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Biomedical subjects

H E Kaeser

Publications and source records attributed to H E Kaeser.

At least 19 recordsLinked to original sources

[Polyneuropathies with an abnormal tendency for pressure-induced paralysis].

A 52-year old man is discussed. At age of 14 he was noticed to have pes cavus and thin shanks on both sides und drop foot on the right side. Since that time he has been suffering from episodic sensory loss in the distribution of the ulnar, median, peroneal and trigeminal nerves. An extended sensory loss around the pelvis and the posterior aspect of the thighs was a rather unique feature in this patient. As the patient refused nerve biopsy it cannot be decided whether peroneal muscular atrophy with multiple nerve compressions or if the entity of polyneuropathy with liability to pressure palsies was present.

Diagnosis, Differential

[Rare form of uveitis with neurological symptoms: the Vogt-Koyanagi-Harada uveomeningoencephalitic syndrome].

A 51-year-old Italian woman developed migraine-like headaches with increasing frequency 5 years after menopause. The simultaneous onset of severe bilateral uveitis, neurological signs such as vertigo, hearing loss, small sensomotor hemisyndrome, cognitive brain dysfunction and lymphocyte liquor pleocytosis confirmed the diagnosis of Vogt-Koyanagi-Harada syndrome, a rare disease of probably autoimmune origin with destruction of pigment containing neuroepithelium. Other vasculitic diseases, especially those of infectious or rheumatologic origin, were excluded. Systemic corticoid treatment suppressed the activity of the illness but on dose reduction relapses occurred. Additional immunosuppressive medication prevented uveitic relapses and made it possible to reduce the corticoid dose.

Cyclophosphamide