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H Berthold

Publications and source records attributed to H Berthold.

122 records · Page 7Linked to original sources
PubMedDate not supplied

Nuclear particles of non-A, non-B type in healthy volunteers and patients with hepatitis B.

In an electron microscopic study, nuclear aggregates of virus-like spherical and tubular particles measuring 20 to 29 nm in diameter were found in 5 of 7 clinically healthy volunteers with normal liver histology, 6 of 10 patients with hepatitis B and 17 of 18 patients with hepatitis non-A, non-B. The incidence of hepatocytes containing nuclear particles was approximately 0.5 to 2% in all three groups. We conclude that these nuclear particles are not specific ultrastructural markers of hepatitis non-A, non-B in man as originally claimed for experimental hepatitis non-A, non-B in chimpanzees.

Adolescent↗
PubMedDate not supplied

Epulis: a clinicopathological study of 120 patients with emphasis on recurrent lesions.

A total of 138 surgical excision specimens from 120 patients presenting clinically with epulis was classified by histopathological criteria into giant cell-, granulomatous- and fibromatous-type lesions. Clinical data suggest that local irritants are an important pathogenetic factor. Histopathological analysis revealed that epulides represented self-limiting, reactive gingival overgrowths of granulation tissue displaying common morphologic features in all three histologic types. The transition of a given histologic type of epulis into another, as observed in recurrent lesions, is consistent with the concept of a common histogenetic entity.

Adolescent↗
PubMedDate not supplied

[Efficacy of hepatitis B preventive vaccination].

Health care workers are at increased hepatitis B risk. In the course of a study with 5035 persons occupied at the Freiburg university hospital, efficacy of hepatitis B vaccination and duration of protection were investigated. Estimations of post-vaccination-anti Hbs showed that women, younger persons, persons with a body mass index < 25 and non-smokers had higher anti Hbs concentrations than men, elderly persons overweight persons and smokers. 2% of female and 1.5% of male vaccinees did not develop anti Hbs and 4.8% and 7.1%, respectively were low responders (anti Hbs < 100 < 10 IU/l). Estimations of vaccination efficacy revealed that even 10 years after basic immunisation at least 50% of all vaccinees should have anti Hbs concentrations > 100 IU/l. The results of the study show that vaccination of children in accordance with German and WHO recommendations will afford full protection (anti Hbs > 10 IU/l) in at least 99% of all cases.

Adult↗