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Biomedical subjects

H Eschapasse

Publications and source records attributed to H Eschapasse.

At least 19 recordsLinked to original sources

[Surgical treatment of bronchial cancer--current status].

It is still difficult to codify the surgical treatment of primary bronchogenic cancer. In spite of improvements of means of diagnosis and of detection of metastases the results at intermediate and long term are frequently modest. The techniques of resection are improved, and this is the method of choice in all cases where function and anatomical situation are permissive. The risk of the operation is minimal if the respiratory function is well, even with very extended resections. This is the greatest progress during the last 30 years. Surgery can cure only tumors which are still localized. Research on complementary treatment of extended forms is still necessary.

Carcinoma, Bronchogenic↗

[Mediastinitis caused by odontogenic anaerobic bacteria].

Anaerobic odontogenic mediastinitis appeared to be on the increase. The case described had a favourable outcome. The aetiology and pathology of this disease, the dreadful prognosis of which was a mortality rate of 50%, were discussed. The aggravating factors appeared to be general, these patients presenting a particular predisposition, due to steroids and malnutrition, and anatomical, as the cellulitis spread along cervical fascial planes. The treatment always required was mediastinal surgical drainage by a transcervical approach or by thoracotomy, the association of three antibiotics (a penicillin with an imidazole, an aminoglycoside or a macrolide) and a high energy and nitrogen intake.

Adult↗

Surgery for cardiac complications caused by endocardial mural fibrin deposits in a hypereosinophilic syndrome.

A 31-year-old man presented with rapid onset of intractable congestive heart failure during the course of chemotherapy for eosinophilic leukemia. Patients with a hypereosinophilic syndrome usually die from complications of eosinophilic infiltration and fibrosis in target organs. The resulting cardiac lesions are a cause of death among these patients. Surgical intervention enabled our patient to survive the immediate medical crisis and has prolonged his life.

Adult↗

Repair of large chest wall defects: experience with 23 patients.

The repair of large chest wall defects has been done on 23 patients who had 28 operations. Twenty-two patients had a neoplasm of the thoracic cage, while 1 had a large inflammatory mass. Nine patients had a partial lung and 3 a partial diaphragmatic resection done en bloc with the ribs. Seven resections were on the sternum. The repair was made either with a soft prosthesis (nylon mesh in 3 and Marlex mesh in 12 operations) or with a composite prosthesis of methyl methacrylate and metallic or Marlex mesh (13 operations). The association of methyl methacrylate and Marlex combines the solidity and the easy shaping of methyl methacrylate with the advantages of the mesh for an easy fixation and excellent incorporation. When the skin and the muscles are resected with the osteocartilaginous wall, an omentum flap is placed between the skin and the prosthesis to facilitate healing. There was one postoperative wound infection, which cleared with appropriate antibiotics. No prosthesis has extruded. The cosmetic and functional results are satisfactory. Repair of very large chest wall defects after resection can be done safely.

Adolescent↗

[Interest of pleurectomy as a complement of emphysematous bullae resections (author's transl)].

Complementary pleurectomy following emphysematous bullae resection is justified only if it improves long-term results in comparison with surgical symphysis obtained by pleural irritation. This cannot be proved at this time. On the other hand, in spite of their limitations, experiments in man suggest that this pleurectomy does not cause any particular complications. In the animal, this parietal pleural resection causes cortical fibrous alveolitis which is not present after other symphysis processes. The authors suggest therefore the use of pleurectomy as a complement of bullae resections in acute and diffuse emphysema.

Acute Disease↗

[Prevention of thrombo-embolic accidents after pneumonectomy (author's transl)].

The authors analyzed the progress in the prevention of thrombo-embolic risk in 550 pneumonectomies divided chronologically in 4 groups : without anticoagulant treatment, with post-operative anti-vitamin K, with post-operative calcium heparinate, with pre and post-operative calcium heparinate. This study revealed the necessity of a pre-operative systematic preventive treatment : systematic, as there is no biological reason enabling the prevention of thrombosis risk. Pre-operative, because venous thrombosis and pulmonary embolism can occur very early.

Heparin↗

[Dystrophic hyperlucent lung (author's transl)].

Emphysematous bullae isolated on a healthy lung and primitive progressive dystrophic emphysema all belong to the dystrophic hyperlucent lung and are surgical cases. Having recalled the excellent prognosis of isolated bullae, the authors analyzed the surgical indications in the progressive dystrophic emphysema concerning 66 observations of which 52 cases were operated. They showed that surgery provided many improvements and that making a pleural adhesion during the intervention limited the bullous evolution of the disease. Results plead in favour of early interventions and wider indications.

Adult↗

[Funnel chest. Generalities, Surgical treament].

The Pectus excavatum (P.E.) or funnel shaped thorax is a relatively frequent malformation of the chest wall. After a survey of references, the authors recall the main elements of an affection with functional results sometimes important. The results of surgical treatment are analized in relation with the kind of intervention and the age of the patients. Modelling sternochondroplasty with temporary retrosternal support for the deep funnels, the subcutaneous filling of the deformity in slight P.E. should at present be recommended. Definitive results can only be appreciated after 3 to 5 years.

Adolescent↗

Pulmonary surfactant and dog lung transplant.

The pulmonary sufactant was studied in the dog after crossed lobe autotransplantation and the influence of graft preservation time before reimplantation was considered. 1) The phospholipid composition of the grafted lobe is unchanged. 2) The incorporation of 32P orthophosphate in phosphatidylcholines is increased in the entire grafted lung (transplanted and ungrafted lobes). 3) Conservation of the graft for 48 hrs before the autograft changes neither surfactant composition nor 32P incorporation.

Animals↗