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Biomedical subjects

H F Zeilhofer

Publications and source records attributed to H F Zeilhofer.

33 records · Page 2Linked to original sources

[Computer-assisted documentation of mandibular fractures].

For the registration, documentation and evaluation of patient data in cranio-maxillo-facial (cmf) trauma surgery a Windows-based application front end for relational data base systems (RDBS) has been developed. A simple-to-learn, easily reconfigurable user interface can be adjusted to the dynamically changing needs of individual departments. A graphical user interface (GUI) eases the entry of complex information like fracture positions, the location of implanted osteosynthesis material, etc. The new program also simplifies the daily routine documentation tasks. Being linked to a Hospital Information System (HIS) it makes use of the patients' individual base data stored there. Statistical data for various studies can be extracted from the database. The program has been successfully tested on a collective of 1.178 cmf trauma patients. Predefined analyses can be generated now by the simple click of a button for various case selections. New users learn to operate the program in a very short time.

Computer Graphics↗

[Neurologic examinations for facial nerve damage in surgically treated mandibular collum fractures].

Transcranial magnetic stimulation is a new method for objective evaluation of the facial nerve without constraints for the patient. By the first time, especially cortical lesions can be detected objectively. Using this method, a permanent disturbance of the ramus marginalis mandibularis after operative treatment of fractures of the mandibular condyle could be certainly excluded. Therefore, because of the clear presentation and the possibility of enlargement, the deep submandibular approach, using a correct operative technique, can be strictly recommended.

Electromagnetic Fields↗

[Equipment and transducer-independent 3D ultrasound in the maxillofacial area].

AIM: The use of a new 3D ultrasound system should reduce the drawbacks of former 3D workstations (long image generation time, limited use due to the need for special 3D transducers), so that it is now applicable in daily clinical routine. METHOD: An ultrasound 3D workstation was used based on a pentium PC platform, employing a magnetoelectronic position detection system for spatial reconstruction of conventional 2D B-scan image sequences. RESULTS: Better assessment of topographico-anatomical spatial relationships was achieved when presenting pathological findings, especially in assessing lymph nodes and salivary stones. Pathological processes in the maxillofacial area occurring during a period of five months were visualised. CONCLUSION: The method of 3D reconstruction of standard two-dimensional electronic scans, as presented here, is the first method of its kind enabling applicability in daily clinical routine thanks to rapid imaging. The images can be produced with any ultrasound unit or transducer. First clinical results in maxillofacial surgery clearly show improved diagnostic possibilities although there still room for an improvement of the image quality. The possibility of semi-automatic exact volumetry appears meaningful especially in the investigation of lymph nodes. Integration of colour duplex sonography will further enhance the diagnostic value of this method.

Humans↗

[New possibilities in computer-assisted image processing for ultrasound diagnosis in mouth-jaw-facial surgery].

The use of a digital image processing system in ultrasound diagnostics offers not only the advantage of a space-saving archiving without loss of quality, but also a clearly higher efficacy of the examination is achieved. An interactive of system findings leads to a more complete examination and evaluation, thus increasing the reliability and the objectivity of the examination. The standardized findings by use of text components mean at the same time a clear saving of time. Moreover, this system is very comfortable not only for the comparison of different images, but also for the scientific evaluation and processing of the image data. By digitalizing the sonographic images the visual data can be processed in a personal computer. Thereby, for maxillofacial surgery a simple and fast dynamic-functional evaluation of the temporomandibular joint was made possible. By archiving without loss of quality and by higher reliability, objectivity and efficacy of the sonographic examination important preconditions for quality care in ultrasound diagnostics have been achieved.

Head and Neck Neoplasms↗

[High-frequency videocinematograpphy for the objective imaging of the velopharyngeal closure mechanism in cleft palate patients].

The use of high-frequency video cineradiography makes possible an objective and dynamic rendering of the individual velopharyngeal closer pattern. The high resolution and the depiction of the finest mucosal structures while in motion achieved by this technique opens up the possibility of exact and objective 3-dimensional evaluation of the velopharyngeal gap. Following secondary velopharyngoplasty on 80 cleft palate patients, the velopharyngeal closure was studied by means of high-frequency video cineradiography and this rendering was then compared to results obtained by nasoendoscopy and to the clinical findings. It became definitely apparent that the radiological technique is markedly superior in relation to clearness of depiction and ease of use, especially in young children. This imaging technique can be recommended without reservation for pre- and postoperative control of speech-improving procedures.

Adolescent↗

Rapid protyping technology in medicine--basics and applications.

Using medical models built with Rapid Prototyping (RP) technologies represents a new approach for surgical planning and simulation. These techniques allow one to reproduce anatomical objects as 3D physical models, which give the surgeon a realistic impression of complex structures before a surgical intervention. The shift from the visual to the visual-tactile representation of anatomical objects introduces a new kind of interaction called 'touch to comprehend'. As can be seen, from the presented case studies of maxillo-cranio-facial surgery, the RP models are very well suited for use in the diagnosis and the precise preoperative simulation of skeleton modifying interventions.

Acrocephalosyndactylia↗

[Numerical simulation (FEM) of the human mandible: validation of the function of the masticatory muscles].

The article describes part of a research project aiming to develop a new modular software tool for the individual dynamic numerical simulation of the human mandible using the finite element method (FEM). Its planned use in the clinical setting makes it very important to validate the results of the simulations. Here, the function of the masticatory muscles is to be tested. On the basis of biomechanical data from the literature, standard movements, such as closing the mouth, forward movement, lateral movement or backward movement, were dynamically simulated. Apart from muscle activity, the movements of the mandible are defined by the temporomandibular joint. At present, translating the condylar dynamics to the simulation still poses problems. For this reason, therefore, simulations of the two extreme cases "fixed" and "force-free" condyles are compared. While in the case of fixed condyles, some of the movements could be reproduced either not at all or only weakly, in the case of force-free condyles, all standard movements were reproduced qualitatively, albeit without the guiding effect of the joint capsule or the articular disc.

Biomechanical Phenomena↗

[Urokinase-type plasminogen activator (uPA) and its inhibitor--new prognostic factors in oral squamous cell carcinoma].

Several cell biological studies have shown that the invasiveness of different malignant tumors (breast, renal, prostate, gastric, ovarian cancers) depends at least in part on the urokinase type plasminogen activator (uPA) and its inhibitor PAI1. uPA converts plasminogen into plasmin. Plasmin degrades tumor matrix components and starts invasion and metastasis. Our target was to see the possible prognostic relevance of the tumor-associated proteolytic factors and to compare with tumor size, nodal status and grading. Our results suggest that the invasive and metastatic potential of squamous cell carcinoma is correlated with overexpression of uPA and PAI1.

Algorithms↗