Biomedical subjects
Publications and source records attributed to H Berendtsen.
The most common method for female sterilization in Denmark is laparoscopic tubal application of Filshie clips. We describe a case of a 35 year old women admitted with a right inguinal abscess. A Filshie clips that had been inserted five years earlier was found by surgical exploration of the abscess. Possible pathogenetic and etiological factors are discussed.
Three hundred and sixty-five women were operated for ectopic pregnancy at the Department of Gynecology and Obstetrics, Odense University Hospital in a 13-year period. In all cases, the diagnosis was verified by histological examination. In 245 cases there was curettage material available for histological examination. The slides were reviewed by one pathologist. The most common types of endometrium associated with ectopy were decidual reaction (42%), secretory endometrium (22%) followed by proliferative endometrium (12%). The endometrial changes classically considered as suggestive of ectopic pregnancy were found only in 53% of the cases. The histological examination of all this curettage material reveals a wide variety of endometrial histologies associated with ectopy: any type of endometrium without trophoblasts may be associated with ectopic pregnancy.
Abnormal serum zinc and copper concentrations in pregnant women have been associated with a number of maternal and foetal complications during pregnancy and delivery. However, the results of previous studies are contradictory and few large scale studies have been reported. In this study we measured serum zinc and copper concentrations in maternal and umbilical cord blood from 500 Danish mothers at delivery, looking for an association between serum zinc and copper levels and various maternal and foetal complications. Preterm infants (n = 30) had significantly lower serum copper concentrations than reference infants (n = 346) (p = 0.01), whereas there was no difference in serum zinc concentrations. Mothers of preterm infants (n = 34) did not differ in serum zinc or copper concentrations from reference mothers (n = 220). Small for date infants (n = 37) and mothers of small for date infants (n = 47) had higher serum copper levels than reference infants and mothers (p = 0.02 and p = 0.04, respectively), whereas there was no difference in serum zinc concentrations. Serum zinc and copper concentrations in malformed infants (n = 14) and their mothers (n = 17) did not differ from concentrations in reference infants and mothers. Serum zinc and copper concentrations in mothers with various other complications during pregnancy and delivery did not differ from values in mothers with normal pregnancies and deliveries.
The present knowledge of the role of selenium in human fetal and neonatal development is sparse. In this study we measured serum selenium concentrations in maternal and umbilical cord blood from 500 Danish mothers at delivery, looking for a relationship between various maternal and fetal complications and selenium values. In mothers with uncomplicated pregnancies and deliveries serum selenium concentrations were 0.84 +/- 0.19 mumol/l (mean +/- SD), whereas in cord blood from full-term babies born adequate for gestational age and with no malformations serum selenium concentrations were 0.60 +/- 0.11 mumol/l (mean +/- SD). Mothers who received mineral tablets (other than iron preparations) during pregnancy had significantly higher serum selenium values than unsupplemented mothers (0.92 versus 0.70 mumol/l) (p less than 0.001). Infants of mineral-supplemented mothers also had significantly higher serum selenium values than infants of unsupplemented mothers (0.62 versus 0.58 mumol/l) (p less than 0.001). Preterm infants had significantly lower serum selenium concentrations than full term infants (0.54 versus 0.60 mumol/l) (p = 0.01), whereas infants small for gestational age did not differ in serum selenium concentrations from infants adequate for gestational age. Serum selenium concentrations in malformed infants tended to be lower than in normal infants (0.55 versus 0.60 mumol/l) (p = 0.09), but the difference was not statistically significant, probably due to the small number. Serum selenium concentrations in mothers with various complications during pregnancy and delivery did not differ from values in mothers with uncomplicated pregnancies and deliveries.
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