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Biomedical subjects

H D Gründer

Publications and source records attributed to H D Gründer.

At least 19 recordsLinked to original sources

[Importance of differential diagnosis of ringing and splashing sounds in the abdomen of adult cattle].

In cattle liquid and gas in the abdominal cavity can be detected from the outside by use of simultaneous auscultation and percussion or by auscultation with simultaneous shaking of the abdominal wall. Size, area and the quality of the "ping" and splashing sounds are helpful to determine which organs are involved in the disease. Nine possible reasons for intraabdominal gas- and liquid accumulation are discussed. In 12 schematic figures the areas of externally detectable "ping" and splashing sounds are compared with the topographic anatomical situation inside the abdomen.

Abdomen↗

[Clinical and hematological studies in newborn Holstein-Frisian breeding calves with diarrhea in Morocco].

A total of 120 (80 males and 39 females) newborn Holstein-Frisian calves suffering from acute diarrhoea were studied clinically and biochemically, including the following parameters: pH, pCO2, act. HCO3, BE, RBC, PCV, HV, glucose lactate, urea, creatinine, total bilirubin, total protein, AST, Na, K and Cl. The results were interpreted according to their healthy condition, their age as well as their sex. The study had revealed an extreme metabolic acidosis, haemoconcentration, hypoglycaemia and hypofunction in the kidney and liver. Furthermore, the calves with diarrhoea had showed hyponatraemia, hypochloraemia, and hyperkalaemia. Important correlations between clinical and some blood parameters were found. Metabolic acidosis was more severe in male calves than females. These pathophysiological changes should be put in consideration during the therapy of newborn calves suffering from diarrhoea.

Acid-Base Equilibrium↗

[Hemocytological and hemobiochemical studies in black pied, clinically healthy breeding calves in Morocco].

In the following study, normal blood values were performed on 58 Friesian calves (30 males and 28 females) under preexisting Moroccan management conditions. The following parameters were evaluated: pH-value, p.CO2, actual HCO3, BE, BB, RBC, WBC, PCV, Hb, MCV, MCHC, Glucose, lactate, urea, creatinine, total protein, total bilirubin, enzyme activities of AST and GGT and electrolyte-values (Na, K, Cl). The values of all parameters varied significantly with age with the exception of MCV, MCHC and K. The female calves presented higher values of act. HCO3, BE, BB, Hb, PCV and MCV than the male calves (p less than 0.01). The calves were born in mixed acidosis stage which was largely restored 24 hours later. At the weaning, the calves showed a slight metabolic acidosis with a partial respiratory compensation. The metabolic acidosis was accompanied with an increase of lactate level in blood plasma. During the first month of life, the development of an anaemia (PCV decreased) was observed. The mean values of glucose and total protein increased after colostrum intake, whereas the electrolyte values in blood plasma decreased. In general, the mean values of lactate, creatinine, urea, total bilirubin and the activities of AST and GGT decreased with age, while glucose and total protein remained nearly unchanged. The age and the sex should be taken in consideration judging the above mentioned parameters in a new born calf from birth to weaning (here: two months).

Acid-Base Equilibrium↗

[Results of liver function tests in abomasal displacement and ketosis of cattle].

Totally 187 cows were used in this research, 101 of these had left and 60 right abomasal displacement. The rest of them had ketosis. Blood and urine samples were collected from all of the cows for laboratory analyses. The amount of bile acid and total bilirubin and activity of aspartate aminotransferases (AST) in blood samples and the amount of ketone in the urine samples were determined. The results obtained from this study were as follows: The mean value of bile acid, total bilirubin and AST-activity were 38.37 mumol/l, 13.06 mumol/l and 92.26 U/l in right abomasal displacement cows and 37.93 mumol/l, 14.39 mumol/l and 68.39 U/l in left abomasal displacement cows respectively. Although important differences (P less than 0.05) were detected in AST-values between these three groups of diseases, there was no significant differences in bile acid and total bilirubin. There was a correlation between total bilirubin and bile acid and total bilirubin and AST in the right and left abomasal displacement cows. Same correlation was determined between total bilirubin and AST in acetonemic cows. But there was no correlation between total bilirubin and bile acid in acetonemic cows and between bile acid and AST in abomasal displacement and acetonemic cows. A very important connection was determined between the amount of total bilirubin and degree of the acetone in the urine (P less than 0.001) of the left abomasal displacement cows. The same connection (P less than 0.05) was determined between the degree of the acetone in the urine and AST-activity in the same cows.(ABSTRACT TRUNCATED AT 250 WORDS)

Abomasum↗