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Biomedical subjects

H Beckers

Publications and source records attributed to H Beckers.

At least 19 recordsLinked to original sources

Inter-observer variation in the assessment of skin ulceration.

Six observers (three physicians and three nurses) assessed 27 wounds of different types in 20 elderly patients, using five different classification systems. Using classification by colours, inter-observer agreement was moderate when six colours were used (70% agreement, group kappa 53%), and good if this was reduced to three (80% agreement, group kappa 64%). Results were only moderate using the Shea scoring system (68% agreement, group kappa 42%). Assessment for signs of infection was fair to moderate (75-85% agreement, group kappa 29-55%), but there was high inter-observer agreement for size and area (analysis of variance, p > or = 0.88).

Humans↗

Sympathetic innervation of the rat's eye and peripheral ganglia: an electron microscopic autoradiographic tracing study.

The sympathetic innervation of the rat anterior eye segment and related peripheral ganglia was studied using light and electron microscopic autoradiography after anterograde tracing with 3H-leucine from the superior cervical ganglion. In the trigeminal and pterygopalatine ganglia, unmyelinated nerve fibers were labeled. Some fibers contained accumulations of small vesicles. Close apposition of these labeled sympathetic fibers with other unmyelinated fibers was common, and was also observed at sites where accumulations of vesicles were found. In the iris, ciliary body and trabeculum, numerous fibers and vesicle-containing varicosities were labeled, which all had a similar morphology. No labeling was found in the cornea. Sympathetic fibers traversing the trigeminal and pterygopalatine ganglion closely appose other unmyelinated fibers and contain clusters of vesicles without forming classical synaptic contacts. However, non-synaptic information transfer needs further investigation. The anterior eye segment, except for the cornea, is densely innervated by sympathetic nerve terminals.

Animals↗

Collaborative study on the use of motility enrichment on modified semisolid Rappaport-Vassiliadis medium for the detection of Salmonella from foods.

A collaborative study was performed in 15 laboratories to evaluate the use of motility enrichment on modified semisolid Rappaport-Vassiliadis (MSRV) medium for rapid Salmonella detection in a variety of food products. The results of this procedure were compared with those obtained by the cultural procedure using Rappaport-Vassiliadis (RV) broth as selective enrichment and modified brilliant green agar for selective plating. The tests were performed with Salmonella reference samples (SRS) as well as with naturally contaminated food products. When SRS were used without added food the productivity of both MSRV and RV was 96%. When SRS were combined with reference samples containing competitive bacteria the productivity was 98% for MSRV and 95% for RV. In the tests with food samples the productivity of MSRV was 92% with SRS added to food and 96% with naturally contaminated samples, while the productivity of RV was 88% and 90%, respectively. Statistical analysis showed that there was no significant difference between the procedures.

Culture Media↗

[Primary management of 2 unusual facial injuries].

In the first patient a spinning saw-blade cut through the soft tissues and bony structures of the face in a paramedian, vertical section; in another patient a dum-dum bullet fired in suicidal intention from submentally destroyed the frontal half of the mandible and maxilla, the nose and the medial part of both orbits. The facial soft tissues, however, suffered only minor injuries. In the first patient the immediate treatment included inspection of the frontal sinus, preserving all loose bone fragments, and immediate reconstruction of the medial orbital frame employing bonewires, identification of the lacrimal ducts, reapproximation and stabilisation of these ducts with very flexible silicone threads, soft-tissue closure employing a running z-plasty, interdigitating the z-shaped wound edges caused by the saw. In the second patient stability of the remaining mandibular portions was achieved by mandibular reconstruction plates to which all remaining mandibular bone fragments were attached with bone screws or wires. The stabilized mandible allowed suspension of the tongue.

Adult↗

Evaluation of the ELISA as tool in diagnosing Clostridium perfringens enterotoxins.

Detecting Clostridium perfringens enterotoxin (CPE) using the enzyme linked linked immunosorbent assay (ELISA) was evaluated as a tool for diagnosing enterotoxicosis caused by C. perfringens. This method was assessed using a number of different food poisoning outbreaks with possible C. perfringens associations. CPE can easily be detected in faeces of patients involved in food-borne disease caused by C. perfringens. In stools of patients with diarrhoea 0.01-10 micrograms/g of CPE is detectable, however not all samples examined are found to contain CPE. CPE in faeces maintains its immunological stability over a long period (greater than 20 days at room temperature) enabling samples to be stored for some time before assay. The ELISA technique is also useful for the detection of CPE in culture fluids of C. perfringens strains isolated from faeces and from any remaining food considered to have caused the food poisoning outbreak. Detection of CPE in stools combined with testing for CPE production in C. perfringens strains isolated both from faeces and from the suspect food seems to give good evidence linking a food-borne disease outbreak with C. perfringens.

Clostridium Infections↗

The use of ultrasound in the diagnosis of pelvic pathology.

At the Universitäts-Frauenklinik Köln (Cologne) 515 patients with gynecological symptoms underwent 597 clinical and ultrasound examinations; 224 patients had a subsequent laparotomy which offered means of checking the clinical and ultrasound findings. There was full agreement between ultrasound and clinical examination in 80%, partial agreement in 9%, and no agreement in 11%. Ultrasound provided information not gained by clinical means in 12%. In those patients subjected to operation clinical examination provided correct and complete diagnoses in 70% of patients, partially correct diagnoses in 19%, and wrong diagnoses in 11%. Ultrasound, however, provided correct diagnoses in 78%, partially correct diagnoses in 14%, and wrong diagnoses in only 8%. The results of ultrasound and clinical findings tallied in 51%, in 38% the ultrasonogram provided more precise information than palpation, and in 11% the clinical findings were more revealing than ultrasound examination. Additional valuable information was provided by 13% of ultrasonograms. Ultrasonography was not a precise predictor of malignancy.

Abdominal Neoplasms↗

[Compression plate osteosynthesis in infected mandibular fractures].

Self-compromising osteosynthesis plates proved satisfactory for 19 patients with infected fractures of the mandible. After immediate stabilization of the fracture with osteosynthesis plates, the abscess was incised and drained, and antibiotic therapy was instituted. All the fractures consolidated without significant complications. Radiologic assessment revealed delayed bony healing. Our findings agree with those in the field of general traumatology for treating infected fractures.

Anti-Bacterial Agents↗