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Biomedical subjects

H C Maier

Publications and source records attributed to H C Maier.

11 recordsLinked to original sources

Recurrent and metastatic pulmonary fibrous histiocytoma/plasma cell granuloma in a child.

A child had a pulmonary plasma cell granuloma/fibrous histiocytoma that recurred after lobectomy in 1952 and required pneumonectomy in 1953, at which time it extended into the mediastinum at the pulmonary hilus. A metastatic nodule was removed from within the diaphragmatic musculature. The long-term favorable outcome suggests a good prognosis after adequate surgical therapy. The possible relationship of fibrous histiocytoma/plasma cell granuloma to modified measles is discussed.

Child↗

Neuroendocrine carcinoma of lung associated with bradycardia and episodic cardiac asystole.

A neuroendocrine carcinoma of the lung associated with bradycardia and episodic cardiac asystole is reported. Cardiac dysfunction may have been caused by a hormonal factor produced by a carcinoma developing in the pulmonary neuroepithelial bodies because the bradycardia and periods of asystole disappeared after pneumonectomy, only to return months later when pleural metastatic tumor developed. No neoplastic involvement of the heart was present. Implications of a cholinesterase isoenzyme involvement in the cardiac dysfunction are discussed.

Bradycardia↗

Craniopharyngioma with erosion and drainage into the nasopharynx. An autobiographical case report.

This physician had a craniopharyngioma which was treated by radiation therapy in 1938, with relief of headaches and return to professional activity. Later, penetration of the tumor through the sphenoid sinus into the nasopharynx resulted in the intermittent drainage over 30 years of cystic parts of the tumor into the nasopharynx and from there to the oropharynx without any meningeal rupture. Radiation therapy was the initial mode of treatment, later combined with steroid and thyroid replacement therapy. A professional career was possible in spite of the patient's health problems.

Adult↗

Mediastinal lymph node hyperplasia, hypergammaglobulinemia, and anemia.

An adolescent girl with retarded development, delayed puberty, and hypergammaglobulinemia had anemia unresponsive to iron therapy that was cured when a mass of mediastinal giant lymph node hyperplasia was removed surgically. Rapid growth and development of secondary sexual characteristics occurred after operation. Follow-up studies made 20 years after operation showed compensated increased erythrocyte hemolysis and increased serum IgM. When mediastinal giant lymph node hyperplasia with abundant plasma cells is seen in childhood, there may be refractory anemia and immune disturbances. Similar giant lymph node hyperplasia without plasma cells may be found in an asymptomatic child or adult. The pertinent features of the few symptomatic cases reported are reviewed.

Adolescent↗