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H Dupont

Publications and source records attributed to H Dupont.

At least 73 records · Page 4Linked to original sources

[The role of the Scanner in traumatic cerebral pathology (author transl)].

The authors describe the tomodensitometric characteristics of various traumatic cerebral lesions: extradural haematoma, subdural haematoma, contusion. In the acute phase, traumatic lesions are characterised by the typical absorption pattern of the bloody effusion and perilesional oedema. In association with these specific densitometric signs there is naturally an alteration in normal cerebral anatomy. The course of traumatic lesions may be followed using the scanner. The signs alter with resorption of the haemorrhage and the regression of oedema, as well as with the secondary development of a focal atrophic process. The advantages of the scanner over oconventional neuroradiology are considerable, not only from a medical and technical standpoint, but also for ethical and medicolegal considerations.

Adolescent↗

[New possibilities of anatomo-clinical correlation in aphasia using cerebral tomodensitometry (author's transl)].

The authors present a method using cerebral tomodensitometry to establish anatomo-clinical correlations in aphasia. They confirm, in their broad lines, the results of previous studies. They stress the importance of the material that could be studied by this method and define the ideal conditions in which future work should be carried out. (Acta neurol. belg., 1977, 77, 351-362).

Aphasia↗

[Relative concentration of deoxyribonucleic acid in the experimental deciduoma and the blastocyst of female rats: cytophotometric study].

Polyploidy level of experimentally induced deciduomata was determined by cytophotometric measures of DNA-Feulgen, with the "Ultramikrospektrophotometer UMSP Zeiss" by scanning. The antimesometrial tissue reached 32 n, 72 H after the uterine trauma, whereas the mesometrial part did not exceed a 4 n polyploidy level. With the same technics we studied the ovarian hormone, its action upon the blastocyst cellular cycle. In delayed blastocysts, synthesis was never found. OEstradiol removed the inhibition and DNA synthesis then starts again.

Animals↗

[Cytophotometric determination of the relative amounts of deoxyribonucleic acid in the nuclei of blastocysts during normal and retarded implantation in the rat].

Cytophotometrics measures of DNA-Feulgen were realized in normal and delayed implantation blastocysts of the rat. During afternoon of the 5th day of progestation, blastocysts were of two types: those nuclei of which were in G1 gap and those nuclei of which were synthetising DNA. In delayed implantation, blastocyst nuclei were in G1 or G2 gap. Mitosis were rarely seen. After oestrogen injection DNA-synthesis started again. Cell kinetics before ovoimplantation is discussed.

Animals↗

[Experimental rat deciduoma: histoenzymology].

The modifications of enzymatics activities which involved dehydrogenases (LDH, MDH and G6PDH) alkalines phosphatases (Ph. Alc., ATP/as at Ph 7,2 and Ph 9,4) and hydrolases (Ph Ac. and beta Glu) were studied during the experimental deciduomata evolution in the Rat from the 5th to the 9th day. One the 5th day the uterus were used as control. Dehydrogenases and alkalines phosphatases activites appeared in isolated cells of sub-epithelial and middle antimesometrial stroma on the 5th day. Then, on the 6th day, they distributed themselves in strings of 8 to 10 cells. On the 7th day, they were regulary arranged in the decidual area. The growing decidual tissue was always surrounded by an hydrolysis activity.

Acid Phosphatase↗

Morphological analyses of paraspinal muscles: comparison of progressive lumbar kyphosis (camptocormia) and narrowing of lumbar canal by disc protrusions.

Progressive lumbar kyphosis (camptocormia), a rare, usually familial disease in elderly patients, is characterized by inability to immobilize the lumbar spine in relation to the pelvis. CT scan reveals selective involvement of the spinal muscles with a heterogeneous appearance and is in favour of a primary disorder of these muscles. Our aim was to define the muscular lesions and clarify their nature in this particular disorder. Biopsies of the paravertebral muscles of 14 patients with lumbar kyphosis and of 20 operated on for disc herniation or narrowed lumbar canal, were studied by light microscopy, histochemistry and electron microscopy. In both groups, type 1 fibre predominance and atrophy of type 2 fibres were observed. Ragged-red fibres with abnormal mitochondria also occurred. The differential feature was increased frequency of extensive diffuse or lobulated fibrosis in camptocormia. Other features related to pathogenesis could not be determined.

