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Biomedical subjects

H C Burry

Publications and source records attributed to H C Burry.

At least 55 records · Page 3Linked to original sources

A double-blind cross-over trail of Prenazone and aspirin in the management of rheumatoid arthritis.

A double-blind cross-over trial of Prenazone 600 mg and Aspirin 4 g daily was carried out on 20 patients suffering with rheumatoid arthritis. The analgesic and anti-inflammmatory activity was indistinguishable from that of aspirin under the conditions of the trail. Twelve patients expressed a general preference for Prenazone and six for aspirin. Prenazone appeared to be well tolerated and free from serious side-effects. These results suggest that it will be a useful drug in the management of rheumatoid arthritis.

Aged↗

The use of beta-N-acetylglucosaminidase excretion to investigate renal disease in rheumatoid arthritis.

Urine levels of the lysosomal enzyme beta-N-acetylglucosaminidase have been measured in patients with arthritic disorders; significantly higher levels were found in patients with rheumatoid arthritis (mean: 332.9 nmol/h/mg creat.) than in those with degenerative joint disease (mean: 86.31 nmol/h/mg creat.; P less than 0.001). Analysis of the results shows that salicylates were responsible for some of this difference, but suggests that rheumatoid disease itself may cause renal damage.

Acetylglucosaminidase↗

Vasculitis with alclofenac therapy.

Three patients developed a vasculitis while taking alclofenac. Two recovered with corticosteroid therapy, and the third, who had continued to take the drug for a further week despite epistaxis, haemoptysis, haematuria, and cutaneous vasculitis, developed a more persistent vasculitis with histological evidence of progressive renal involvement.

Aged↗

Extradural corticosteroid injection in management of lumbar nerve root compression.

The effect of extradural corticosteroid injection in patients with nerve root compression syndromes associated with degenerative disease of the lumbar intervertebral discs was assessed in a double-blind controlled trial on 100 consecutive inpatients assigned by random allocation to treatment and control groups. Assessment during admission and at three months revealed statistically highly significant differences in respect of relief of pain and resumption of normal occupation in favour of the group treated by extradural injection. This treatment seems to be a valuable adjunct to the management of lumbar nerve root compression syndromes associated with degenerative disc disease.

Anesthesia, Epidural↗

Orudis in management of rheumatoid arthritis and osteoarthrosis of the hip: comparison with indomethacin.

In double-blind cross-over studies in 46 patients with rheumatoid arthritis and in 42 patients with osteoarthrosis of the hip, Orudis-a new non-steroidal anti-inflammatory agent-has been shown to be well tolerated and to have comparable therapeutic efficacy with indomethacin when given in equal dosage. Side effects were less severe with Orudis. The results suggest that Orudis will prove valuable in the clinical management of rheumatic diseases.

Adult↗