PubMed Health⌕ Search

Biomedical subjects

H Bujar

Publications and source records attributed to H Bujar.

At least 19 recordsLinked to original sources

[Contrast medium persistence in lymph nodes as a prognostic criterion in Hodgkin's disease (author's transl)].

The persistence of contrast medium in the inguinal and retroperitoneal lymph nodes was observed in 104 cases of Hodgkin's disease. Systematic observations were continued until the contrast medium had disappeared completely. The maximum period of observation was 36 months. The following conclusions were reached: a) There is a difference in the behaviour in the contrast medium in normal and abnormal lymph nodes. b) There is a difference in behaviour between various groups of lymph nodes in patients with negative lymphographic findings. c) In patients with positive lymphographic findings the behaviour of the contrast medium varies depending on the histology and radiological appearances of the lymph nodes. An attempt to correlate the persistence of contrast medium with survival time has shown that there is a shorter period of survival in those patients in whom the contrast medium disappeared most quickly from the abnormal nodes. The persistence of contrast medium in the lymph nodes should be borne in mind during treatment planning.

Contrast Media↗

[Lower limb lymphography where there is no lymph circulatory disorder. Normal conditions and their limits (author's transl)].

Further lymphangiography for the lymphatic system dependent on the internal saphenous vein carried out on 70 patients to establish a lymphographical record of the pelvi-abdominal ganglia, simplified the counting of opacified vessels, and assessment of the development of the vascular system and the fragility of the walls and their calibre and pathway. The various aspects were assessed in relation to the anatomical situation (leg, thigh), age group and sex of the patients. Computerised analysis of the information lead to the conclusion that, even under normal conditions, there are statistical differences in the number of opacified vessels in the legs and in vascular fragility of the pre-inguinal region according to age group. The authors discuss the implications of the limits of the normal appearance of the lymphatic vessels.

Adult↗

Familial clustering of degenerative cardiovascular diseases.

In two geographical areas; the Gurghiu Valley, in a mountain region, and the village of Jurilovca on the shores of the Razelm lagoon, investigations were performed in 390 subjects of both sexes over 20 years of age, first degree relatives of healthy index subjects (males aged 40 to 60 years) and 298 subjects of both sexes over the of 20, first degree relatives of index-subjects with coronary heart disease and/or hypertension. The prevalence of these diseases was found to be 40% higher in the families of diseased subjects. The authors assume the participation of a genetic factor in the etiology of these two degenerative cardiovascular diseases.

Adult↗

Clinical evolution, histologic type and general lymphographic picture in Hodgkin's disease.

In 88 patients with Hodgkin's disease the clinical value of the general lymphographic picture (lymphodynamic aspects plus nodal patterns) is analysed. The survival times are also reported according to the different pre- and postlymphographic evolution. Histologic types and prelymphographic therapy are correlated with the general lymphographic picture. The predominance of foamy and/or spotty lymphographic patterns of lymph nodes as well as the lymphatic blockages have a severe prognosis (mean intervals between lymphography and exitus 8.3 and respectively 6.2 months). In such cases lymphocytic depletion represents the most frequent histologic type.

Hodgkin Disease↗

Coronary heart disease and risk factors in some special type collectivities.

Transversal epidemiologic investigations carried out in different populations from several regions of Romania : Gurghiu Valley (lumberjacks from a mountain region), Danube Delta and Razelm lagoon complex (fishermen), and Bucharest have shown that, in spite of the high caloric value of food and even of a high intake of saturated fats, mean serum cholesterol is lower in the rural areas than in Bucharest, probably owing to the strenuous physical work. However, except myocardial infarction, more frequent in the urban than in the rural regions, the other forms of coronary heart disease have a relatively higher frequency in villages, particularly atrial fibrillation and ECG signs of ischemia. These findings might be explained by a greater prevalence of hypertension in these populations. It is concluded that the risk factors, which act synergically, depend on the complex structure of the "ecologic niche".

Adult↗

Lymphographic aspects of the barrier function of lymph nodes in Hodgkin's disease.

The persistence of Lipiodol in various lymph node groups was followed up by systematic lymphographic control. Assuming a certain relationship between the barrier function of the lymph nodes and the persistence of their image on the film the authors have tried to find out whether the duration of Lipiodol persistence may be a test for the estimation of prognosis in Hodgkin's disease. The observation of such cases has shown that Lipiodol is retained for a longer period in the external iliac and lombo-aortic lymph nodes as well as in the pathologic ones, except those with lymphocyte depletion, whereas it is very rapidly eliminated from the inguinal nodes. These findings seem to prove that Hodgkin's disease is more severe in patients in whom the barrier function of the lymph nodes is defective i.e. unable to retain the foreign substances introduced in the organism. These conclusions should be further verified by comparison with other clinical and biologic factors.

Hodgkin Disease↗