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H Danner

Publications and source records attributed to H Danner.

At least 37 records · Page 2Linked to original sources

[The cytoarchitecture of the rat globus pallidus].

The globus pallidus of the adult rat was investigated by means of the Golgi-rapid-impregnation technique. The cellular population of the globus pallidus is composed of 4 morphologically different neuron types: 1. Large-sized, spindle-shaped neurons; 2. Large-sized, polygonal neurons; 3. Small spindle-shaped neurons; 4. Small spine-bearing neurons. The large spindle-shaped neurons and the large polygonal neurons are considered to be efferent pallidal neurons; the small spindle-shaped neurons and the small spiny neurons are suggested to be pallidal interneurons. It is possible to adapt the neuron classification presented here to recent imaginations concerning the role of the globus pallidus within the extrapyramidal system.

Animals↗

[Spiny neurons in the rat caudate-putamen complex].

The neostriatum of adult normal rats and of rats after surgical lesion of MFB was investigated by means of the rapid Golgi impregnation procedure. Evidence was given for the spiny neuron population to be heterogenous. It was possible to demonstrate four neuron types clearly distinguishable with respect to size and shape of the soma, dendritic pattern, and axon morphology. The morphological heterogeneity of the spiny neurons of the caudatus-putamen-complex of the rat presented here is discussed in functional terms (interneuron and efferent neuron nature, resp.).

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[Investigation on the cytoarchitecture of the nucleus accumbens septi of rat (author's transl)].

The nucleus accumbens septi of the normal adult rat was investigated by means of the rapid Golgi impregnation technique according to Valverde (1970). 5 neuron types could be differentiated: type 1: spiny neurons; type 2: few spiny neurons; type 3: aspiny giant neurons; type 4: spiny spindle shaped neurons; type 5: aspiny spidery neurons. The types 1, 4 and 5, resp., are considered, with respect to morphological criteria, to represent interneurons, whereas the types 2 and 3 are considered to be accumbens output neurons. The cytoarchitecture of the nc. accumbens septi thus displays striking similarities with the caudate-putamen-complex. An hypothetical correlation of these neurons in a functional -- biochemical sense as well as their position in the nc. accumbens which is suggested to be a transition area between limbic and extrapyramidal motor systems, is discussed.

Animals↗

[Cytoarchitecture of the olfactory bulb of the rat].

The olfactory tubercle of rat was investigated by means of the rapid Golgi impregnation procedure. Based on morphological criteria, seven neuron types can be distinguished in this brain region of adult rat. Two types (pyramidal neurons and large polygonal neurons) are considered to be efferent in nature whereas the other types (spine-bearing fusiform neurons; aspiny fusiform neurons; granule cells; dwarf neurons, and neuroglioform neurons) do, in all probability, represent tuberculum interneurons. It is obvious from impregnation studies done in the olfactory tubercle of very young rats (seven days postsnatally) that neurons are still poorly differentiated at this time.

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[Cytoarchitecture of the nucleus raphe dorsalis of the rat].

The nucleus raphe dorsalis of the rat was investigated by means of the Golgi rapid impregnation technique: a) Type 1 neurons: polygonal neurons with somatic spines. The axons which course towards the ventral tegmental area, there by giving off a few collaterals. b( Type 2 neurons: fusiform neurons the axons of which course in a latero-dorsal direction, emitting a few collaterals, too. c) Type 3 neurons: small pyriform neurons. The axons of these cells do not show any favoured route within the nucleus. The type 1 and type 2 neurons are considered to be efferent neurons having different modes of projection and termination. The type 1 neurons are supposed to represent the 5-HT ergic raphe dorsalis neurons. The type 3 neurons, are in probability, raphe interneurons. The findings presented here are indicative of the nucleus raphe dorsalis of the rat to have a more intricate cytoarchitecture as has been thought previously.

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[Fluorescence histochemical and neurohistological investigations on the nucleus raphes dorsalis of the rat (author's transl)].

