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Biomedical subjects

H Bergstedt

Publications and source records attributed to H Bergstedt.

16 recordsLinked to original sources

Further studies on a male monozygotic triplet with schizophrenia: cytogenetical and neurobiological assessments in the patients and their parents.

We previously described a Swedish set of male schizophrenic monozygotic triplets. In this study the patients as well as their parents were further characterized. By high-resolution chromosomal analysis an extra band at chromosome 15p was found in all the triplets and the father. Microdissection, degenerate oligonucleotide-primed PCR (DOP-PCR) amplification and reverse painting indicates that the extra band probably contains only repetitive DNA sequences with no known effect on the phenotype. Magnetic resonance imaging (MRI) showed similar borderline ventricular enlargement and widened subarachnoid spaces over frontoparietal and basal regions as well as around the pituitary gland (empty sella) in all the triplets. The father also had widened subarachnoid spaces over the frontal and basal regions. The mother had an empty sella indicating widened subarachnoid spaces. All the boys also had a right-sided conductive hearing defect, probably due to malformation and fixation of the ossicular chain. The parents did not present any otological abnormalities. Neuropsychological assessment demonstrated similar marked reductions of attentional, mnestic, and executive functions in all the triplets, but the mother showed a normal pattern. Possible joint etiological mechanisms for the psychological and somatic abnormalities recorded in the triplets are discussed.

Adult↗

Synovial chondromatosis of the temporomandibular joint. Report of a case.

A case of synovial chondromatosis of the temporomandibular joint is reported in which initial clinical and radiographic data indicated disk derangement. Magnetic resonance imaging revealed distention and thickening of the lateral capsule but could not delineate the numerous loose bodies found at arthrotomy. The literature is reviewed, and diagnosis and surgical therapy are discussed.

Arthroscopy↗

A special cut-off gamma camera for high-resolution SPECT of the head.

A modern system for single photon emission computerized tomography has been modified in order to optimize examinations of the head. By cutting off part of the detector housing and collimators at one edge, it is possible to rotate the camera close to the skull while still covering the entire brain and the skull base. The minimum radius of revolution used in 32 patients was thereby reduced from about 20 cm to 12.7 +/- 0.8 cm. This, combined with an adjustment of the 64 X 64 matrix to a 26- by 26-cm field of view, resulted in an improvement of the spatial resolution from about 19 mm to 12.6 +/- 0.3 mm with a low-energy, all-purpose collimator, and to 10.4 +/- 0.3 mm (FWHM) with a low-energy, high-resolution collimator. The improved spatial resolution offers several clinical advantages in studies of the brain, the cerebrospinal fluid space, and the skull base.

Adult↗

Split-rib graft for reconstruction of the mandible.

Defects in the mandible after tumor surgery were reconstructed with split-rib grafts in 23 patients. Twenty of the patients were preoperatively irradiated with fractioned radiotherapy, ranging from 40 to 85 gray. Partial sequestration appeared in five patients. The ingrowth of the transplant was examined with technetium scintigraphy. Satisfactory cosmetic and functional results were achieved in the great majority of the patients. Split-rib grafting is recommended for reconstruction of the mandible as a safe procedure with little increased operation time and morbidity for the patient and good functional and cosmetic results.

Aged↗

[Head trauma with resultant irreversible deafness on one side and reversible hearing impairment on the other side. A case report].

Following a severe head trauma, a 27-year-old man immediately suffered from bilateral hearing loss and impaired balance. On examination there was a complete loss of hearing on the right side. On the left side a subtotal hearing loss of sensorineural origin occurred and became total after a few days. The vestibular function was absent on both sides. Following treatment with prednisolone, hearing recovered in the left ear and reached an average tone threshold of 55 dB. The vestibular function remained lost from the onset of the trauma. At follow up two years later the subtotal hearing loss in the left ear was unchanged as was also the vestibular impairment.

Acoustic Impedance Tests↗

Jaw cysts with special regard to keratocyst recurrence. A long-term follow-up.

From an original material of 50 patients with 55 jaw cysts, 39 patients were followed up 32--129 months after surgery (mean: 92 months). In 21 of 55 cysts the primary lesion was histologically classified as a keratocyst. All keratocysts had a follow-up period of at least 6 years (72 months). The keratocyst recurrence rate was 50%. Seven of eight recurrences in the total material were keratocysts. There was no difference between males and females concerning the incidence of keratocysts or age at diagnosis.

Adolescent↗

Congenital malformation of the inner ear and recurrent meningitis. A case report.

Congenital deformities of the inner ear can be associated with meningitis and varying degrees of hearing loss or deafness. Recurrent periods of meningitis, sometimes lethal, are due to communication between the middle ear cavity and the subarachnoid space. Different types of congenital dysplasia have been classified earlier and we report a 3-year-old girl with unilateral deafness, episodes of meningitis and a malformation of the inner ear and the footplate of the stapes.

Child, Preschool↗

Discrimination of purulent from nonpurulent maxillary sinusitis. Clinical and radiographic diagnosis.

For the rational treatment of sinusitis, it is essential to distinguish sinusitis of bacterial origin from that of other etiologies. In maxillary sinusitis, antral purulence indicates a significant amount of pathogenic bacteria, whereas the presence of bacteria seems to be of less or no relevance in nonpurulent sinusitis. Hence, from a therapeutic point of view one important diagnostic goal is the differentiation of purulent from nonpurulent sinusitis. In this respect clinical examination is fairly reliable. Sinus radiography cannot distinguish purulent from nonpurulent sinusitis and offers few advantages when deciding on antibiotic therapy. Antral aspiration offers the most comprehensive information on which to base a reliable diagnosis.

Biopsy, Needle↗