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Biomedical subjects

H G Kemp

Publications and source records attributed to H G Kemp.

10 recordsLinked to original sources

Percutaneous transluminal coronary angioplasty in New York State. Risk factors and outcomes.

OBJECTIVE: To identify significant independent risk factors for major percutaneous transluminal coronary angioplasty outcomes. DESIGN: Retrospective analysis using univariate and logistic regression analysis to identify significant independent risk factors for adverse outcomes. SETTING: All 31 hospitals performing percutaneous transluminal coronary angioplasty in New York State in 1991. PATIENTS: All 5827 patients undergoing percutaneous transluminal coronary angioplasty between January 1, 1991, and June 30, 1991, in New York State. MAIN OUTCOME MEASURES: In-hospital mortality, major complication(s) (in-hospital mortality, myocardial infarction, and/or emergency coronary artery bypass graft), and absence of angiographic success (stenosis reduction of less than 20% on any attempted lesion or residual stenosis of at least 50% on any attempted lesion). MAIN RESULTS: Before discharge from the hospital, a total of 37 patients (0.63%) died; 67 patients (1.1%) suffered a myocardial infarction, with a mortality rate of 4.5%; and 97 patients (1.7%) underwent emergency coronary artery bypass graft surgery, with a mortality rate of 2.1% (no deaths in 85 patients who were hemodynamically stable and two deaths among 12 patients who were hemodynamically unstable). A total of 187 patients (3.2%) experienced a major complication. Angiographic success was achieved for 88% of all patients. Multivariate analysis found four independent preprocedural variables related to death: female gender, hemodynamic instability, shock, and ejection fraction. CONCLUSIONS: Percutaneous transluminal coronary angioplasty outcomes in New York compare favorably with other recent results reported in the literature. Several preprocedural variables markedly increase the incidence of adverse events.

Aged

Asynchronous ventricular relaxation: an angiographic temporal analysis of asynchronous left ventricular relaxation in man.

Segmental "early relaxation" is a common angiographic finding. An attempt was made to elucidate the temporal characteristics of this event. Twenty subjects with and 20 without segmental early relaxation were studied. The left ventricular diastolic relaxation time was precisely determined angiographically, and the findings were as follows: 0.12 +/- 0.04 second (mean +/- standard deviation) in the normal patients, 0.14 +/- 0.03 second in the patients with coronary artery disease but no segmental early relaxation and 0.20 +/- 0.04 second in the patients with segmental early relaxation. These findings indicate that early relaxation is associated with a significantly prolonged ventricular relaxation time. The use of the term asynchronous ventricular relaxation is proposed to denote the disturbed diastolic properties of the ventricle with "early relaxation."

Angiocardiography

Complications of coronary arteriography from the Collaborative Study of Coronary Artery Surgery (CASS).

Data were collected prospectively on 7553 consecutive patients undergoing coronary arteriography. The studies were performed at 13 clinics of the Collaborative Study of Coronary Artery Surgery (CASS) using brachial and femoral techniques. There were eight deaths 0--24 hours and seven deaths 24--48 hours after arteriography (2/1000). There were 15 non-fatal myocardial infarctions (MIs) 0--24 hours and four MIs 24--48 hours after arteriography (2.5/1000). Of 657 cases with left main stenosis greater than or equal to 50%, five died and three had MI. Left main disease increased risk of death by 6.8 times (p less than 0.001). Other factors increasing risk were unstable angina, congestive heart failure, multiple premature ventricular contractions, and hypertension. Of the 1187 patients studied from the brachial artery, six died (0.51%) and five had MIs (0.42%). In 6328 patients studied from the femoral artery, nine died (0.14%) and 14 had MIs (0.22%). The brachial artery technique increased the risk of death 3.6 times compared with the femoral approach (p less than 0.05). This result did not apply when analysis was restricted to laboratories with 80% or more brachial procedures. Risk was not altered by heparin. Thus, a prospective, multicenter analysis of complications reveals low risk of coronary arteriography but significant difference between two techniques.

Adult

Aortocoronary bypass surgery: a 7-year follow-up.

Follow-up of 748 consecutive patients who underwent aortocoronary artery bypass grafts was obtained for 5 to 94 months (average, 59 months). Operative mortality of 2.5% did not vary with number of vessels bypassed. There was a linear 3.5% annual recurrence rate of angina, and average annual late infarction rate of 1.4%. The cumulative survival rates did not differ for the number of grafts performed or for men and women, but did differ for left main coronary stenosis and impaired ejection fractions. The late cumulative survival rates for the entire group approached those of the general U.S. population.

Adult

Radiocardiography in clinical cardiology.

Quantitative radiocardiography provides a variety of noninvasive measurements of value in cardiology. A gamma camera and computer processing are required for most of these measurements. The advantages of ease, economy, and safety of these procedures are, in part, offset by the complexity of as yet unstandaridized methods and incomplete validation of results. The expansion of these techniques will inevitably be rapid. Their careful performance requires, for the moment, a major and perhaps dedicated effort by at least one member of the professional team, if the pitfalls that lead to unrecognized error are to be avoided. We may anticipate more automated and reliable results with increased experience and validation.

Heart Aneurysm

Left internal mammary artery--coronary artery bypass anatomy.

Bypass coronary surgery has made good use of the anatomic proximity of the internal mammary artery and the left anterior descending coronary artery. In preparing the internal mammary artery for bypass surgery, several of its proximal branches remain intact and are visualized during selective studies of the bypass graft. A brief description of these vessels is presented with specific attention to the branching and position of the pericardial vessels and their relationship to the grafted left anterior descending artery.

Internal Mammary-Coronary Artery Anastomosis

Radiographic visualization of left ventricular aneurysms on lateral chest film.

The diagnosis of left ventricular aneurysm on routine chest examination can be elusive. Six cases are presented which illustrate a radiographic sign not previously emphasized: a soft tissue border seen retrosternally or superiorly on lateral chest film produced by the wall of the aneurysm silhouetting against the midline cardiac shadow. This sign is not always present since it is dependent on the direction of projection of the aneurysm. However, when observed, it should suggest the proper diagnosis.

Adult