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H C Stam

Publications and source records attributed to H C Stam.

10 recordsLinked to original sources
PubMed1985

Implications of lung corrections for dose specification in radiotherapy.

The influence of taking into account the lung density in the calculation of the dose distributions was examined for a group of 23 patients with bronchus carcinoma. Anatomical information and electron densities were available by means of CT scans. All calculations were made for cobalt-60 gamma rays using a patient specific multiple field irradiation technique. The effect of lung tissues for the dose distributions was calculated using a generalization of Batho's method. All patients entered into this study were planned to receive a minimum tumor dose of 60 Gy, calculated without correction for lung density. The actual dose in each patient was recalculated with lung correction. In the group of patients the corrected minimum tumor dose varied between 63 Gy and 77 Gy (105-128%). The calculated homogeneity of the dose in the target area and the dose to surrounding normal tissues are also affected by lung correction. For different radiation techniques and different methods of dose specification, the interrelation between corrected and uncorrected dose is presented in tables. The impact of lung correction on the uncorrected dose schedules that are commonly used in the treatment of patients with lung cancer is discussed.

Carcinoma, Bronchogenic↗
PubMed1972

Curative radiotherapy in Hodgkin's disease: significance of haematogenous dissemination established by examination of peripheral blood and spleen.

Studies of peripheral blood leucocyte concentrates in patients with Hodgkin's disease showed two types of cells believed to be typical for the disease in a number of patients. Involvement of the spleen as diagnosed after splenectomy and histological examination showed a close correlation with the presence of these characteristic cells in the peripheral blood. This is believed to be an argument for haematogenous spread or a multicentric origin of the disease in these cases. The results of attempted curative high-voltage radiotherapy with total node irradiation in 24 patients seem to support this concept. On the basis of the Rye classification of clinical stages the results of radiotherapy are not predictable. Six patients in stage II and seven in stage III were in remission, one in each of stages II and IV, and six in stage III had recurrences of the disease within one year. A division into localized or disseminated forms of the disease based on the investigations of blood and spleen showed all localized cases in remission; of the disseminated cases one reached a remission and all others had recurrences. In three patients the therapy could not be completed. These preliminary treatment results are believed to support the idea of a special role of the spleen in the dissemination of the disease. A new classification of clinical stages in Hodgkin's disease is proposed.

Biopsy↗
PubMed1969

Preface.

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Thermography↗