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H E Bowman

Publications and source records attributed to H E Bowman.

17 recordsLinked to original sources
PubMed1997

Updated protocol for the examination of specimens removed from patients with colorectal carcinoma. A basis for checklists.

The Cancer Committee of the College of American Pathologists has updated and expanded their protocol for the pathologic examination and reporting of specimens from patients with colorectal carcinoma, which was originally developed in 1989. The updated protocol incorporates all basic pathology data of diagnostic and prognostic significance appropriate for the treatment of patients with colorectal carcinoma. The purpose of the protocol is to serve as a basis for the development of checklists, as an outline for full narrative reporting, as a basis for research protocols, or as a guide for other types of synoptic or reporting formats. The protocol is stratified to accommodate the surgical procedures usually employed for colorectal carcinomas, including incisional endoscopic biopsy, polypectomy, local excision (transanal disc excision), and colon/colorectal resection (eg, segmental resection, total colectomy, abdominoperoneal resection). Explanatory notes detailing specific procedures and rationales for documentation of specific pathologic data are included in the protocol. The protocol uses the recently revised TNM staging system for colorectal carcinoma defined by the American Joint Committee on Cancer and the International Union Against Cancer.

Adenocarcinoma↗
PubMed1980

Reproducibility of syphilis serology results.

In order to evaluate the stability and reproducibility of syphilis serology qualitative results, the results reported on replicate specimens in the College of American Pathologists Quality Evaluation Program during 1978 were examined. There is evidence of good stability of syphilis serology specimens and reproducibility of qualitative results separated in time by as much as nine months for specimens that are nonreactive or highly reactive. However, there is evidence of lack of such stability and reproducibility of weakly reactive specimens. There is no striking difference in these results for the RPR card or VDRL test. The FTA-ABS test is more stable over time. There is some indication that the lack of stability and reproducibility of weakly reactive specimens is primarily a function of the stability of the specimen, with laboratory performance playing a secondary role.

Pathology, Clinical↗
PubMed1979

Infectious mononucleosis test performance on CAP survey specimens.

The participant performances on 1977 and 1978 infectious mononucleosis survey specimens are tabulated. The various methods utilized gave similar results on negative specimens. Commercial reagent kits incorporating differential absorption performed somewhat better on positive specimens than kits without differential absorption. Many of the commercial reagent kits performed very poorly on the false postitive specimen.

Antibodies, Viral↗
PubMed1977

Lymphocyte blastogenic responses to allogeneic leukocytes and autochthonous tumor cells in colorectal carcinoma.

The blastogenic reactivity of peripheral blood lymphocytes (PBL) and mesenteric lymph node lymphocytes (LNL) against normal allogeneic leukocytes and autochthonous colorectal carcinoma cells is evaluated in 36 patients, and correlated with the patient's Dukes classification. Mesenteric LNL react significantly better than PBL to allogeneic leukocytes in both Dukes B and C (p less than 0.05). There are too few patients in Dukes A and D to permit statistical evaluation but the trend is the same. By contrast, LNL fail to react to autochthonous tumor cells in all classes, except in a few Dukes B patients. The proportion of PBL reactivity to autochthonous tumor cells seems to increase for Dukes C and D. It is possible that specific lymphocyte reactivity in colorectal carcinoma may be related to the antigenicity and immunogenicity of the tumor.

Antigens, Neoplasm↗
PubMedDate not supplied

Solitary adenomas in juvenile patients.

Ten patients under 20 years of age who had solitary adenomas of the colon or rectum, selected for study from case records of the period 1959--1979, have been followed for 1--20 years (average, 10 years). Though no malignancies have been identified so far, this series points out that adenomas do exist in pediatric patients. Hence, one should not assume that every polyp in patients under the age of 20 is automatically a juvenile polyp and, therefore, benign. Any patient with a solitary adenoma, or who has multiple polyps, whether adenomas or juvenile polyps, should be followed at appropriate intervals with sigmoidoscopy, x-ray, and, possibly, colonoscopy.

Adolescent↗