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H Dohi

Publications and source records attributed to H Dohi.

At least 19 recordsLinked to original sources
PubMed1997

Preference of sheep and goats for extracts from high-grain concentrate.

Appetite stimulants were extracted and partially isolated from high-grain concentrate. The stimulants were fed daily and were palatable to sheep and goats used in the experiments. The stimulative effects were tested by comparing the intake of two types of hay: with or without the extracts. Diethylether and n-pentane extracts of the concentrate stimulated feeding in sheep (P < .01 and P < .05, respectively). However, methanol extracts had no significant stimulative effect on selective feeding in sheep. Goats also preferentially fed on hay sprayed with the diethyl ether extracts (P < .01). The diethyl ether extracts were divided into acid, neutral, and basic fractions. Sheep and goats had a marked preference for the acid fraction only (P < .01 and P < .05, respectively). These results suggest that specific chemicals to increase palatability of hay are present in high-grain concentrate and that the chemical are nonpolar, acidic substances.

Animals↗
PubMed1997

Intake stimulants in perennial ryegrass (Lolium perenne L.) fed to sheep.

Few studies exist on intake stimulants in forage plants, although a large amount of research has been conducted on deterrents to the feeding behavior of herbivore livestock. To study intake stimulants in plants, chemical components of perennial ryegrass were extracted, fractionated, and examined for their effects on the feeding behavior of sheep. Methanol extracts were found to be stimulants, and pentane extracts tended to be deterrents. The ethyl acetate fraction of the methanol extracts stimulated feeding, and the basic ethyl acetate-soluble fractions of the methanol extracts were bioactive. These results suggest that the basic and less volatile chemicals in perennial ryegrass stimulate feeding in sheep in the absence of other cues.

Acetates↗
PubMed1997

[A nonparametric estimation of survival curve with interval censored data].

Although survival analysis dealing with right-censored data has enjoyed wide use, analysis of data with left-censored and interval censored cases is available only to a very limited number of clinical researchers because of the difficulty in understanding the concepts and performing the calculations. This paper applies Turnbull's self-consistency algorithm, which he applied in his paper on survival data with only left-censored cases, for nonparametric estimation of survival curve including both left and interval censored data. A difference in the estimates of survival rate among different modes of calculation was demonstrated using the data from the Hematopoietic Cell Transplantation Registry of the Japan Society for Hematopoietic Cell Transplantation, which illustrated the necessity of a correct analysis.

Algorithms↗
PubMed1993

GeneView: multi-language human gene mapping library with a graphical user interface.

GeneView is a newly developed human gene mapping library system that works on an X-Window platform. This system is designed for researchers who routinely utilize gene mapping data in the laboratory but are unfamiliar with computer technology. GeneView offers various features, including friendly user interface, fast operation and visualization facility. Genetic loci are displayed graphically with an idiogram. This system can be operated in multiple languages. A current version supports Japanese and English, and can be easily expanded to include other languages. A prototype of GeneView is now installed on a SPARC (Sun4) workstation. Because of the X-Window platform, GeneView should be compatible with various types of workstations.

Algorithms↗
PubMed1993

Technical note: a pressure-sensitive sensor for measuring the characteristics of standing mounts of cattle.

A pressure-sensitive sensor that reacts to pressure by changing its electrical resistance was used to measure the characteristics of standing mounts of estrous cattle. While an estrous heifer fitted with a sensor on the rump was standing when mounted by a bull (i.e., during a standing mount), the sensor reacted to the addition and removal of pressure against it by the bull. The times of electric contact signals produced by these pressure changes were recorded to pinpoint the time of the mounted response and the duration of the mount. To detect the characteristics of standing mounts accurately, three types of sensors with different sensitivities and various positions on the rump of heifers were examined. When 13.5-cm sensors that operated with a pressure of 1,000 g/cm2 were fitted on the line combining the highest points of the left and right hip bones toward the tail, or 6.5 cm behind this position, on the rump of heifers (200 to 225 kg), mounts by vasectomized bulls (278 to 556 kg) were accurately recorded with the sensors more than 85% of the time. However, the correlation between the observed and automatically recorded lengths of mounting varied with combinations of the mounted and mounting animals or with locations of the sensor (r = .19 to .86). The pressure-sensitive sensor proved to be a promising device for continuously measuring the characteristics of standing mounts, especially the exact time at which a mount occurs.

Animals↗
PubMed1992

[Analysis of breakpoints on BCR gene in acute leukemia patients with Ph1 chromosome].

Eight cases with Ph1 positive acute leukemia (7 of acute lymphocytic leukemia: ALL, and one of acute myelocytic leukemia: AML) were studied molecular biologically to identify location of breakpoints on BCR gene in each patient. Six of the 8 patients (5 of ALL and 1 of AML) had rearrangements at bcr (M-BCR) region. Their locations of the breakpoint in M-BCR were similar to those of 59 chronic myelocytic leukemia patients. One of the remaining two patients had gene rearrangements at m-BCR-1 region in BCR intron 1, and the last patient did not have gene rearrangements at any site of m-BCR-1 and IgL C lambda region. Two cases had gene deletion at either 3' or 5' side of the bcr. A patient with bcr rearrangement was also analyzed by PCR method with reverse transcriptase (RT-PCR) and had simultaneous expressions of bcr3-abl and bcr2-abl chimeric mRNAs. These results indicate that Ph1 positive acute leukemia have heterogeneous characteristics in terms of the molecular biology. The molecular analysis will help for classifying the leukemic types and for elucidating the pathogenesis in Ph1 positive acute leukemia.

