[Hematopoietic foci as a cause of cystoid mandibular lesions].
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Biomedical subjects
Publications and source records attributed to H F Sailer.
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Of 65 adult class III patients with retropositioned maxillae subjected to Le Fort I Osteotomy, 16 were selected at random for a clinical and cephalometric examination of postoperative stability. Lateral head plates prior to treatment, 6 weeks post-treatment and 1 year post-treatment were compared. In 9 out of the 16 cases 5 year post-treatment head plates were available. Statistical evaluation of the longitudinal differences revealed the repositioned maxilla to remain stable. The upper lip, however, lost 44% of its postoperative advanced position within the 1st year subsequent to the operation. In the period between 1 year and 5 years postoperatively no further cephalometric changes of any significance were recorded.
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Subperiosteal resection of the entire ramus including the condyle followed by immediate reconstruction using a similar allogenic lyophilized mandibular segment was performed in 5 adult monkeys (Macaca irus). One further animal served as a control for the operative technique and another provided the initial 2 rami for implantation into the first of the 5 experimental animals, while an additional animal was used to supply fresh bone specimens for immunological studies. Sequential polychrome labelling with oxytetracycline, DCAF and haematoporphyrin was used, and X-rays were taken at regular intervals; the reconstructed condyles proved to be radiographically and macroscopically indistinguishable from those of the control side. All reconstructed bone transplants took. Immunological investigations (leukocyte-migration-inhibition tests) revealed that lyophilized allogenic bone grafts exhibit reduced antigenicity.
The clinical and radiological progress covering a period of 11 months is reported in a patient in whom a resected segment of the mandible was immediately replaced by an allogenic, lyophilized mandibular segment previously taken from a cadaver.
A case of eosinophilic granuloma of the mandibular condyle in a 38-year-old woman is reported. Clinically, the lesion presented as a malignant process with pathological fracture. The problems related to radiographic and histological diagnosis are discussed.
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