Biomedical subjects
H Charlanne
Publications and source records attributed to H Charlanne.
Large granular lymphocyte leukaemia associated with systemic sclerosis.
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[Diabetes: a public health menace at the dawn of the 21st century--about the Symposium of the Cardiology and Sports Club organized in Bruges on June 9, 2004 at the time of the 50th French Congress of Internal Medicine "Shock and happiness of Mr. D..., type 2 diabetic"].
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[Celecoxib induced toxiderma with positive patch-test].
INTRODUCTION: Celecoxib (Celebrex(R)) is a new generation non-steroidal anti-inflammatory drug, recently introduced in France. We report a maculopapular rash due to this drug with positive patch-tests. CASE REPORT: A forty year-old man received with 3 tablets/day of celecoxib for intercostal pain. Nine days after initiation of treatment a maculopapular rash appeared. At the end of treatment, the eruption persisted for two days, then rapidly improved within one week. Six weeks later, patch-tests with celecoxib diluted at 20 p. 100 in petrolatum were positive at 48 hours. DISCUSSION: Cutaneous reactions due to celecoxib are rare. In our case report, the delay, clinical aspect, improvement on withdrawal of treatment and positive patch test all emphasize the imputability of celecoxib. We wish to underline the possible cutaneous reactions with this new non-steroidal anti-inflammatory drug.