PubMed Health⌕ Search

Biomedical subjects

H Frohmüller

Publications and source records attributed to H Frohmüller.

At least 37 records · Page 2Linked to original sources
PubMed1993

[Treatment of ureteral calculi in bone coverage using in situ ESWL in prone position].

From January 1988 to February 1992, a total of 26 patients with calculi in the middle third of the ureter underwent primary in situ ESWL in the prone position. All treatments were performed in sedoanalgesia using the Dornier HM 3 lithotriptor. During and after ESWL in the prone position, severe complications did not occur. Of the 26 patients, 10 (38%) were treated by a single application of ESWL. No auxiliary measures were necessary, and they became stone-free within 3 months following treatment. In another 9 patients (35%) auxiliary measures were required for visualization of radiolucent calculi or to relieve a urinary tract obstruction with incipient septicemia. All these auxiliary measures could be performed in sedoanalgesia. In the remaining 7 patients (27%), in whom stone disintegration following ESWL was incomplete, ureteroscopic lithotripsy techniques had to be applied. One of these 7 patients had to undergo an additional open operative procedure. The results of the present study demonstrate that a majority of patients with calculi in the middle portion of the ureter can become stone-free without invasive lithotripsy techniques following ESWL in the prone position, if necessary plus auxiliary measures, in sedoanalgesia. From these results it can be concluded that primary ESWL in the prone position should be considered for patients with calculi in the middle third of the ureter before invasive lithotripsy techniques are applied.

Adult↗
PubMed1993

[Pneumoscrotum. Case report and review of the literature].

The rare case of a pneumopenis and pneumoscrotum after a thoracic operation is reported. Two subtypes--pneumatocele and subcutaneous emphysema of the scrotum--are differentiated on the basis of anatomy. The cases reported in the literature so far are reviewed. A therapeutic regimen is recommended.

Diagnosis, Differential↗
PubMed1992

M-VAC versus CisCA--chemotherapy in the treatment of advanced bladder cancer.

The results of this study do not demonstrate a superiority of M-VAC chemotherapy over a modified CisCA regimen chemotherapy. M-VAC, however, proved less toxic than CisCA in terms of side effects. Neither CisCA nor M-VAC was effective as a curative treatment for patients with distant metastases. A durable complete remission of 22.5 months was seen in only 2 of the 12 patients with locally advanced tumors without distant metastases treated with M-VAC, and one of 35 months was observed in only 1 of the 6 cases with locally advanced tumors treated with CisCA chemotherapy.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1992

[Urologic characteristics of 7 patients over 100 years of age].

In the last few decades the old old have increased continuously in numbers. Diseases of the genitourinary organs are a frequent part of the multiple morbidity we are familiar with in such patients. In the 9th decade of life the renal parenchyma is reduced by 30-50%. The decreased glomerular filtration combined with tubular insufficiency leads to disturbances of the electrolyte, water and acid-base balance. In contrast to these involutionary changes in the kidneys, the prostate increases in size owing to varying degrees of hyperplasia, and the incidence of malignant growth increases progressively. A total of 575 patients over the age of 100 years were observed at the Medical Policlinic of Würzburg University, and 7 of these who had pronounced urological disorders are described in detail. The variations in the ageing process are considerable. Urological illnesses in the course of the multiple morbidity usual in this group have a particularly unfavourable influence in the terminal phase of these old old patients.

Aged↗
PubMed1991

Radical prostatectomy for carcinoma of the prostate: long-term follow-up of 115 patients.

From July 1969 to September 1990, 370 patients with prostatic cancer underwent radical prostatectomy at our institution. Of these 370 patients, 115 consecutive patients could be followed for more than 10 years (mean 12.5). Patients with stage pT1-pT3 tumors received no further treatment until progression occurred. Patients with regional lymph node metastases (stages pT2-3pN1-2M0) were treated by either an immediate orchiectomy or an adjuvant hormonal therapy. No radiotherapy was applied prior to radical prostatectomy or thereafter. Of the 115 patients followed for more than 10 years, 84 had stage pT1-2, 22 had stage pT3, and 9 had stage pT2-3pN1-2 tumors. The observed 10-year survival rate of all 115 patients (including those with regional lymph node metastases) was found to be 67.0%. The 10-year disease-free survival rate was 58.3% and the tumor-related survival rate was 83.5%. Considering only patients with locally confined (stage pT1-2) tumors, the 10-year survival rate was 75.0%. This observed survival rate equals the 10-year survival expectancy of a male age-matched control population (69.9%). Progression (local recurrence or distant metastatic spread) was noted in 27.8% of patients within the 10-year interval after radical prostatectomy. Within this time interval, 16.5% of the patients died from their disease.

Adult↗
PubMed1991

Screening for prostatic cancer. The German experience.

The principles for screening for detection of early prostate cancer in the Federal Republic of Germany are described. Men are entitled from the beginning of their 45th year of life to an examination for early detection of cancerous diseases once annually and this examination is paid for by the insurance system. In the age group around 60 years about 15% of the men participate. Among 1,341,833 men participating in 1987, 1,638 new cases of prostate cancer were detected. The proportion of cases suitable for total prostatectomy has increased considerably since the screening program was introduced and now stands at about 25% in the author's department. The survival rate of this group is comparable to that of the general population, when adjusted for age distribution. It is suggested that screening for prostate cancer might reduce the mortality of this disease.