Adipose Tissue↗

[Morbi-mortality after Hartmann procedure for peritonitis complicating sigmoid diverticulitis. A retrospective analysis of 85 cases].

INTRODUCTION: Hartmann's procedure (HP) is a simple operation, which can be performed by all the surgeons. However, it remains criticized (high morbimortality, low rate of intestinal continuity restoration). The aim of this study was to analyse natural history of HP and intestinal continuity restoration for sigmoid diverticulitis, and to assess risk factors for mortality, morbidity and absence of intestinal continuity restoration. PATIENTS AND METHODS: In three centers, from 1992 to 2002, 85 patients underwent HP. A retrospective analysis was performed on mortality, early and late morbidity of HP and intestinal continuity restoration. RESULTS: 22% of patients (mean age, 68 years) presented comorbidity, 17% of them, an altered immunity, and 3 or 4 Hinchey score for 64%. ASA score was > or =3 in 49% of the cases. Mean AFC and Mannheim scores were 2 and 21 respectively. Mortality rate was 14% and in-hospital morbidity, 50%. Main complications were: cardiorespiratory (18%), wound abcess (14%) and stomal (6%). No rectal stump fistula was noted. Mean hospital stay was 19+/-13 days. Late morbidity rate was 29%, mainly due to stomal complications (12%) and small bowel obstruction (7%). Intestinal continuity restoration was done in 77% of the cases, followed by only 1 fistula. Mortality rate for intestinal continuity restoration was 0% and morbidity was 13%. Mean hospital stay was 10+/-3 days. Age >75 years, ASA score > or =3 and comorbidity were risk factors for morbidity and mortality and for absence of intestinal continuity restoration. CONCLUSIONS: HP is associated with a high morbidity and mortality rates. Intestinal continuity restoration rate was high in this series. HP is a simple operation in high-risk patients with advanced peritonitis. This study allows to precise natural history of HP. Knowledge of this history is crucial for choosing the best operation (between HP and anastomosis) for patient with peritonitis complications sigmoid diverticuitis.

Adult↗

[A new era in neuroradiology. Computerised axial transverse tomography-C.A.T.T. (Emi-Scanner) and its applications (author's transl)].

With an adequate follow-up, the authors report their experience with computerised axial transverse tomography (Emi-Scanner) after its use in 500 cases. A description of the method is followed by an account of the material used in this study. They mention the safety of C.A.T.T. and the profound change which this new technique has brought about in the chronology of neuroradiological investigations. The applications of C.A.T.T. are defined in relation to conventional neuroradiological investigations. In traumatic, degenerative, infective, neoplastic and vascular disorders, as well as epilepsy, C.A.T.T. makes possible visualisation of the lesion in the majority of cases. Having dealt with each of these indications, the authors illustrate the typical appearances seen at C.A.T.T. by significant examples. C.A.T.T. reduces the proportion of angiographic and encephalographic examinations. This tendency will become even more marked with the advent of technical development which improve the power of resolution of C.A.T.T.

Adult↗

[Preliminary validation of the French translation of anxiety sensibility index-revised (ASI-R)].

