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Biomedical subjects

H G Kwee

Publications and source records attributed to H G Kwee.

5 recordsLinked to original sources

Fibrolamellar hepatocellular carcinoma.

Fibrolamellar hepatocellular carcinoma is a primary malignant tumor of the liver that usually affects adolescents and young adults. If detected early, this cancer is frequently resectable, with a much longer survival time than in classic hepatocellular carcinoma. Fibrolamellar hepatocellular carcinoma has distinct radiographic and pathologic features. Serum unsaturated vitamin B12 binding capacity and plasma neurotensin may be used as tumor markers.

Adult↗

Anisakiasis.

Larval forms of nematodes of the Anisakidae family (cod or herring worms) can cause disease in people who eat raw or undercooked seafood. These nematodes are widespread along the eastern and western coasts of the United States, and the larvae can be found in fresh fish sold in any grocery store. Luminal infestation causes few symptoms. Invasive anisakiasis may be acute or chronic and may involve the stomach or the small intestine.

Acute Disease↗

A racial difference in serum vitamin B12 levels.

Measurements of the serum Vitamin B12 concentrations of 49 black and 49 white healthy adults demonstrate a significantly higher mean serum Vitamin B12 level in blacks when compared to whites (p less than 0.001). The reason for this difference appears to be genetic, although environmental factors may also be involved. It is suggested that clinical laboratories should establish their own separate reference values of serum Vitamin B12 for blacks and whites in order to prevent misinterpretation of test results.

Adult↗

Radionuclide imaging of experimental myocarditis.

The ability of 67Ga citrate and 99mTc pyrophosphate cardiac imaging to detect myocarditis was assessed in an experimental rabbit model. Twenty-three rabbits were imaged approximately 72 hours after infusion of i.v. norepinephrine. Diffuse cardiac uptake was found in 13 of 15 rabbits scanned with 67Ga. Tissue distribution studies documented significant myocardial uptake of 67Ga in those with positive scans. Precordial imaging and tissue distribution studies revealed no cardiac uptake in the eight rabbits scanned with 99mTc. Histologic examination of all 23 hearts revealed qualitatively similar, typical lesions of myocarditis. This study suggests that cardiac imaging with 67Ga may be useful in the detection of myocarditis.

Animals↗