Biomedical subjects
Publications and source records attributed to H C Friederich.
A simplified technique of atraumatic tape-suture wound closure was performed by means of horizontal and vertical fixation of Squibb Dermahesive strips along and upon the wound margins; this method was combined with various suture techniques (i.e. interrupted sutures, vertical mattress sutures, half buried/mattress sutures, subcuticular and subcutaneous sutures).
In a prospective clinical study we have investigated the relevant non-compliance variables with 96 patients affected by onychomycosis, who underwent a combined treatment of nail abrasion and application of a topical antifungal. The patients' non-compliance amounted to 24% of the complete group examined. Significantly this occurred more frequently with men (31.6%) than with women (12.8%), and also more frequently with older women than younger women. It occurred with 42% of the male and female pensioners and with 43% of the students. Furthermore, the group of non-compliance patients, in addition to their onychomycosis, frequently exhibited other illnesses requiring treatment in greater degree than the compliant patients. Additional rising variables, e.g. in the seriousness of the clinical outbreaks on the nails and the number of mycotic nails, did not contribute to an explanation of the differences in compliance behavior of the patients. By careful observation of the compliance factors in relation to specific illnesses, a more favorable set of conditions should be achieved in future for the improvement of patient behavior.
63 transcutaneous measurements of oxygen pressure and 36 series of infrared thermograms in 9 hypoxic wounds showed that topical administration of tetrachlorine decaoxide (TCDO) results in increased oxygen supply of the wound. This effect is associated with improvement of the skin temperature and decrease of the pathological temperature difference between the wound and the surrounding tissue. TCDO can induce physiological wound healing, since it improves the mechanisms of the immune defence system, wound cleansing, granulation, and epithelialization in slow-healing wounds.
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The simultaneous presence of psoriasis and atopic dermatitis was checked for in 1065 patients with psoriasis and was found in 18 of them (1.7%), which is in keeping with the statistical probability. In these 18 the efflorescence was also examined histologically. All 18 (100%) reported marked pruritus; white dermatographism was observed in 16 patients (89%); in 15 patients (83%) psoriatic phenomenas could be produced, and 11 patients (61%) also had allergic rhinitis or bronchial asthma. Immunologically, 16 of the 18 patients (89%) showed elevated IgE levels, the geometric mean level being 888 IU/ml. The HLA-Cw6 was positive in 9 patients (50%).
A simple, easy and effective wound closure following dermabrasion was carried out by fixation of Transite over the Epidermal-cutaneous defect and Allevyn over this Mesh-Graft-Like biologic dressing. Transite shows very little adherence to the wound surface. It is not damaging the wound at removal. The dressing removal is painless.
A simple, easy and effective woundclosure following dermabrasion was carried out by fixation of Transite over the Epidermal-cutaneous defect and Allevyn over this Mesh-Graft-Like biologic dressing. Transite shows very little aderence to the wound surface. It is not damaging the wound at removal. The dressing removal is painless.
If the skin is not cooled, dermabrasion induces local hyperthermia of 36 to 41 degrees C. This temperature goes down again after one minute and is not considered the cause of postoperative hypertrophic scarring. Yet, cooling of the skin during dermabrasion is generally recommended. In small as well as in large excoriated areas, high speed dermabrasion causes a temperature decrease (delta T) of about 2 to 3 degrees C due to the evaporation of exudate. If we assume that the vascular capillary plexus in the stratum papillare is seriously damaged, the subsequent reparation of the upper skin layers must be clinically and thermographically interpreted as wound healing (latent and proliferative period). The exothermic reaction of the early phase of wound healing is superimposed by the cooling effect due to exudation. The covering of the skin defect with the fine-meshed polyvinyl alcohol hydrogel polyester netfoil, Cutinova, seems to have a favorable influence on the wound healing process, if the covering is regularly changed every one or to days. This may be due to the temperature increase caused by the prevention of the evaporation of the exudate. Measurements of sensitivity (to pressure, temperature, and pain) showed that the cutaneous sensation almost completely recovered after about 15 days.
Clinical application of thermovision in dermatology is a non-contact, sterile, and absolutely harmless method and offers a variety of diagnostic and therapeutical possibilities regarding the detection of irregularities in the temperature distribution of the skin. Thermovision provides us with information about the extent of dermatoses or tumors, metastases, as well as the response to therapy. Another important medical application of thermovision is dynamic testing in dermato-surgery. This technique is fundamental with regard to diagnosis, management planning, differential diagnosis, monitoring of therapeutical effects, and as a very sensitive detector of recurrence. We are going to demonstrate the applications mentioned above on the basis of a few examples.
We give a survey on the present situation regarding the methods and indications of punch biopsy as well as similar operations, including the design, orientation, and execution for the repair of small skin defects.
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A method of atraumatic wound closure published by Ambroise Pare [1] was carried out by suturing of crosstrips (Mefix-Mölnlycke) fixed along and upon the wound margins, combined with intradermal continuous sutures (absorbable monofilament polydioxanone--4-0, Ethicon).
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Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
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