Germany, West↗
PubMed1991

[Selection criteria for radical prostatectomy with reference to long-term results].

Between July 1969 and May 1991 radical prostatectomies were performed in 410 consecutive patients with prostate cancer at the Department of Urology, University of Würzburg. The calculated survival rates for these 410 patients up to 15 years after surgery are very similar to the life expectancy of the normal male age-matched population. In 127 of the 410 cases radical prostatectomy was carried out more than 10 years ago, so that the data relating to these cases have been definitely observed, not merely statistically evaluated. In order to permit a comparison of our results with those reported in the literature, the TNM classification of 1979 was utilized in this study. This means that only tumors penetrating through the capsule of the prostate were classified as stage pT3. Those tumors that are only infiltrating the apex or the prostatic capsule, are classified as stage pT2. For patients with stage pT1pN0M0 and pT2pN0M0-tumors, 10-year survival rates (90.5% and 70% respectively) were recorded which are even slightly better than those of the normal male age-matched population. For patients with tumors extending through the capsule, the 10-year survival rate was found to be 60%. Forty percent ot these patients with stage pT3pN0M0 disease are alive tumor-free after more than 10 years and can thus be regarded as cured. When lymph node metastases were present (stage pT2-3pN1-2M0), some of the patients appeared to benefit from radical prostatectomy, since 4 out of 11 patients with this stage disease survived for more than 10 years.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1991

[Chemotherapy in metastasizing prostate carcinoma].

Seventeen patients with metastasized hormone-resistant prostate cancer were treated between January 1986 and October 1989 with combination chemotherapy at the Department of Urology, University of Würzburg Medical School. In 1 of the 17 patients a complete remission lasting 4 months was observed. In 3 patients a partial remission was noted, and in 5 others stable disease for an average of 6.8 months occurred. Tumor progression was seen in 7 patients. In all 16 evaluable cases palliation of tumor pain was achieved with this kind of treatment. The role of chemotherapy in the treatment of metastasized prostate cancer is discussed.

Aged↗
PubMed1991

[Ectopic splenic tissue in connection with the testis].

A case of ectopic splenic tissue in the testicle is reported. This congenital anomaly has only ever been seen in the left scrotal compartment. The ectopic splenic tissue is separated from the testicle by a fibrotic capsule. When accessory splenic tissue is suspected on examination of a testicular biopsy a frozen section should be performed; orchiectomy can then often be avoided.

Adult↗
PubMed1990

[Long-term results and histologic studies following surgical correction of congenital penis deviation].

Between 1982 and 1988, 11 patients with congenital penile curvature without hypospadia or chordee were operated according to the technique originally described by Nesbit. In all these patients the operative results were reevaluated after a period of 1 1/2 to 7 years (average 3 3/4 years). Normal sexual intercourse was possible for all 11 men, and good long-term cosmetic results were noted. In contrast to formerly published results, histological examination of the segments resected from the tunica albuginea showed fibrotic tissue in some cases, which could play an important role in the etiology and/or pathogenesis of congenital penile curvature.

Adolescent↗
PubMed1986

[Ureteral injuries in intervertebral lumbar disk surgery].

In lumbar disc surgery ureteral transection is a rare complication and only nine such cases have been reported so far. They are analyzed and two more cases are described. The complication in the first case was recognized immediately and the patient was treated successfully by end-to-end anastomosis of the ureter. The diagnosis in the second case was delayed and this lead to a septic course and finally required nephrectomy.

Adult↗
PubMed1985

[Transurethral punch resection of the prostate (cold punch). Results and complications].

In 1965 the cold punch technique of transurethral prostatic resection was introduced in Germany. The principal differences between the electroresectoscope and the punch resectoscope are explained. This report on the results and complications of cold punch resection of the prostate is based on 3030 patients who were operated upon by this technique. The average age was 71,6 years. 8,2% of the patients were 80 years or older. In 33,6% the operative risk was increased. Intraoperative, early and late complications of the procedure are reported. The mortality of 1,4% over the entire 20 year period was decreased to 0,65% for the last 10 years.

Aged↗
PubMed1985

[Complications of radical prostatectomy].

Between 1969 and 1984 a radical prostatectomy was performed in 175 patients for localized carcinoma of the prostate. This corresponds to a percentage of 18,2% of 962 patients with cancer of the prostate admitted to this hospital during the same period of time. The intra- and postoperative complications following radical prostatectomy in this series of 175 patients are analyzed. In 144 patients a retropubic prostatectomy was performed, whereas in 31 patients the perineal approach was utilized. There was a mortality rate of 1.1% (2 patients). Rectal injuries in 7 patients and ureteral transsection in 2 patients accounted for intraoperative complications. In the early postoperative period non-fatal pulmonary embolism occurred in 4 and myocardial infarction in 3 patients. In 3 cases (1,7%) a transitory hemodialysis became necessary because of renal insufficiency. Lymphoceles had to be treated in 22 patients (12,6%) and hematomas in 9 patients (5,1%). Persistent total urinary incontinence was observed in 8 patients (5%) and stress incontinence of varying degree in 25% of cases. The causes of these complications are analyzed and possible ways of preventing and treating them are discussed.

Adult↗