means to leave out (details)", a clear-cut interpretation for neurologists can be derived from the understanding of right-hemisphere lesions and subsequent left-sided neglect.

Persons with Disabilities↗
PubMed2006

[Asymptomatic carotid stenoses. Course and discussion of their treatment].

Asymptomatic carotid stenoses are common. They are associated with the risk factors for arteriosclerosis and are a specific risk factor for coronary artery disease, with an annual morbidity/mortality (MM) rate of 8-10%. Detection of a carotid stenosis should therefore be followed by a complete risk factor analysis and modification, if appropriate; a thorough cardiological diagnostic investigation is particularly important. Individual risk indicators for stroke (annual MM 1-2%) are a rapid progression of the degree of stenosis, certain morphological patterns and the presence of extra- and intracranial multi-vessel disease. Trials available so far on the treatment of asymptomatic carotid stenosis have not revealed any significant parameters that would justify individual decisions on whether or not surgery is appropriate. There is therefore a danger that many patients will be exposed to a severe risk of stroke, which cannot be justified unless the centres where such interventions are performed have proven MM complication rates of <3%, the life expectancy of the patients treated is not restricted as the result of other illnesses and the patients explicitly request surgery after a thorough explanation of the risks. Conservative treatment strategies provide the best protection for the majority of patients.

Carotid Stenosis↗
PubMed2006

Stroke in painters.

Explore the source record for details and available documents.

Adaptation, Physiological↗
PubMed2004

Georg Friedrich Händel's strokes.

Georg Friedrich Händel was a musical giant and probably the first composer to be the manager and promoter of his own works. The story of his life and illnesses is full of myths, invented and embellished by various biographies. Existing pathographies written by authors from various specialities suggested he suffered from psychiatric diseases like cyclothymia or mania and rheumatologic disorders like arthritis, while others tended to interpret his recurrent palsies as typical sequelae of ischemic strokes. During the last years of life, Händel was struck with blindness, which in his era was interpreted as being due to cataracts. This led to three 'coucher' operations, all of them without lasting effect. Although a definite diagnosis cannot be inferred from the original sources, the most plausible explanation for Händel's palsies and visual impairment may be cerebrovascular disease. The possible differential diagnosis will be discussed in this paper.

Blindness↗
PubMed2000

Assessment of gait in subcortical vascular encephalopathy by computerized analysis: a cross-sectional and longitudinal study.

In subcortical vascular encephalopathy (SVE) gait disturbance is a common and early clinical sign which might be used to monitor disease progression. In the absence of reliable scales and with regard to the equivocal results of highly complex gait imaging devices we assessed the natural course of SVE in a prospective study, using a new straight forward technique to quantify and compare sequential gait studies. We report the results of 300 computerized gait analyses in 119 patients with SVE and 63 age-matched controls. Thirty-nine SVE patients were re-evaluated to monitor the natural course of the disease and to study the correlation of gait disturbances with MRI changes and neuropsychological findings. The system consists of a set of shoes containing 16 load sensors and a measuring-unit reading each sensor at 20-ms intervals. By off-line analysis we graded each recording on a Gait Disorder Score (GDS) with six variables indicating gait steadiness: step frequency, length of gait lines (which represent the movement of the centre of gravity during heel to toe movement), length of single support lines, variability of single and of double support lines, and double support time. In cross-sectional analysis, patients with SVE showed cadence (steps/min) to be reduced at 87.3 +/- 19.5 (96.4 +/- 7.8 in controls, P < 0.05). Length of gait lines was significantly less: 0.70 +/- 0.13 vs. 0.80 +/- 0.05 in controls, with length of single support gait lines reduced at 0.42 +/- 0.14 in SVE (0.58 +/- 0.06 in controls, P < 0.05). Variability of both single support lines (5.69 +/- 1.90%; 4.24 +/- 1.07% in controls, P < 0.05) and double support lines was elevated (3.59 +/- 1.62% vs. 2.54 +/- 0.59%), while duration of double support phases was increased (0.19 +/- 0.10 s vs. 0.13 +/- 0.02 s in controls, P < 0.05). The progressive character of the disease was demonstrated by increasing GDS values in 39 SVE patients with a frontal gait disorder who were re-investigated after a mean interval of 26 months (5.4 +/- 4.5 vs. 8.4 +/- 5.5, P < 0.05). This study shows the value of a new and practicable gait analysis system for the evaluation of gait disorders and it quantifies the deterioration of gait in SVE patients.

Aged↗
PubMed1995

Modification of low-frequency spontaneous oscillations in blood flow velocity in large- and small-artery disease.

During a 30-minute period, the blood flow velocity of both middle cerebral arteries (MCAs) was measured bilaterally in 27 patients with obstructive carotid disease (n = 18, large-artery disease) or subcortical vascular encephalopathy (n = 9, small-artery disease) and in control subjects of similar age and sex distribution (n = 14). To identify low-frequency spontaneous oscillations (LFSOs), MCA envelope curves were Fourier transformed with filter application to select low-frequency spectra (0.01-0.05, 0.05-0.15, 0.15-0.50 Hz). To measure the extent of LFSO amplitudes, a coefficient of variation (CoV) was calculated. In addition, a coefficient of correlation (CoC) was calculated to assess LFSO bilateral synchronicity. Normal ranges for CoV (mean = 5.38 +/- 1.82%) and CoC (mean = 0.91 +/- 0.06) were established in control subjects. In patients with large-artery disease, a significant CoV reduction was observed ipsilateral to the carotid lesion (CoV mean = 3.91 +/- 1.10%; p < 0.05, Wilcoxon's test) with a contralateral compensatory increase (CoV mean = 5.68 +/- 1.79%). In addition, a significant desynchronization of LFSOs was found in patients with large-artery disease (CoC = 0.39 +/- 0.35, p < 0.05). This was less obvious in patients with small-artery disease, who demonstrated a marked bilateral reduction of LFSO activity (CoV mean = 3.60 +/- 0.71%, p < 0.05) and CoC values.(ABSTRACT TRUNCATED AT 250 WORDS)

Aged↗