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Biomedical subjects

H E Webb

Publications and source records attributed to H E Webb.

At least 73 records · Page 4Linked to original sources
PubMed1975

A new method for monitoring subclinical virus infections of the central nervous system in mice.

The course of a subclinical virus infection of the central nervous system (CNS) of mice has been followed by measuring spontaneous motor activity using Animex equipment. A significant drop in activity occurred on the 5th and 6th day after inoculation with the A774 (avirulent) strain of Semliki Forest virus (SFV) before histological changes were apparent but at the same time as maximum brain virus titre. The relationship of the fall in activity to changes in the pattern of weight gain, food and water intake was also investigated.

Adenoviridae Infections↗
PubMed1970

Antilymphocyte serum and tissue culture used to investigate role of cell-mediated response in viral encephalitis in mice.

Antilymphocyte serum given to suppress selectively the cell response to Langat virus in Swiss albino mice prolonged the average survival times. In vitro, lymph-node cells from virus-immunized mice were strongly cytotoxic for syngenic non-neuronal brain cells infected with virus. The implications of these findings are discussed, with particular reference to the concept of autoimmunity.

Animals↗