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Biomedical subjects

H D Mollman

Publications and source records attributed to H D Mollman.

4 recordsLinked to original sources
PubMed1993

Primary pontine hemorrhagic events. Hemorrhage or hematoma? Surgical or conservative management?

The pathophysiology of primary pontine hemorrhagic events is unclear, but the traditional classification of hemorrhage or hematoma does not have either pathologic or clinical support. Reported cases of brain stem hemorrhage suggest that patients who suffer progressive deterioration from hemorrhagic pontine lesions may benefit from surgery even if they eventually become comatose, whereas those who suddenly lose consciousness and have profound neurologic deficit probably will not survive.

Cerebral Hemorrhage↗
PubMed1988

A clinical comparison of subarachnoid catheters to ventriculostomy and subarachnoid bolts: a prospective study.

A subarachnoid catheter (SAC) technique of continuous intracranial pressure (ICP) monitoring is presented and compared to intraventricular catheters (IVC's) and subarachnoid bolts (SAB's) in 40 neurosurgical patients. Thirty-one patients were monitored simultaneously with SAC's and IVC's and nine patients with SAC's and SAB's, and the ICP waveforms and measurements were compared. The duration of monitoring ranged from 15 hours to 11 days, and the initial ICP from 2 to 117 torr. A total of 42 SAC's were placed; two that entered brain parenchyma were redirected. One SAC placement was associated with an intracerebral hematoma. There were no infections. For the 31 patients with SAC's and IVC's, there were 2706 pairs of ICP measurements with a mean difference of -0.12 torr and a standard deviation of 5.29 torr. The waveforms from the SAC's and IVC's were indistinguishable. For the nine patients with SAC's and SAB's, there were 773 pairs of ICP measurements with a mean difference of 1.24 torr and a standard deviation of 32.83 torr. The SAB waveforms were of varying quality and all dampened with time. The paired t-test (ts) demonstrated no statistically significant difference between SAC's and IVC's (ts = - 1.19). An analysis of variance demonstrated the scatter of the measurements obtained from SAB's to be 38.5 times that of SAC's, p less than 0.00005. The SAB is shown to be relatively inaccurate with a wide range of variance, while the SAC is demonstrated to be an accurate, reliable, and safe method of continuous ICP measurement and an acceptable alternative to ventriculostomy.

Adolescent↗
PubMed1986

Risk factors for postoperative neurosurgical wound infection. A case-control study.

A case-control analysis was performed to evaluate the association of 15 potential risk factors with postoperative infection in neurosurgical patients. All infections that developed postoperatively on the neurosurgical service at the University of Minnesota from January, 1970, to March, 1984, were identified. Among the 9202 operations performed during that time, 101 infections occurred for a rate of 1.1%. Three risk factors showed significant association with postoperative infection: cerebrospinal fluid (CSF) leak, concurrent noncentral nervous system (CNS) infection, and perioperative antibiotic therapy. The presence of a CSF leak and a concurrent non-CNS infection increased the estimated relative risk of infection to 13:1 and 6:1, respectively. The use of perioperative antibiotics was associated with a decrease in the risk of infection to approximately 20% of the control level. Three other risk factors (paranasal sinus entry, placement of a foreign body, and use of a postoperative drain) appeared to be associated with increased risk of infection, although statistical significance was not demonstrated. None of the remaining nine risk factors studied showed any suggestion of increased risk of infection.

Adult↗