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Biomedical subjects

H Dyer

Publications and source records attributed to H Dyer.

10 recordsLinked to original sources

Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy.

Forty-five measurements of diameters of 12 human cerebral arteries were performed during 10 craniotomies under moderate changes in mean blood pressure and end tidal CO2. The mean change in blood pressure was 30 +/- 16 mm Hg (standard deviation) and that of end tidal CO2 was 14 +/- 6 mm Hg (standard deviation). These changes were induced with nitroprusside, phenylephrine, and adjustment of ventilator rate. Measurements were made through the operating microscope focused at the highest power, with meticulous attention to constant angle and distance from the artery. The mean diameter change in the large cerebral arteries (carotid, middle cerebral artery, vertebral artery) was less than 4%, but the smaller arteries (anterior cerebral artery, M2 segment of middle cerebral artery) showed diameter changes as large as 29% and 21% to end tidal CO2 and blood pressure changes, respectively. These data suggest that at the time of craniotomy, diameters of the large cerebral vessels do not significantly change during moderate variations in blood pressure and CO2, but that larger changes may occur in smaller vessels. This constancy of diameter suggests that the transcranial Doppler velocities obtained during intraoperative monitoring of craniotomies may closely reflect blood flow through the insonated artery.

Aneurysm, Ruptured↗

The effects of CD-ROM on library services.

This paper presents a wide-ranging overview of compact disc technology in the library environment. It raises important issues currently being debated in the literature and aims to question and stimulate thought on the nature and purpose of CD-ROM provision in health-care libraries.

CD-ROM↗

Microbiology of chronic otitis media with effusion among Australian Aboriginal children: role of Chlamydia trachomatis.

Serum, eye secretions, post-nasal swabs, external ear swabs and middle ear effusions (MEE) were collected from 131 Australian Aboriginal children with chronic otitis media with effusion (COME). The children were all resident in a trachoma endemic region. Chlamydia trachomatis was recovered from the MEE of 2 children. Probable bacterial pathogens were isolated from 34 (12.7%) ears. The remainder were sterile (52.4%) or contained normal skin flora (34.9%). Serum and secretions were examined by the microimmunofluorescent technique for the presence, titre and serotype of anti-chlamydial antibody. Antibody, predominantly of the C serotype, was found in a high percentage of sera (80%) and secretions (approximately 50%). This serotype is associated with ocular trachoma. It is concluded that C. trachomatis is associated with COME among some Aboriginal children in this trachoma endemic area.

Adolescent↗

Chronic ear disease in Australian Aborigines.

Ear, nose and throat diseases in children living in the Kimberley region of Western Australia have been systematically studied over the last 15 years. A "diagnostic triad" is described; this offers a comprehensive approach to the assessment of middle-ear disease. The aetiology of chronic ear disease in Aboriginal children has been investigated. Management problems of deafness are discussed.

Adolescent↗

The response to acupuncture therapy in patients with chronic disabling pain.

Twenty-one patients had acupuncture treatment for chronic, disabling pain. Ten (47.5%) thought they had obtained worthwhile relief by the time treatment was completed. Six (30%) had no or negligible benefit and five (25%) had some aggravation of their pain at some stage of the procedure. In this group of patients, with the technique we describe, we were unable to achieve the high degree of short-term success claimed by other workers. Until further scientific studies can confirm the value of acupuncture in medical practice, we urge caution in the use of this procedure.

Acupuncture Therapy↗