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Biomedical subjects

H Brüster

Publications and source records attributed to H Brüster.

At least 19 recordsLinked to original sources
PubMed1985

[Autotransfusion in aneurysm surgery].

In a group of selected 65 patients undergoing replacement of the thoraco-abdominal (TAA = 16) or abdominal (AAA = 49) aorta for large aneurysms intraoperative autotransfusion with the cell saver was used to salvage the patients' blood. The mean volumes of retransfused red blood cells were 1.21 (AAA) and 3.61 (TAA) respectively. Mean values for heparin, protein and hemolysis within the last sample of the autotransfused blood were 0.16 IU/ml, 1.24 g/l and 89.5 mumol/l respectively. T1/2 using chrom51 was 21 days. Our results confirm that intraoperative autotransfusion is a valuable and save adjunct in major vascular surgery.

Aorta, Abdominal↗
PubMed1981

[Retinal findings in thalassemia (author's transl)].

Two patients had neovascularizations, bleeding and enclosed vessels or pigmented foci on the retina. The analysis of the hemoglobin showed a raised HbA2 fraction, indicating that they could be considered heterozygous gene carriers of beta-thalassemia. An electrophoretic-spectrophotometric method of determining the hematologic changes is described by means of which thalassemia minima can be diagnosed reliably.

Diagnosis, Differential↗
PubMed1980

[Post-transfusion hepatitis: can the problem be solved today? (author's transl)].

Among 333 patients followed-up after surgery involving a heart-lung machine between 1975 and 1976 seven (2.1%) fell ill with hepatitis. Only in two of them (0.6%) hepatitis B had occurred, caused by HBs-antigen positive blood which had had to be given for a vital indication without testing beforehand. This low rate of disease must now be considered preventable, as in 1975, the time of the transfusions, blood donor control had not reached present-day perfection due to the short period of use of radioimmuno-assay (RIA). In two patients (0.6%) non-B hepatitis following transfusion cannot be excluded although in one patient use of PPSB may be responsible for the disease. Among the 3 other hepatitis cases no aetiological connection between hepatitis and transfusion could be established on the grounds of the incubation period.

Extracorporeal Circulation↗
PubMed1980

[Post-transfusional hepatitis B: a solvable problem? (author's transl)].

Forty-four patients with haemophilia A or von Willebrand-Jürgens syndrome were followed for three years. They received about 28 000 cryoprecipitate produced in the author's laboratories, without a single case of hepatitis B. There were seven among these patients who had no antibodies against surface antigen: they had received a total of 2533 cryoprecipitate. There were no seroconversion or transaminase changes in comparison with values before cryoprecipitates.

Aged↗
PubMed1980

[Diagnosis of the Paget-von Schroetter syndrome and monitoring of the therapeutic results (author's transl)].

Streptokinase or Urokinase can lead to complete healing in Paget-von Schroetter Syndrome. This tyne of lysis therapy should be instituted immediately or after the fourteenth postthrombotic day. The diagnosis should be verified by armphlebography. The therapeutic results must be controlled by phlebography in order to point out the need for continued therapy in case of thrombotic residual.

Axillary Vein↗
PubMed1979

Frequency of hepatitis B after open heart surgery: a retrospective study over a three-year period (1974--1976).

In spite of intensive efforts to reduce the risk of hepatitis B after heart operations, this complication is observed in 40 % or more of the cases. Over a period of three years (1974--1976) we examined 588 patients who had undergone open heart surgery. The following results were found: In 1974 the hepatitis frequency was 2.0 %, while in 1975 and 1976 it was 0.6 % hepatitis B and 0.6 % non-B hepatitis. We believe the reason for this improvement is a more careful selection of blood donors and their continuous control according to the following parameters: regular clinical observation; regular chest x-ray; determination of BSR, hemoglobin and aminotransferase; TPHA test; and search for antibodies. In 1974 hepatitis-B-surface-antigen (HBsAg) was detected by means of reverse hemagglutination tests. Since 1975 a modified radioimmunoassay has been used for this purpose. No donor blood with abnormal results was transfused, except for a very small number of extreme emergencies. The good results demonstrated can only be obtained by following the described program and by strictly avoiding pool preparations.

Alanine Transaminase↗
PubMed1976

[New aspects in the treatment of pneumonitis (author's transl)].

Two groups of patients suffering from pneumonitis received different treatments and were compared retrospectively. The first group (38 patients) was treated with heparin and aprotinin. The overall mortality was 50 percent; of the patients who were artifically ventilated 64 percent died. The second group (60 patients) was treated with heparin, fresh-frozen plasma, nicotinic acid, methylprednisolone, and alpha-receptor blocking agents. In this group the overall mortality was 26.5 percent and the mortality among the patients who were artificially ventilated was 33 percent. These results lead the authors to feel that the treatment of pneumonitis with aprotinin is no longer indicated.

Adolescent↗