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Biomedical subjects

H D Christiansen

Publications and source records attributed to H D Christiansen.

4 recordsLinked to original sources
PubMed1990

Risk factors in continuous ambulatory peritoneal dialysis. A seven year follow up.

The purpose of the present study is to assess the mortality rate and the magnitude of technical problems forcing a patient off CAPD and to clarify the effect to which age, sex, diabetes, or cardiac disease influence mortality rate and technique survival. For this purpose, we used estimated survival probabilities by Kaplan-Meier methods. The study of all patients in our department dialysed on CAPD until July 1986 revealed a two-year survival of 63% for 121 patients. Mortality was significantly higher in patients with diabetes or prior cardiac disease. Non-diabetic patients over 60 had the same mortality rate as younger non-diabetic patients. The overall rate of transfer to other forms of dialysis was 35% after two years with little variation between subgroups, suggesting that parameters such as age, sex, diabetes and cardiac disease need not influence the choice of CAPD if based on technical considerations.

Cause of Death↗
PubMed1989

[Peritonitis in continuous ambulatory peritoneal dialysis. Experiences after 7 years].

A retrospective study of CAPD-related peritonitis revealed a frequency of 1.7 episodes per treatment year among 121 patients during a period of 7 years. Life-table methodology estimated a 44% probability of still remaining peritonitis-free after six months on CAPD, with no differences between subgroup populations according to sex, age (younger/older than 60 years) and primary disease (diabetic/non-diabetic). A marked improvement in probability of remaining peritonitis-free was evident in the last calendar period (1983-86). The predominant etiological microorganisms in peritonitis episodes were staphylococci. In 25% of the episodes, no microorganism could be isolated. One patient died from peritonitis; lethality 0.7% per year. Ten patients (8%) were transferred from CAPD because of either repeated episodes of peritonitis or a single complicated episode.

Denmark↗
PubMed1981

Long-term prognosis after transient ischemic attacks.

A retrospective follow-up study of 243 patients with transient ischemic attacks (TIA) is reported. The long-term mortality of the patients was higher than that of the corresponding general population. It is demonstrated that the excess mortality over the whole period of observation, irrespective of the age and sex of the patients, can be characterized by a single figure expressing the slope of the curve obtained by semilogarithmic plotting of the ratios of observed to expected survival against time. The use of this numerical expression--in the present series -0.04--will thus facilitate comparisons of the survival of TIA patients drawn from different populations. Unfavourable prognostic factors were: carotid TIA, associated extracerebral disease, and a history of hypertension. Fatal strokes, being four times as frequent as expected according to published incidence figures, accounted for 20% of the deaths, heart disease 38%. Stroke deaths tended to occur earlier than cardiac deaths. The results support the concept that most TIAs, like strokes, are incidents in the progressive course of a generalized vascular disease. The finding of a constant excess mortality over the years following a TIA makes it difficult to recommend a discontinuation of prophylactic therapy at any particular time.

Age Factors↗