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Biomedical subjects

H Brocard

Publications and source records attributed to H Brocard.

At least 19 recordsLinked to original sources
PubMed1980

[Multicenter, double-blind study of oral acetylcysteine vs. placebo].

The mucolytic activity of acetylcysteine (NAC) was evaluated in a double-blind, placebo controlled, clinical trial performed in three pneumology centres and involving a total of 215 patients with the following diagnoses: 84 acute bronchitis, 95 superinfections of chronic bronchitis, 36 complicated bronchitis in patients with severe chronic respiratory insufficiency. Treatment consisted of 1 sachet of 200 mg NAC t.i.d. for 10 days. Standard antibiotic therapy (amoxycillin 1.5 g/day) was concurrently administered for 7 days. Statistical analysis comparing sputum volume and viscosity, sedation of cough and improvement of PEFR in 108 NAC and in 107 placebo treated patients, showed that NAC was very significantly more effective than placebo. The effect of NAC was negligible in the 36 patients with complicated bronchitis, whereas it was evident and remarkable in patients with acute and chronic bronchitis.

Acetylcysteine↗
PubMed1979

[Partial anomalous pulmonary venous drainage of the left lung into the innominate vein (author's transl)].

From 5 cases of partial anomalous pulmonary venous drainage of the left lung into the innominate vein, it has been thought of interest to situate this type of venous anomaly among the partial anomalous pulmonary venous drainage classification. It is revealed in 2 different ways. In adults, this malformation sets the problem of the diagnosis of an abnormal chest Xray, without symptom. In children, this vascular abnormality is discovered during the exploration of a congenital cardiopathy which causes the main symptoms. Embryological data are reviewed and statistics of frequency which lead to show that this type of partial anomalous venous drainage is often misunderstood, particularly with regard to anomalous venous drainage of the right lung.

Adult↗
PubMed1979

[Cutaneous, subcutaneous, and lymph node cryptoccosis in a patient with sarcoidosis (author's transl)].

An Algerien patient aged 31 years with a histologically confirmed mediastinopulmonary sarcoidosis had a persistent stable miliary pulmonary x-ray image after cortisone therapy. Eighteen months after stopping the corticotherapy, he developed cryptococcosis which was mainly cutaneous, but associated with subcutaneous abscesses and peripheral adenopathy, and without lesions in the viscera or deep nodes. Cryptococcus antigens were present in the serum and there was a humoral and cellular immunity reaction towards the cryptococcus. Recovery occurred after amphotericin B and 5-fluorocytosine.

Adult↗
PubMed1978

[Abnormal partial pulmonary venous return of the left lung in an adult (author's transl)].

The authors report a case of left-sided abnormal partial pulmonary venous return. This abnormality was discovered following weight loss with a strongly positive tuberculin skin test. A plain chest X-ray showed an externally convex opacity filling the aortico-pulmonary space, suggestive of a lymphadenopathy in that area. Pulmonary angiography and selective opacification of the different afferent branches of this abnormal vein defined the territory of drainage of this A.P.V.R.

Adult↗
PubMed1978

[Clinical study of pleural fibromas].

After 3 personal observations of pleural fibromas, 67 analogous cases have been recorded. Clinical, radiological and pathological signs are recalled. The authors stress the 2 points which can turn this benign tumour into a serious disease :--onset of major hypoglycemia,--recurrences happening in a malignant fashion.

Adult↗
PubMed1978

[Isolated cystic lymphangioma in the mediastinum].

Cystic lymphangioma localized only in the mediastinum is a rare type of primitive tumour (less than 1% of the mediastinum primitive tumours). These three new observations concern lymphangiomas with an anterior position ; therir anatomical connections with the lymphatic system are difficult to show. Treated by surgery these benign tumours have a good prognosis and only a few cases of local recurrences have been reported.

Adult↗