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Biomedical subjects

H E Vitzthum

Publications and source records attributed to H E Vitzthum.

16 recordsLinked to original sources

[Innervation anomalies--mechanism of adaptation or embryonal malformation?].

After injuries innervationanomalies are observest. Are these anomalies mechanismen of adaption or an embryological malformation, is a still mansverst question. This paper tries some contributions to the answer. The use of modern muscleenzymhistochemistry in connection of histological findings of nerves in certain levels gives assertions on anomalies of innervation and mechanisms of reinnervation. After 14, 28, 56 and 112 days tissues of nerves and muscle from 66 female WISTAR-rats were investigated after various lesions. We have found in 15 not operated rats that the so called typegrouping can be a expression of reparation process after microlesions of nerve and muscle. We interpreted the anomalies as an expression of a reaction of adaption. The innervationanomalies succeeded in the fore and behind extremities of the rate indirectly. Above all embryological malformations can explain some anomalies of innervation on the fore extremities. We conclude from our results that communication among nerves and nerve bundles were developed or activated. These mechanism seems to be effective only about a short distance. We did not find a MARTIN-GRUBER-anostomosis. The findings of reinnervation of the musculature were attributed to cross-innervation, collateral and orthotope reinnervation. Generally the innervationanomalies are an expression of plasticity of the peripheral nervous system in all periods of life. In the first place we interpreted this phenomenous as adaption of nerves after injury and in the second place as embryological malformation.

Animals

[Nerve fiber regeneration in preformed tissue spaces].

Described in this paper is a new artificial chamber model to enable in vivo investigation of nerve fiber regeneration. Transection of the sciatic nerve of a rat was followed by analysis of axonal regeneration and revascularisation in the tissue chamber. Vascularisation of the endoneurium via the newly formed epineurium and perineurium was almost physiological in the cavity formed. The latter was found to be suitable for application of drugs and neurotrophic substances.

Animals

[The morphology of the lumbar spinal canal].

Measurements of cast preparations of epidural cavities yielded data characterising the "internal silhouette" of the lumbar vertebral canal. Three groups of different shapes of lumbar vertebral canal were found to be statistically distinguishable from each other. These are determined by the constitution of the patient. The different spatial capacity of the three types and the different relations of the diameters modify the value of the isolated determined distance, for example of the sagittal diameter at L5, which is a clinically extremely relevant factor that must be taken into account.

Dura Mater

[Assessing the myelogram of the narrow spinal canal].

The myelograms of 40 patients who had been operated on because of stenosis of the lumbar vertebral canal, were retrospectively assessed and measured. As was to be expected, the diameters were reduced, especially the sagittal diameter. Three configurations of the epidural space were seen representing different spatial capacities. The type occurring particularly often in lumbar osteogenic stenosis, which is conditioned by the patient's constitution, must be considered as a predisposing factor for the manifestation of a lumbar compression syndrome on account of its small capacity.

Female

[Innervation anomalies].

The deviation from anatomically described innervation can often occur. It is mainly described on muscles of the limbs. Constant attention should give to this fact during the process of diagnosis of peripheral nerve lesions. Electrophysiological methods (EMG, ENG with blockade of nerve, collision technique and simultaneous lead) can help to detect this anomalies. Double innervation, abnormal innervation and communications among nerves are causes of anomalies of innervation. The fact of communications of fibers among nerves is better called "nerve communication" than "nerve anastomosis". It is vague whether this anomalies of innervation are embryological malformations or reactions of adaptation after different diseases.

Arm

[Primary melanoblastoma as a cause of occlusive hydrocephalus].

Primary melanoblastomas of the Central Nervous System are comparatively rare tumors. Lumpy or diffuse forms may occur either alone or in combination. On the basis of actual case histories, diffuse cerebral and medullary melanoblastoma is presented as a rare cause of occlusive hydrocephalus.

Brain

[Injuries of the basilar artery].

In 2 to 3 per cent of the severe craniocerebral occlusions of the cerebral basic arteries are observed. Traumatic vertebralis and basilaris thromboses are very rare. In view of the modern procedure in diagnostics and therapy the prognosis of these life-threatening traumatic consequences are not infaust. According to a casuistic information pathophysiology, diagnostic procedure and therapeutical possibilities, microsurgical or by local fibrinolysis, are discussed.

Adult

[Late results following treatment of peripheral nerve injuries of the upper extremity].

The authors re-examine cases of complete peripheral nerve injury of the upper extremity. Motor activity and sensibility assessment make use of Highet's scale. Some general principles of surgical treatment of peripheral nerve injuries are presented and individual factors which influence its results are worked out, e.g. moment of diagnosis, kind of nerve suture, moment of operation, age of patient, grade of injury, concomitant injuries, and length of graft. Conclusions are drawn for the concept of treatment.

Adolescent

[Non-Hodgkin lymphoma (NHL) as a primary finding in the central nervous system].

The clinical picture is dealt with on the basis of seven cases of primarily recognised non-Hodgkin's lymphomas in the CNS treated by us. Because of the frequently serious initial situation immediate surgical intervention can on the one hand improve or remove the paralysis and, on the other, it will lead to histological diagnosis. Elderly patients with a lower degree of malignity show a better prognosis.

Humans

[Delayed encephalopathy].

A specific clinical course of light covered craniocerebral traumas patients, corresponding to 2 per cent of all clinically treated craniocerebral traumata. Twilight states and transient neurological and ophthalmological symptoms characterise the clinical picture. The prompt reversibility of the symptoms indicates a functional damage requiring a differential-diagnostic consideration of morphological sequelae of traumas, for which instrumental diagnostics and, if required, surgical consequences are necessary.

Accidental Falls