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H Børner

Publications and source records attributed to H Børner.

4 recordsLinked to original sources

Striatal dysfunction in attention deficit and hyperkinetic disorder.

We have previously reported that periventricular structures are hypoperfused in attention deficit and hyperactivity disorder (ADHD). This study has expanded the number of patients, who were divided into two groups: six patients with pure ADHD, and 13 patients with ADHD in combination with other neurologic symptoms. By using xenon 133 inhalation and emission tomography, the regional cerebral blood flow distribution was determined and compared with a control group. Striatal regions were found to be hypoperfused and, by inference, hypofunctional in both groups. This hypoperfusion was statistically significant in the right striatum in ADHD, and in both striatal regions in ADHD with other neuropsychologic and neurologic symptoms. The primary sensory and sensorimotor cortical regions were highly perfused. Methylphenidate increased flow to striatal and posterior periventricular regions, and tended to decrease flow to primary sensory regions. Low striatal activity, partially reversible with methylphenidate, appears to be a cardinal feature in ADHD.

Attention Deficit Disorder with Hyperactivity↗

Anorexia nervosa/bulimia in diabetes mellitus. A review and a presentation of five cases.

Review of recent literature with emphasis on growth, development and epidemiology of eating disorders and diabetes reveals many common features of the conditions. Thus we hypothesize more concurrence than would occur by chance alone. At present epidemiological evidence is inconclusive, but prevalence of eating disorder seems increased in insulin dependent diabetes mellitus (IDDM). Over a period of 25 years five cases (all female) of diabetes were found in a consecutive series of 242 patients with eating disorders treated at the Child Psychiatric and Psychiatric Clinics at Rigshospitalet, Copenhagen, Denmark. This is a six-fold increase in prevalence of IDDM. IDDM preceded eating disorder (anorexia nervosa (AN)/bulimia(B)) in four of the five cases, and contributed significantly to the psychopathology found: the more, the earlier the age at onset of IDDM. Treatment proved difficult and the outcome seems serious. At latest contact four cases had manifest eating disorders and three of these had unstable and complicated IDDM as well. The patients' adaptation to IDDM seems crucial for the outcome.

Adaptation, Psychological↗