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Biomedical subjects

H Cremer

Publications and source records attributed to H Cremer.

At least 19 recordsLinked to original sources
PubMed1989

[Malignant blue nevus].

In a 6-year-old boy, we found a malignant blue nevus with metastases of the lymph nodes. After surgical therapy under melanoma conditions, he was treated with interferon. Up to now (2 years after therapy), the follow-up examinations have been negative.

Buttocks↗
PubMed1985

[Malignant fibrous histiocytoma of the prostate capsule].

This report deals with the clinical, ultrasonographical, computertomographical and morphological aspects of the rare malignant fibrous histiocytoma of the prostatic gland. A 80-year-old patient suffered from a fast growing painless tumor of the prostatic area, which, on microscopical examination, proved to be a malignant fibrous histiocytoma. The patient refused surgical treatment and died several weeks thereafter. On autopsy no metastases were found. The diagnosis of a malignant fibrous histiocytoma of the prostatic gland can only be made on microscopical grounds. The differential diagnosis includes a pleomorphic rhabdomyosarcoma or a pleomorphic liposarcoma. The clinical differential diagnosis includes, first of all, a carcinoma of the prostatic gland. Surgery is the therapy of choice. The prognosis of the malignant fibrous histiocytoma of the prostatic gland is poor.

Aged↗
PubMed1985

[Mucoepidermoid carcinoma of the stomach].

A case report is given of a 65 year old female patient harboring a rare mucoepidermoid carcinoma of the stomach. On X-ray examination a smooth faced mass with a diameter of 3 cm was found in the corpus region of the stomach. During gastroscopy the tumor was seen to be localized in the lower third of the stomach close to the lesser curvature with an ulceration on top. On microscopic examination a cornified squamous cell carcinoma was found including interspersed mucilaginous adenocarcinoma tissue. Prognosis of mucoepidermoid carcinoma is bad, histogenesis controversial. Discussion of this case as well as of other unusual adenocarcinomas for example with trophoblastic differentiation has to include the possibility of bidirectional development of undifferentiated stem cells. However it still remains unclear, why such tumors of the stomach are almost always adenocarcinomas and not signet ring cell carcinoma.

Adenocarcinoma, Mucinous↗
PubMed1985

[Segmental chlamydia proctitis].

A case report is given of a 28 year old homosexual suffering from segmental proctitis caused by Chlamydia. The patient had watery diarrhea and fever since 3 weeks. Stool specimen testing was negative in regard to Salmonella, Shigella and worm eggs. Infection with N. gonorrhoea, Herpes simplex virus, Toxoplasma gondi, Yersinia and M. tuberculosis could be excluded. Serological testing yielded results suggestive of an old lues infection successfully treated. On histological examination typical reticulocytary suppurating granuloma were found. Therapy of choice of Chlamydia-proctitis is tetracyclines.

Adult↗
PubMed1983

[Locally aggressive fibrous histiocytoma of the external ear canal].

This article reports on clinical as well as light-microscopical and electron-microscopical findings in a fibrous histiocytoma of the left external auditory canal. The patient, who was then 67 years old, complained of a space-occupying mass in the external auditory canal which resulted in partial deafness. On microscopical examination a 3 x 2 cm large tumour was found to be located at the boundary between the osseous and the cartilaginous auditory canal. The covering skin was intact. On histological examination we identified a moderately cellular, locally aggressive fibrous histiocytoma. To our knowledge, no fibrous histiocytoma of this localisation has ever been reported. The diagnosis can be made on histological grounds only. Differential diagnosis includes, besides a ceruminoma, almost all benign and malignant non-epithelial tumours of the external auditory epithelial canal. Surgical removal is the therapy of choice. One year after the operation there has been no relapse.

Aged↗
PubMed1982

[Thymomas--clinico-pathologic aspects].

A collective of 38 patients with a thymoma, confirmed by microscopic investigation, was analysed retrospectively. 63% of them were female. In 27% of the cases the final diagnosis could be made by autopsy only. 56% of the operated patients lived half of their age-dependant expectation of life. The 5- and 10-year-survival rates amount 84% and 68%, respectively. Of the non-operated patients no one was alive 2.5 years after diagnosis. There was no consistent relationship between the different histologic structure of thymomas (degree of lymphocytic infiltration) and the clinical behaviour and the survival rate. All patients with "parathymic syndromes" were women. One case with pure red cell anemia (erythrophthisis) was associated with spindle-shaped epithelial thymoma. The incidence of myasthenia gravis did not depend on the histologic pattern of thymomas.

Adolescent↗
PubMed1980

[The pathogenesis of spontaneous perirenal haematomas (author's transl)].

This report deals with two cases of a spontaneous perirenal hematoma. In the first case the spontaneous perirenal hematoma resulted from hemorrhages from the vessels of the stratum fibrovasculare of the renal capsule. This bleedings led to the development of a granulation tissue which in turn is rich in small blood vessels. Due to the lytic activities of this granulation tissue the hematomas became resorbed and finally are transformed into a big pseudocyst which surrounds the lower half of the kidney. On the other hand the new-built vessels of the granulation tissue are the source of further bleedings thereby perpetuating the process. In the second case the perirenal hematoma resulted from two aneurysms of the renal artery. In both cases clinical and radiological investigations had been unable to demonstrate the lesion.

Aneurysm↗
PubMed1980

[Histological and cytological criteria for classification of primary liver cell carcinoma (author's transl)].

23 cases of liver cell carcinoma were reclassified according to the WHO classification schema. Appropriate cases could be classified without any difficulty into the trabecular, compact and acinar type groups; there was more difficulty to classify the scirrhous type of carcinoma. Carcinoma composed by clear cells, and inacrocellular eosinophilic carcinoma with lamellar fibrosis have a lower incidence of mitoses than the other carcinoma types. AFP could be demonstrated in tumor tissue by immune histochemistry in one case only; HBs-Ag could never been shown by the aldehyd-thionin method. The ratio mitoses/apoptoses was approx. 2:1.

Adenocarcinoma↗