Biomedical subjects

H G Doerr

Publications and source records attributed to H G Doerr.

21 records · Page 2Linked to original sources

PubMed1982

Dexamethasone suppression of 11-deoxycorticosterone, corticosterone and cortisol in depressed female patients and normal controls.

The dexamethasone suppression test based upon analysis of 11-deoxycorticosterone, corticosterone and cortisol was applied to 20 female depressed patients (10 endogenous, 10 neurotic) and 10 healthy controls. Calculating ratios of corticosterone to its biological precursor 11-deoxycorticosterone allows to assess the activity of adrenal 11 beta-hydroxylase. This enzyme activity depends on the mean secretion rate of ACTH. The preliminary data indicate that the sensitivity of the test may be increased when based on this enzyme activity rather than upon plasma cortisol concentrations. The decrease of 11-deoxycorticosterone, a potent mineralocorticoid in relation to corticosterone may contribute to the reduced urine concentrating capacity in patients with endogenous depression.

Adult↗

PubMedDate not supplied

Observations of reported and measured heights of mothers of short statured children.

A study was performed in which mothers of normal variant short statured children (n=37), were asked to state their own height. Then their body height was measured with a Harpenden Stadiometer. As control group, mothers of normal statured children (n=54) who were presented for various reasons (e.g. obesity, goiter) underwent the same procedure. The results show that the estimations are not reliable in short mothers with short statured children, whereas the control group showed no significant differences between reported and measured heights. There was a direct significant negative correlation (r=0.624; p < 0.001) between reported and measured heights in women with short children. The smaller the woman, the higher the reported height.

Adult↗

PubMedDate not supplied

A boy presenting with familial short stature--diagnosis Gitelman syndrome.

Patients with Gitelman syndrome are usually diagnosed by chance or present with muscular weakness, constipation, or tetanies due to hypokalemia and hypomagnesemia. We present a short statured boy with a clear history of familial short stature, normal growth and a final height prognosis within the target height range. However, routine laboratory studies led to the diagnosis of Gitelman syndrome. If a baseline laboratory analysis had not been performed, this diagnosis would have been missed.

Body Height↗