The nucleus raphes dorsalis of the adult rat was investigated by means of fluorescence histochemical and neurohistological methods. After application of Falck-Hillarp-technique characteristics 5-HT-fluorescence could be seen in many, albeit not all of the cells of this nucleus. After using the rapid Golgi impregnation technique, 3 neuron types could be demonstrated: type-1-neurons (polygonal neurons with somatic spines); type-2-neurons (fusiform neurons), and type-3-neurons (pyriform neurons). The type-1- and type-2-neurons are, due to their different axon projection mode, considered to be efferent raphe neurons. The type-3-neurons are thought to be raphe interneurons. The type-1-neurons are inferred to represent the 5-HT producing neurons of the nucleus raphe dorsalis.

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[Fluorescence histochemical and neurohistological investigations on the locus coeruleus of the rat (author's transl)].

The Locus coeruleus (LC) of the adult rat was investigated by means of fluorescence histochemical and rapid GOLGI impregantion technique. The majority of LC neurons displayed, as a result of application of the FALCK-HILLARP-technique and the LOREN-technique, resp, the well-known fluorescence typical of catecholamine neurons. There was lack of fluorescence within a minor portion of cells. Fluorescence histochemically, serotoninergic afferents could be shown to go up to noradrenaline-containing neurons in some cases. In the GOLGI material, 3 types of neurons could be distinguished: Polygonal neurons exhibiting somatic spines, fusiform neurons, and small-sized spine-less neurons. Based on morphological features, the polygonal neuron type is considered to represent the monoamine-containing neurons of the Locus coeruleus. It appears uncertain at present to attribute the fusiform and small spineless neuron types in a functional manner. functional implications inherent that morphological heterogeneity have been discussed.

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[Fluorescence histochemical investigations on the topic of GABA and dopamine in the neostriatum of the rat (author's transl)].

In the neostriatum of adult rats the distribution of Dopamine and GABA was investigated by means of fluorescence histochemical methods. There is a different mode of distribution of the transmitters in this brain region. The animals were treated with cycloserin, acting as an inhibitor of the GABA transaminase, in order to enhance the GABA content. In the neostriatum GABA containing neurons and GABA-ergic afferents could be demonstrated. GABA containing fibers are present in the whole striatum. Varicose Dopamine fibers appear as a dense fluorescent network.

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[Notes on the transmitter histochemistry of the cortex cerebelli of rat].

The cortex cerebelli of the normal, adult rat was investigated fluorescence histochemically by means of the paraformaldehyde method according to FALCK and HILLARP (1962) for visualization of catecholamines and a modified ninhydrin-reaction for the demonstration of GABA (PFISTER and GORNE 1978), respectively. The Purkinje neurons were shown to display a considerable variability of the fluorescent GABA reaction product. Noradrenergic boutons were shown to be arranged mostly in a punctate manner around the somata of the Purkinje cells. The Purkinje cell pericarya would thus be under the inhibitory influence of cerebellar bascet neurons as well as of Locus coeruleus neurons.

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[The structure of the neostriatum in the rat].

The neostriatum of the adult rat was investigated by means of the Golgi-rapid-impregnation technique. The fasciculi of the capsula interna which are embraced by the dendrites of the spiny neurons in a rank-like manner represent the structural framework of this brain region. The cellular population of the neostriatum is composed of at least five morphologically different neuron types: 1) Spiny neurons which by far outnumber the other types; 2) Few spiny neurons; 3) Large spiny neurons (giant neurons); 4) Small sized aspiny neurons; 5) Spider shaped aspiny neurons. The spiny neurons (type 1 neurons) and the small sized aspiny neurons (type 4 neurons) are considered to be striatal interneurons; the large sized aspiny neurons (type 3 neurons, giant neurons) and the spider-shaped aspiny neurons (type 5 neurons) are suggested to be striatal efferent neurons. The functional correlation of the few spiny neurons (type 2 neurons) is not possible as yet. A dense fiber plexus extends throughout the neostriatum unubiquitously. The axon type which appears to be distinctive according to morphological criteria - fine varicose axons, so called beaded axons - is supposed to be the terminals of the mesencephalic dopaminergic neurons. The heavily impregnated aggregations which are characteristic of the striatum after using the Golgi-rapid-treatment are thought to represent conglomerations consisting of neurons, glial cells and beaded afferent fibers.