Anxiety sensitivity represents a stimulus-outcome expectancy that reflects individual differences in the propensity to experience fear in response to one's arousal-related bodily sensations. It refers to the fear of anxiety-related symptoms that are based on beliefs that such sensations have negative somatic, social or psychological consequences. Anxiety sensitivity occupies an important place in theory and research on panic and related interoceptive fear disorders. Findings from this body of research indicate that this construct may act as a specific vulnerability variable in the development of panic attacks and anxiety symptoms. However, anxiety sensitivity theory also has been applied to understanding mood disorders and chronic pain disorders. Thus, as a psychological construct, anxiety sensitivity holds specific relevance to understanding panic disorders and general relevance for expanding knowledge about negative emotional functioning in other pathologies. All the research on anxiety sensitivity has been completed with the 16-item Anxiety Sensitivity Index (ASI). The review of the literature using this instrument suggested that anxiety sensitivity has three lower-order factors that all load on a single higher-order factor. The lower-order factors represent Physical-Concerns, Mental Incapacitation Concerns, and Social Concerns, and the higher-order factor represents the global anxiety sensitivity construct (21). Taylor and Cox (22) suggested that this questionnaire was not designed on an a priori basis to measure the identified lower-order factors. The low number of items for the Social and Mental Incapacitation dimensions of the 16-item ASI often leads to relatively lower levels of reliability compared to the third dimension. To address this issue, Taylor and Cox (22) developed an expanded measure of the anxiety sensitivity construct. The 36-item Revised Anxiety Sensitivity Index (ASI-R) maintains the same format as the 16-item ASI, but expands the number of content domains assessed. The ASI-R was designed to assess 6 lower-order domains identified in previous factor analytic research using the 16-item ASI (21), including fear of cardiovascular symptoms, fear of respiratory symptoms, fear of gastrointestinal symptoms, fear of publicity observable reactions, fear of dissociative and neurological symptoms, and fear of cognitive dyscontrol. The principal components factor analysis using the ASI-R among psychiatric outpatients indicated that there were 4 lower-order factors tapping the constructs of (1) fear of respiratory symptoms, (2) fear of publicly observable anxiety reactions, (3) fear of cardiovascular symptoms, and (4) fear of cognitive dyscontrol (22). A recent study (27) provided an initial psychometric evaluation of the ASI-R in a large, diverse sample of people (n = 2,786) from 6 different countries: Canada, United States, Mexico, Spain, The Netherlands and France. The data suggested that the two-factor solution is most replicable than other solutions (2 to 6 factors). The underlying structure of the anxiety sensitivity construct was generally similar across countries, tapping fear about the negative consequences of anxiety-related physical and social-cognitive sensations. Lower-order factors were moderately to strongly correlated with one another and showed good internal consistency. This manuscript presents the French translation of the ASI-R and a preliminary validation study. This research was realized conjointly with the transcultural study previously mentioned (27). Seven hundred and one French university students (non-clinical participants) completed the questionnaire at the beginning of a class. Subjects were undergraduate students from 2 universities (psychology and classics). Table I provides age, sex and marital status. There were no differences between the two groups on sex. The two groups were not comparable on age and marital status. The psychology group was older than the other was. The psychology students were also more married. The total group (n = 701) comprises 79 men and 622 women, with a mean age of 21.29 (4.85). Table II provides the normative means and standard deviations for both groups of students. There was no difference between the two groups on the total of the questionnaire (no significant interaction between group and age). In regard to the physical concerns subscale and the social-cognitive concerns subscale, there was also no significant interaction between group and age. Assessment of the internal consistency of the ASI-R yielded an overall Cronbach alpha of 0.91 for the entire questionnaire, with an alpha of 0.88 for the fear of anxiety-related physical sensations subscale and 0.83 for the fear of anxiety-related social-cognitive sensations subscale. A series of ANOVAs between male and female groups revealed significant gender differences. As shown in table IV, women had significantly higher total score than did men. They also had significantly higher physical factor and social-cognitive factor scores than did men. This finding is consistent with research that indicates that women generally report more intense fears and men less intense fears, and that they differ in levels of overall anxiety sensitivity specifically (29). This preliminary report was the first attempt to examine the construct of anxiety sensitivity using the ASI-R in a French university students. It can serve as a reference point for future research.

Adult↗

[Tomodensitometric appearances in "medical" cerebral haemorrhages (author's transl)].

On the basis of experience of more than 5,000 cases (since 1974), the authors describe the tomodensitometric appearences of non-surgical cerebral haemorrhages, together with the correlation between values of radiodensity and histological lesions. They emphasise the chronological changes which take place in the tomodensitometric appearance of the lesions and the possibility of easy repeated studies. Such studies, in combination with observation of the clinical course, have enabled the authors to give the scanner an important place in decisions to proceed to surgery. The authors stress the superiority of the scanner over invasive techniques used to explore such patients, from both an ethical as well as a diagnostic standpoint. They consider that it will be of value in the future in experimental studies aimed at elucidating the physiopathology of these lesions.

Cerebral Hemorrhage↗