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H G Knauff

Publications and source records attributed to H G Knauff.

18 recordsLinked to original sources

[Effect of parenteral amino acid administration on the brain function and the serum aminogram of patients with liver cirrhosis].

10 patients with cirrhosis of the liver, 5 with hepatic encephalopathy, were treated by infusion therapy with an amino acid solution adapted to the metabolic conditions seen in hepatic insufficiency. In all cases the amino acid imbalance improved. In 11 episodes of hepatic coma, changes in the pattern of serum amino acids always were accompanied by a marked decrease of elevated ammonia levels and a restitution of clear consciousness. This clinical improvement developed rather rapidly and could be objectivated impressively by psychometric tests.

Adult↗

[Use of different parenterally administered amino acid solutions with healthy test subjects].

We studied the alterations in the pattern of free serum amino acids during continuous parenteral infusion of 4 different standardised L-amino acid solutions. Nearly for all amino acids, a dose-dependent steady state could be established, usually as early as 30 or 60 minutes after starting the infusion. Amino acid solutions that caused the smallest changes of the amino acid pattern in plasma during infusion produced always the smallest increase of total amino acid nitrogen and the greatest rate of amino acid transfer. So we conclude that these solutions are utilised most effectively.

Adult↗