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[Fluorescence histochemistry and neurohistologic studies of the adrenergic innervation of the pyriform cortex in the rat].

The pyriform region of normal adult rats was investigated by fluorescence histochemistry and Golgi-rapid-impregnation technique. Fluorescence microscopically noradrenaline and dopamine fibers could be described in typical arrangement and distribution. It is suggested that various Golgi-"beaded" -axons in the cortex pyriformis may be equivalent to the fluorescence histochemically demonstrated varicose catecholamine axons. This would raise the possibility of interpreting, in the Golgi impregnation technique, kinds of axons in a functional manner.

Adrenergic Fibers↗

[The activities of the transmitter metabolizing enzymes monoamineoxidase and acetylcholinesterase and of succinic dehydrogenase were investigated in the telencephalon of Salmo irideus (teleostei) (author's transl)].

The activities of the transmitter metabolizing enzymes monoamineoxidase and acetylcholinesterase and of succinic dehydrogenase were investigated in the telencephalon of Salmo irideus (teleostei). There is a high reaction intensity of the MAO in the whole telencephalon with graded differences between the various nuclear areas. It is highest in the area dorsalis telencephali; the larger fiber tracts (Tr. olfactorius medialis et lateralis; medial and lateral forebrain bundle) are strong MAO-positive, too. There is an extremely weak AchE-reaction throughout the telencephalon. The only nuclear area which is clearly histochemically demonstrable is the regio Dm2 in the area dorsalis telencephali. The SDH-activity is demonstrable in the whole telencephalon. The activity is higher in the area dorsalis as compared with the area ventralis telencephali. In the ependym there are only a few traces of MAO- and SDH-reaction products. The recent findings may support, from a histochemical view, the hypothesis that the telencephalon of Salmo irideus represents brain structures which show structural and functional similarities with limbic telencephalic structures of higher vertebrates.

Acetylcholinesterase↗

[Morphology of the telencephalon of Salmo irideus (Teleostei). Golgi-impregnation study].

The telencephalon of Salmo irideus (Gibbons) was investigated by means of staining and silver impregnation techniques. It shows the fundamental plan characteristic for teleost species. The neurons in the various telencephalic nuclear areas are, in part, quite different with respect to their density of arrangement,migratory behavior, width of pericaryon and number of spines, inclusively. Neurons exhibiting a high degree of morphological differentiation (i.e. neurons of the stellate and pyramidal like type of differentiation) are located in the area dorsalis telencephali only. This telencephalic region is considered to be a functional homologon of limbic telencephalic structures of other vertebrates.

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[Ependymal structures in the telecephalon of Salmo irideus (Teleostei)].

The ependyma in the region of the telencephalon of Salmo irideus is composed of a great number of various elements: uni- and bipolar tancytes, ependymal astrogliacytes, ciliated ependymal cells, intraependymal neurons and neuron-like cells exhibiting ventricular contact. There are regional differentiations in the ventricular wall which can be attributed to certain structurally defined nuclear areas. When comparing the various regions of the ventricular wall in the telencephalon of Salmo irideus with appropriate regions of amphibians and reptiles, some, at least partially, far-going morphological similarities can be found. The ependymal differntiations could, thus, be regarded as an additional morphological criterium concerning the question of the homologization of the telecephalic nuclear areas with those of other verebrates. The abundnat occurrence of tanycytes of the bipolar type in the telecephalon appeared surprising; they are discussed to act in a preponderantly resorptive manner, as it is, above all, hitherto known for hypothalamic regions of other vertebrates. The morphological and functional characteristics of the neuronlike structures exhibiting ventricular contact are as yet not clear.

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