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Biomedical subjects

H C Black

Publications and source records attributed to H C Black.

16 recordsLinked to original sources
PubMed1979

Surgical treatment of hyperparathyroidism.

Hyperparathyroidism, as seen by a single group of surgeons in a community of 320,000 is reviewed in a retrospective fashion. It was shown that symptomatic hypocalcemia could occur up to 110 hours postoperatively and was most likely to occur in individuals showing skeletal demineralization preoperatively. Though large doses of calcium were required postoperatively in three patients, permanent supplementation was not necessary in two of them. Five of seven patients operated upon for secondary hyperparathyroidism received little or no benefit, stimulating critical review of the appropriate indications in this patient population. Mechanical suction proved to be clearly superior to passive drainage.

Adenoma↗
PubMed1979

A comparison of the intradermal and subcutaneous routes of influenza vaccination with A/New Jersey/76 (swine flu) and A/Victoria/75: report of a study and review of the literature.

A trail of influenza vaccination, with use of bivalent split virus vaccine (A/New Jersey/76 and A/Victoria/75), was conducted to compare the immunogenicity and reactions when vaccine was given by the subcutaneous and intradermal routes. Volunteers 18 to 24 years old were randomized into equal groups, one group receiving 0.1 ml of vaccine intradermally and the other receiving 0.5 ml subcutaneously. For the A/Victoria vaccine, the immunogenicity of the intradermal route seemed superior; for A/New Jersey vaccine, the routes were equivalent. Adverse reactions were minimal and equivalent for both groups. In times of vaccine shortage, the intradermal route is considered to stretch vaccine supplies. Field trials of new influenza vaccines should include evaluation of the immunogenicity of and adverse reactions caused by the same vaccine given by different routes in varied dosages.

Adolescent↗
PubMed1977

Influenza in New Jersey in 1976: isolations of influenza A/New Jersey/76 virus at Fort Dix.

An outbreak of febrile respiratory disease at Fort Dix, New Jersey, beginning in January 1976, yielded five isolates of influenza A/New Jersey/76 virus and 42 isolates of strains resembling influenza A/Victoria/75 virus. Despite extraordinary efforts and the study of 305 verified cases of infection with type A influenza virus throughout the region, no additional instances of infections with influenza A/New Jersey virus were detected in humans.

Humans↗
PubMedDate not supplied

Hepatitis B e antigen in volunteer and paid blood donors.

Sera from 200 volunteer donors and 200 paid blood donors, all positive for hepatitis B surface antigen (HBsAg), were tested for the presence of hepatitis B e antigen (HBeAg).HBeAg was detected in 31 HBsAg-positive paid donors (15%), and in 11 HBsAg-positive volunteer donors (5%) by agar gel diffusion. The presence of HBsAg was associated with higher titers of HBsAg. No significant difference was found in the prevalence of antibody to HBeAg (anti-HBe) in the two donor groups. Rheumatoid factor was not associated with the presence or absence of HBeAg or anti-HBe, indicating that HBeAg is probably not an anti-IgG. These data support the epidemiological evidence that paid blood donors appear to be more likely than volunteer donors to transmit hepatitis B virus infection to recipients of their blood.

Aging↗
PubMedDate not supplied

The consequences of administering blood pretested for HBs Ag by third generation techniques: a progress report.

Elimination of commercial blood, mandatory HBs Ag testing by third generation techniques, and detection and interdiction of incriminated blood donors have all contributed to a dramatic 63 per cent reduction in the estimated number of cases of transfusion-associated hepatitis from 424 in 1970 to 158 in 1973 and an even more dramatic drop in fatalities from 55 to 1970 to 10 in 1973.

Blood Donors↗