Acute Disease↗
PubMed1989

[A case of chemotherapy induced necrosis of primary mediastinal germ cell tumor].

A 17 year old male with mediastinal yolk sac tumor is herein reported. His chief complaint was anterior chest pain. Chest X-ray and chest CT indicated a 8 cm diameter mass in the anterior mediastinum. Laboratory analysis revealed 2,578 ng/ml for AFP and 54% for LDH I. HCG and CEA values were normal. Yolk sac tumor was cytologically suspected on needle aspiration specimen. Combined chemotherapy with CDDP, VP16, and PEP brought the AFP and LDH 1 values down to 10 ng/ml and 27%, respectively. The diameter of the mass decreased to 6 cm. The mass was removed together with the thymus and the right upper lobe of the lung. A post operative histological examination of the mass revealed total necrosis. Nine months after the initiation of the therapy, his AFP level was within normal limits. The patient is doing well.

Adolescent↗
PubMed1989

[Familial spontaneous pneumothorax in three siblings including identical twins].

Two identical twin brothers and their sister who suffered from spontaneous pneumothorax (ages at onset, 18, 22 and 20 years) were admitted to our hospital. Their symptoms and clinical courses were similar and all three were finally treated by thoracotomy. No other members of their family had any history of spontaneous pneumothorax. None of these cases presented any abnormal level of serum ACE or alpha 1-antitrypsin. In order to establish the monozygosity of the brothers more accurately, we examined restriction fragment length polymorphisms (RFLPs) which were shown as the band patterns of hypervariable minisatellite regions in human genomes. However there have been few reports of spontaneous pneumothorax in identical twins, but the onset of the disease tends to be the same as in our cases, suggesting a genetical background of spontaneous pneumothorax.

Adolescent↗
PubMed1989

[Aggressive natural killer cell leukemia/lymphoma--possible existence of a new clinical entity originating from the third lineage of lymphoid cells].

The morphologic, immunologic, genotypic, and functional properties of peripheral blood and bone marrow cells or cultured cells from two patients with a clinically aggressive non T, non B natural killer cell lymphoma/leukemia (ANKL/L) were described. The leukemic cells possessed medium to large granules in the cytoplasm, antigens against CD 38, CD 2, OKIal, and NKH-1 (N 901) monoclonal antibodies on their cell-surface, and also showed a high natural killer (NK) activity. In addition, these ANKL/L belonged to neither T-nor B-cell lineage, proved by studying clonal gene rearrangement for the T beta and T gamma receptor, and immunoglobulin. After we compared and investigated them with 9 cases of ANKL/L reported in other institutions, concerning immunophenotype, genotype and function, we reached the conclusion that the existence of ANKL/L originating from the third lineage in lymphoid cells is an obvious fact, suggesting this new clinical entity. It is important that all patients who have this type of a clinical disorder be diagnosed that there is no effective form of therapy at present.

Adult↗
PubMed1989

[Late appearance of Philadelphia chromosome with bcr gene rearrangement in an acute myelocytic leukemia patient].

A case of acute myelocytic leukemia (AML-M2) with a late appearance of Philadelphia chromosome (Ph1) is presented. Chromosome analysis revealed a normal karyotype at the time of diagnosis and for 23 months, when hematological relapse occurred, accompanied by abnormal clones, 46, XX, t(9;22) (q34;q11) (78%) and 45,XX, -16, t(9;22) (q34;q11), del (5) (q13q31) (22%). The patient died of GVHD after bone marrow transplantation. Molecular analysis confirmed bcr gene rearrangement in the cells with Ph1 chromosome. Acquisition of Ph1 chromosome during the course of hematological malignancies other than CML is extremely rare. This case is undoubtedly important for the understanding of leukemogenesis and the evolution of leukemia clones. The authors discussed possible mechanisms of Ph1 acquisition in the late stages of AML.

Adult↗
PubMed1986

[A case of early laryngeal cancer observed after surgery for lung cancer].

A 56-year-old man, a heavy cigarette smoker, had his left upper lobe resected for lung cancer. Seventeen months later, he was diagnosed as early laryngeal cancer by bronchofiberscopy. In this case, postoperative follow-up study with septum cytology was extremely effective. He underwent radiation therapy for the laryngeal cancer. Today, three and a half years later, no signs or symptoms of any cancer can be found. Cases of preceding lung cancer in multiple primary cancer patients having lung and laryngeal cancer are very rare in the literature. All of them have been heavy cigarette smokers and majority of them men.

Carcinoma, Squamous Cell↗