Biomedical subjects

H C Kuijpers

Publications and source records attributed to H C Kuijpers.

21 records · Page 2Linked to original sources

PubMed1985

Is prophylactic abdominal irrigation with polyvinylpyrrolidone iodine (PVPI) safe?

In order to investigate the safety of abdominal irrigation with polyvinylpyrrolidone iodine (PVPI), the abdominal cavities of normal rats were irrigated with the highest nonlethal dose. Samples of the peritoneal fluid were taken before and 1, 2, and 4 hours after irrigations. Control studies were done with saline. After irrigation with PVPI, the protein concentration in the peritoneal fluid showed a 40-fold increase, compared with only a doubling after saline irrigations. Irrigation with PVPI causes serious peritoneal damage, and should therefore not be performed as a prophylactic procedure.

Abdomen↗

PubMed1984

Diagnosis of disturbances of continence and defecation.

Defecography was performed in 60 patients with disorders of continence or defecation in whom previous investigative procedures had not revealed any abnormality that could explain the disorder. A correct diagnosis was made in 47 patients (78%). Defecography appears to be a suitable procedure to detect functional disturbances of defecation. Since anterior rectal wall abnormalities such as colitis cystica profunda and solitary rectal ulcer were seen in eight patients, it is suggested that these abnormalities are a result of functional disorders of defecation. Furthermore, the function of the pelvic floor musculature can be assessed by defecography in order to determine the cause of fecal incontinence.

Adolescent↗

PubMedDate not supplied

Treatment of complete rectal prolapse: to narrow, to wrap, to suspend, to fix, to encircle, to plicate or to resect?

Selection of the best surgical procedure for the treatment of complete rectal prolapse is difficult amid the many different techniques for which excellent results are reported. A critical review is given. It is concluded that any surgical procedure with rectal mobilization and fixation as a standard maneuver will lead to a recurrence rate of 2% to 4%. Advocacy of additional maneuvers to make the procedure easier is acceptable if it does not lead to a higher complication rate. But to obtain a better result its benefit has to be proven, either by a large prospective double-blind study, or by tests from the colorectal laboratory. New surgical techniques for rectal prolapse should therefore be based, not only on a low recurrence and complication rate, but also on tests that evaluate the effect of the procedure on fecal continence.

Humans↗