Comparison of DDE and PCB residues in the general diet and in human blood--Ontario 1986-87.
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Biomedical subjects
Publications and source records attributed to H E Braun.
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This study examines the influence of buffering capacity of the soil on the levels of cadmium in the kidney, liver and muscle of moose and white-tailed deer from nine sampling sites (four buffered and five non-buffered) in Ontario, Canada. Tissues collected from hunter-killed moose and deer during 1984 and 1985 were analysed for cadmium. Tissue from moose in the non-buffered Algonquin Park site (21.9 +/- 1.1 mg/kg wet weight) and the buffered St. Joseph Island site (12.7 +/- 3.2 mg kg-1) had the highest mean levels of kidney cadmium compared with other sites sampled in Ontario. The highest mean levels of kidney cadmium in deer were found in the non-buffered Loring site (15.1 +/- 0.8 mg kg-1) adjacent to Algonquin. From all sites, the level of cadmium was highest in kidney, lower in liver and was often undetectable in muscle. Cadmium level increased with animal age (p less than 0.05). Levels of cadmium in Ontario moose from some regions are comparable to those found in Quebec and Manitoba and are considerably higher than those of Maine and Scandinavia. Levels of cadmium in kidneys and livers of white-tailed deer in parts of Ontario are considerably lower than those in Pennsylvania. As a result of this study, the Ontario Ministry of Natural Resources, in consultation with the Ontario Ministry of Health, has recommended that the public not consume kidneys or livers of Ontario moose and deer.
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Between 1976 and 1978, 248 harp seals were sampled from 5 locations in the Northwest Atlantic and Arctic for organochlorine (OC) residue analysis in tissue. Blood, kidney, brain, muscle and blubber samples were analysed for PCB, DDT, dieldrin, hexachlorobenzene (HCB), and heptachlor epoxide. Levels were generally greatest in blubber tissue. Overall, mean levels of DDT and PCB were greater than those of other OC. A barrier prevented OC compounds from accumulating in the brain to the level one might expect in lipid tissues. Positive correlations were found between 1: DDT and PCB, 2: DDT and dieldrin, and 3: PCB and deildrin. Male harp seals bioaccumulated DDT, PCB, heptachlor epoxide and dieldrin with age. As a group, adult males sampled in the Gulf of St. Lawrence carried the highest concentrations of all OC, except that chlordane did not appear to bioaccumulate and levels of hexachlorobenzene were minimal. Females generally ceased exhibiting significant bioaccumulation once breeding age was reached, due to transplacental and transmammary residue transfer of OC from mother to pup. There were some significant differences in OC levels between locations with DDT: Gulf greater than Front; PCB: Gulf greater than Front; dieldrin: Gulf greater than Front; heptachlor epoxide: Front greater than Gulf. No significant differences were found, however, when northern locations (Grise Fiord, Northwest Greenland, Pangnirtung) were compared to southern (Gulf, Front) on a group basis. The latter is not surprising in view of the harp seals extensive cyclical annual migration between the southern breeding grounds and the High Arctic.
Between 1976 and 1978, 249 harp seals were sampled from five locations in the Northwest Atlantic and Arctic for heavy metal and selenium residue analyses in tissue. Significant loading was apparent only in blood, brain, kidney, liver and muscle. Samples were analysed for mercury (Hg), selenium (Se), copper (Cu), cadmium (Cd) and lead (Pb). The seals carried higher levels of Cd than of the other metals. Residue levels of Cd were highest in kidney tissue; levels of other metals were highest in liver. Both males and females bioaccumulated Cd, Hg and Se. Cd, Hg, Se and Cu residues were detected in tissue from neonatal seals, indicating that transplacental and transmammary transfer of these elements had occurred. Despite the passage of residues from mother to pup, females bore significantly higher levels of Hg and Cd than males. Conversely, levels of Cu, Se or Pb did not appear to differ significantly between sexes. There was considerable individual variation in residue levels. This, coupled with the extensive annual migration undergone by these animals, made it difficult to arrive at definite conclusions regarding geographic accumulation patterns.
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