Biomedical subjects

H Deleu

Publications and source records attributed to H Deleu.

3 recordsLinked to original sources

PubMed1992

The relative importance of the components used for ultraviolet A protection in broad-spectrum sunscreens.

The need for effective ultraviolet A (UVA) protection is increasing. Broad-spectrum sunscreens are being used to protect the skin against aging and in the treatment of photodermatoses, where UVA protection can be vital. They are also used by patients taking photosensitizing drugs, such as 8-methoxypsoralen, to protect their skin against solar UVA. This raises the question of what components in broad-spectrum sunscreens are the most necessary for optimal UVA protection. In the present study, the components that can be used are compared and evaluated using an animal method with the inhibition of skin edema induced by 8-methoxypsoralen plus UVA as the biological end point. The results of this method indicate that powders do not provide any significant UVA protection. This could be due to the use of 8-methoxypsoralen in the test so that particularly the shorter UVA range is evaluated. Powders reflect mainly the longer UVA wavelengths. The UVA protection as measured with this method seems to be similar for the benzophenone derivative and for the dibenzoylmethane derivative. The UVA protection factors obtained are compared with those obtained in human skin using phototoxic erythema and UVA-induced tanning as parameters.

Animals↗

PubMed1991

Airborne contact dermatitis: an update.

This review is an update of a previously published one on airborne-induced contact dermatoses. Because reports in the literature often omit the term 'airborne', 12 volumes of Contact Dermatitis (July 1985-April 1991) were screened, and the cases cited were classified as to history, lesion locations, causative agents, and other factors. The number of reports of airborne dermatoses has increased considerably in recent years.

Air Pollutants↗

PubMed1990

Protecting the eye from ultraviolet A radiation during photochemotherapy.

Except for the skin, the eye is the only organ that is continuously exposed to solar radiation, including longwave ultraviolet irradiation (UVA). Since 8-methoxypsoralen (8-MOP) remains not only in the skin but also in the lens of the eye after 8-MOP + UVA (PUVA) treatment, wearing protective goggles just during the UVA irradiation is insufficient. It is wise to shield the eyes for several hours after 8-MOP ingestion, to avoid or reduce possible long-term side effects such as cataract formation. Adequate eye protection from UVA after PUVA can be provided by sunglasses that filter out the appropriate UVA spectrum from the sunlight. Nearly all the commercially available sunglasses are colored, which reduces the intensity of the visible light reaching the eye. In such cases, the diameter of the pupil can remain dilated, which it would not without sunglasses. However, the UVA intensity remains the same. As a result, more UVA can reach the lens. In this study, new uncolored glasses are evaluated and compared with commercially available sunglasses (all colored) to determine their UVA transmission.

Eye↗