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Biomedical subjects

H Bosseckert

Publications and source records attributed to H Bosseckert.

At least 19 recordsLinked to original sources
PubMed1991

[Comparison of 2 methemalbumin measurements and of free hemoglobin in view of their value in the differential diagnosis of edematous and hemorrhagic pancreatitis].

Methemalbumin was estimated by means of electrophoresis and the method of Walberg, respectively in 59 patients (25 pat. with edematous, 34 patients with hemorrhagic pancreatitis) partially over three days. In addition the estimation of free hemoglobin in ascites has been carried out. By both approaches of methemalbumin estimation there was no differentiation of the two pancreatitis forms possible. Though the method of Walberg was much more sensitive especially in the serum its specificity was correspondingly lower. The tendency to a correlation of the methemalbumin-concentration to the severity of the course of the disease could be observed. Such a correlation has been proved statistically for the free hemoglobin.

Acute Disease↗
PubMed1990

[Possible uses of laser in gastroenterology].

In the therapy of certain benign and malignant changes in the intestinal tract the laser stood the test. The absolute necessity of its use is limited, among others by existing alternative methods, so that a broadly disseminated equipment is not necessary. By the development of new types of laser and better handling systems (fibres with diffuse emission, fibres with lateral delivery of light and so on) its possibilities of application will enhance.

Endoscopes, Gastrointestinal↗
PubMed1990

[Papilla carcinoma and adenoma--diagnosis and therapy].

26 peripapillary adenomas and 64 papillary carcinomas are the background for a discussion of the adenoma-carcinoma-sequence in these tumours. An early diagnosis of the adenomas means in this context secondary prophylaxis of papillary carcinomas. Nowadays, the greatest difficulties consist in the differentiation of adenomyomatosis-like processes of the papilla and in the certainty that an adenoma has not changed to a carcinoma. In patients who cannot tolerate a greater surgical procedure the endoscopic papillotomy, possibly in combination with a prosthesis, is an appropriate measure.

Adenoma↗
PubMed1990

[Hyperplasiogenic polyps and stomach carcinoma risk--experiences following 1074 polypectomies and follow-up studies].

In 731 hyperplasiogenic polyps which have been removed by endoscopical polypectomy there were ten polyps with an early cancer and eight polyps with severe dysplasias (borderline lesions) as well as one polyp, in which an advanced carcinoma had developed. This is to date the greatest series of hyperplasiogenic polyps with malignant transformation. In addition, in nine patients with hyperplasiogenic polyps carcinomas could be discovered, i.e. a rate for malignancy of 3.8%. It seems that stomachs with multiple polyps are particularly endangered. The recurrence rate on follow-up examinations covering a period of up to eight years was 36.1%.

Cell Transformation, Neoplastic↗
PubMed1990

[Combination of glandular and foveolar hyperplasia of the gastric mucosa--a rare mixed type].

In a 28 year-old man with epigastric pain endoscopy detected giant gastric folds and multiple superficial erosions. Histologically a mixed form of glandular and foveolar hyper plasia of the gastric mucosa was suggested (Ming's type III). Basal and pentagastrin stimulated secretion volume and acid output were moderately elevated, hypersecretion of protein was not found. Serum levels of calcium and gastrin were normal, also after secretin stimulation. The mucosa of the corpus was extensively infested with Campylobacter pylori. Therapy with cimetidine, antacids, pirenzepine and metronidazol resulted in relief of symptoms but not of histological findings. Bismuth (JatroxR) was successful in eradicating Campylobacter pylori and decreasing inflammation of the mucosa. Cause and prognosis of this mixed hyperplasia are not known.

Adult↗
PubMed1990

[Pathophysiologic aspects of diarrhea].

Introductory the anatomical particularities of the small and large bowel in their connection to absorption and secretion are represented. According to that the paper of pathophysiological processes by the hand of typical examples of the different kinds of diarrhoea (osmotic-, secretoric-, motility induced diarrhoea, diarrhoea by morphological changes of the small- and/or large bowel, diarrhoea by disturbances of the active ionic transport) has been taken place.

Diarrhea↗
PubMed1988

[Primary clinical, endoscopic and histologic findings in solitary rectal ulcer].

