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Biomedical subjects

H Fahrenkrug

Publications and source records attributed to H Fahrenkrug.

7 recordsLinked to original sources
PubMed1994

Drinking patterns, risk taking and road accidents of young drivers: results of a Swiss case-control study.

A case-control study was conducted to test hypotheses about involvement in alcohol-related road accidents. Cases were defined as all male drivers between 18 and 25 years of age who were involved in a police-registered alcohol-related road accident in the Swiss cantons of Vaud and Ticino or the city of Zurich in 1990 and who had a BAC level of 0.8% and more (N = 306). Accident-free controls were drawn from registers of all persons with a driver's licence, matched for sex, age, and place of residence (N = 612). The main research instrument was a questionnaire distributed to cases and controls. Since response rates were relatively low in both groups (ca. 35%), specific analyses were undertaken to exclude the possibility of a selection bias. Results demonstrated that drinking pattern and risk behaviour were important contributing factors to the accidents. Especially, male persons with a permanent heavy-drinking style, males with a risky-driving style plus a regular or periodically heavy-drinking style, and persons who enjoy taking risks and drink to cope, increase their risk of being involved in an alcohol-related traffic accident more than sixfold. A tendency to engage generally in risky behaviour did not increase the risk of involvement in an alcohol accident.

Accidents, Traffic↗
PubMed1993

[Addiction problems in the occupational environment].

The article discusses the context of a topic currently very much under discussion in Switzerland. It provides reflections on the concept of "addiction"--better replaced by "dependence syndrome"--and summarizes the few research results concerning the Swiss situation. Due to the lack of basic epidemiological data the prevalence of "dependence-related" problems at the work place and the actual consequences and costs of substance abuse can only be estimated. In a society with rapidly changing working conditions and requirements the common stereotypes of "alcohol-prone" occupations need a critical revision. Theoretical hypotheses are most advanced in the area of substance abuse in relationship to work-related stress coping.

Adaptation, Psychological↗
PubMed1993

Alcohol and accidents in Switzerland--a critical review.

The analysis of alcohol-related traffic accidents points to a negative relationship between the average amount of alcohol consumed and the percentage of alcohol-related accidents. The data show that the officially registered problem-rates among drivers under the influence of alcohol depend primarily neither on consumption trends nor on general preventive factors, but, rather on the capacity for accident detection, the recording practices of the authorities and a less tolerant public opinion. Regional differences in the willingness to enforce control measures are related to varying cultural drinking contexts. The under-reporting of occupational accidents reflects an undue emphasis in insurance statistics which are based on a guilt/moral concept which is used to justify sanctions, such as cuts in insurance benefits. It is clear from the empirical evidence, that the broad press coverage on 'alcohol-related' ski accidents proves to be a typical case of problem amplification.

Accidents↗
PubMed1988

[Schoenlein-Henoch purpura in Borrelia burgdorferi infection].

In a 24-year-old patient suffering from recurrent purpura Schoenlein-Henoch, there were found positive Lyme-spirochete IFT. Due to the motion of titres in immune fluorescence examinations the purpura seems to be likely one form of a late manifestation in borrelia infection.

Adult↗
PubMed1981

[Stimulation of hematopoietic stem cells with serum specimens of patients with polycythemia vera].

Mononuclear cells from the peripheral blood of normals and patients with terminal renal insufficiency on hemodialysis were set up in methylcellulose cultures with and without addition of sera of patients with polycythemia vera (pv). In renal patients we found more intensive stimulation of hematopoietic progenitor cells after addition of pv-sera than in normals. The findings suggest a hematopoietic factor in sera of pv which is not identical with erythropoietin.

Cells, Cultured↗
PubMed1981

[Long-term cultures in polycythaemia vera as proof for dependence on erythropoietin (author's transl)].

In eight patients suffering from polycythaemia vera, the proliferation of erythroid colonies in methylcellulose with and without exogenous erythropoietin was studied. After three and five weeks, respectively, no colonies grew. Due to addition of erythropoietin more erythroid colonies proliferated which could be cultivated over nine weeks. The experiments suggest that the erythropoiesis in polycythaemia vera depends on erythropoietin.

Adult↗