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Biomedical subjects

H G Robert

Publications and source records attributed to H G Robert.

At least 19 recordsLinked to original sources
PubMed1983

[Superoxide dismutase treatment of 2 cases of radiation-induced sclerosis].

Two patients with severe radio-induced necrosis were treated with bovine copper superoxide dismutase encapsulated in lysosomes (SOD). Two milligrams were injected subcutaneously every other day. This therapy was apparently effective on radio-induced inflammation and fibrosis. These are preliminary results that need confirmation. They suggest that SOD is useful, not only before radiation exposure, as a preventive, but also after exposure, as curative treatment for radiation injury.

Aged↗
PubMed1980

[Genital prolapse in elderly women (150 cases) (author's transl)].

A series of 150 operations, by the same surgeon, for genital prolapse in women over 60 years of age (range to 85 years), represented 36% of the total number of operations for prolapse performed. A total of 32 women had had previous prolapse operations, 24 developed prolapse after hysterectomy, and 11 had postoperative colpoceles. This means that 45% had iatrogenic lesions, term in fashion at the present time but which strongly emphasizes the role played by insufficiently defined operative indications, and operations conducted without sufficient rigour. The most frequent lesions, were firstly cystoceles, then external prolapses, followed by hysteroceles. Urinary incontinence was evident in 15%, and potential in at least 10% of continent women. The lower approach was employed for the operation, either obturating or conservative, in most cases. When the upper approach was used, this was mainly for pathogenic purposes, and adapted to the lesion. Overall results were excellent, and only two irreversible accidents occurred. Recurrences were mainly in the form of cystoceles, micturition disorders, or sometimes rectocele sequelae. Increased life-span and improved operative treatment should make the surgery of prolapse in elderly women even more effective.

Aged↗
PubMed1978

[Tubal sterility: Disturbances in haemostasis and cardiac arrest during the shirodkar manoeuvre (author's transl)].

Over a period of 10 months (august 1975 to may 1976), the authors observed 6 successive accidents during the Shirodkar manoeuvre during operations for sterility of tubal origin: 1) 4 cases involved disturbances in haemostasis only, clinical manifestations being seen in only one case. In the laboratory, these quite atypical manifestations suggested either fibrinolysis or disseminated intravascular coagulation. 2) In 2 cases there was cardiovascular collapse with cardiac arrest. In the first patient, cardiac arrest was followed by a period of coagulopathy quite similar to those seen previously. In the second case resuscitation failed, leading the authors to abandon use of the Shirodkar manoeuvre, which brought the study to an end. We are unable to provide any satisfactory pathological interpretation of these complications, thought two factors are worthy of consideration:--The hydrocortisone suspension used;--The uterine trauma related to peroperative manipulations.

Blood Coagulation Disorders↗
PubMed1976

[Thecal tumors of the ovary. 14 cases].

Out of 524 tumours of the ovary seen over a 20 year period, the diagnosis was that of a thecal tumour in 14 cases. In addition to the symptoms common to all ovarian tumours, in 7 cases there was metrorrhagia, including 4 post-menopausal. Vaginal cytology after the menopause was abnormally young in 6 cases. In 7 cases out of 13 the endometrium was hyperplasic. In only 5 cases were urinary oestrogen levels increased. At operation, the tumour was bilateral in 3 cases and ascites was present in 4. Histological findings were as follows: 6 thecomas, 4 fibro-thecomas, 1 luteinised thecal tumour, 3 tumours with granular cells and 1 case associated with a Brenner tumour. Two of these "mixed tumours" were malignant, with a fatal outcome. All the others were cured by operation. In young women in whom conservative procedures were used there were 4 subsequent pregnancies. The following questions were posed: The coexistence of ascites with tumours totally free of secretory cells (3 cases); The existence in true thecal tumours of signs of hyperoestrogenism (5 out of 6) whilst fibro-thecomas are not associated with any abnormal production of oestrogen.

Adolescent↗
PubMedDate not supplied

[Ureter and Wertheim's operation].

The surgery for carcinoma of the uterine cervix combined with radiotherapy, as carried out at present, includes a definite risk for the urinary tract. Not so much the immediate functional disorders, which always recede, except in rare cases of fibrous retracted bladder, but the lesions which occur in several varieties lead one to re-implant immediately the ureter. Fistulae and early stenosis (16 out of 1,500) should be treated in the same way. These late complications, such as obstruction (12 out of 1,500) raise de problem of their etiology. Usually they are due to recurrent carcinoma (9 out of 12), rarely due to pelvic fibrosis (3 out of 12). It is rare then for re-implantation to be possible. There remains either nephrectomy which is the simplest solution, or an urinary by-pass operation either using an ileal bladder or as a palliative measure, using a silastic prosthesis. Finally, the risk of advanced carconoma is without remedy, abstention from surgery may then be justified but one should, as far as possible, attempt to prevent these complications both from the surgical technical point of view and from the point of view of irradiation dosage.

Dermatologic Surgical Procedures↗