This study presents clinical, endoscopical and histological primary findings of solitary ulcer of the rectum obtained in 24 patients. Solitary ulcer of the rectum is preferably a disease of young women. The main symptom is recurrent rectal bleeding. Endoscopically in 50% of all cases mucosal ulcerations can be observed. The other cases are non-ulcerous lesions with uncharacteristic endoscopical findings. The majority of the lesions are within 6-8 cm of the anal margin. In 44% of the patients there are findings, which are suspicious of preexisting rectal prolapse. The histological main criterion is a fibromuscular hyperplasia of the lamina propria. Full agreement of endoscopical and histological diagnosis at primary examination could be obtained in only 17% of the cases.

Adult↗
PubMed1988

[Hyperplasiogenic polyps and risk of stomach cancer].

In 731 hyperplasiogenic polyps which have been removed by endoscopical polypectomy there were 9 polyps with an early cancer and 8 polyps with severe dysplasias (borderline lesions) as well as 1 polyp, in which an advanced carcinoma has been developed. This is the outstanding greatest number of hyperplasiogenic polyps with a malignant transformation. In addition in 9 patients with hyperplasiogenic polyps carcinomas could be discovered, i.e. a rate for malignant developments of 3.7%. It seems that stomachs with multiple polyps are endangered in particular. The recurrence rate of follow-up examinations covering a period of up to 8 years was 36.1%.

Cell Transformation, Neoplastic↗
PubMed1987

[Intraoperative peroral endoscopy and vague sources of bleeding in the jejuno-ileum].

Although bleedings in the part of the jejunoileum only amount to about 1% of bleedings of the whole gastrointestinal tract, they can raise outstanding problems because of the difficulties in discovering the sources of bleeding and their localization. The importance of intraoperative endoscopy will be emphasized by example of 5 patients who suffered from recurrent bleedings. All of the other diagnostic procedures like x-ray examinations (angiography included), endoscopy and scintigraphy were fruitless.

Adult↗
PubMed1986

[Alcohol induced damage to the pancreas in patients with increased blood alcohol levels detected in road traffic].

50 patients, driving motor-cars, having increased blood alcohol levels, were registrated and prosecuted. They voluntary underwent catamnestic researches for early diagnosis of alcohol induced lesions of the pancreas. In relation to the habitual drinking systems the study concluded 28 (56 per cent) healthy persons, 13 (26 per cent) alcohol endangered cases, 9 (18 per cent) alcoholics. Various biochemical parameters were changed, liver histomorphology resulted in about 50 per cent of cases a fatty degeneration of the liver and hepatitis. Special diagnostic methods (CCK-test, ERCP, ultrasound echography, computer-tomography) submitted in 24 per cent of cases suspect of alcohol induced pancreatitis. Results, which promote alcoholic pancreatic damage, are being discussed.

Adolescent↗
PubMed1985

[Causes of gastrointestinal hemorrhages in chronic liver diseases].

356 patients with chronic liver diseases hospitalized in our clinic during the period from January 1, 1981, to December 12, 1983, were enrolled in a retrospective study. Of them 55 had been admitted for acute gastrointestinal hemorrhage. It appears that gastroscopy is the only method allowing to localize the origin of the bleeding with high certainty. Bleedings from varices (45%) and ulcers or erosions (22%) were seen most frequently. With regard to case history, clinic, paraclinic and prognosis, no significant differences were found between these various origins of the hemorrhages. Also it is remarkable that all bleedings occur with higher frequency in portal hypertension.

Adult↗
PubMed1985

[Emergency endoscopy in chronic liver diseases].

Emergency endoscopy has to be regarded as a method of high diagnostic value. Based on the resulting therapeutic consequences and with allowance for the prerequisites and contraindications, emergency endoscopy in chronic liver diseases is to be considered a purposeful method. If endoscopic treatment possibilities in bleedings of the gastrointestinal tract continue to improve, the demonstration of an improvement in prognosis by emergency endoscopy seems to be merely a question of time.

Duodenal Ulcer↗
PubMed1985

[Effect of Visotrast (R) and bilirubin on lipase and alpha-amylase activities of pancreatic secretions].

The contamination of pancreatic juice obtained by endoscopic retrograde catheterism of the papilla by cannulation of the pancreatic duct with contrast medium is possible. When the amount of "VisotrastR 370" is more then 0.05 ml per ml one observes a decrease of the lipase while alpha-amylase is unchanged.--Bilirubin has also an influence on the activity of lipase - but not on the alpha-amylase.

Bilirubin↗