Two cases of short bowel syndrome taking restricted oral diet: still candidates for intestinal transplantation?
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Biomedical subjects
Publications and source records attributed to H Gündoğdu.
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Although extensive research has been carried out on the respiratory and renal effects of intra-abdominal pressure increase, there is limited research with regard to its effects on bacterial translocation. The objective of this study was to discuss whether the high intra-abdominal pressure due to carbon dioxide (CO2) insufflation during laparoscopy leads to bacterial translocation. Eighteen male dogs, 7 of which constituted the control group, were used in the study. Two study groups, in which the intra-abdominal pressure was raised to 15 mm Hg and kept at that level for 30 and 120 minutes, respectively, were set. Blood gases and blood pressure values were observed throughout the experiments. Samples of peritoneal smear, portal vein blood, mesenteric lymph node, liver, spleen, and cecum were examined to detect bacterial translocation. Histopathological examinations of all samples were also carried out. No translocation was detected in the samples of peritoneal smear, portal blood, mesenteric lymph node, liver, or spleen, but in the samples of cecum, bacterial colonization for the second group (p<0.05) and for the third group (p<0.05) was significantly higher compared with the control group. There was a considerable difference between the second and third groups (p<0.05). The changes in the mesenteric lymph nodes were interpreted to be a result of bacterial drainage. Histopathological examination disclosed active changes in the mesenteric lymph nodes in all groups, but there was considerable sinus histiocytosis only in the third group. We conclude that the intraabdominal pressure of 15 mm Hg created by carbon dioxide insufflation does not lead to bacterial translocation but causes intraluminal bacterial colonization in the cecum after 30 minutes and after 2 hours.
Primary realignment was used in the treatment of 12 children with complete rupture of the posterior urethra; 10 developed strictures but 7 of these responded to dilation. Problems of continence were encountered only in patients who developed strictures. Since primary realignment results in dilatable strictures in most patients, it is suggested that this should be the treatment of choice in children.
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Mesenteric and omental cysts are infrequently encountered, benign, intraabdominal tumors. Nineteen new patients were analysed. The most common presenting symptoms were abdominal distension (74%) and abdominal pain (63%). A palpable abdominal mass was found in 58 percent of cases. A correct preoperative diagnosis was established in 91 percent of the patients who were examined by abdominal ultrasonography. Of 19 cases documented at laparotomy, 14 patients (74%) had mesenteric, and five patients (26%) omental cysts. Eleven of the former were located in the small bowel mesentery. All of the cysts were completely removed, and in eight of them bowel resection was required. Subtotal gastrectomy was performed in one case. The mortality rate was 0%. After a mean follow-up period of five years, no recurrence was observed. Our study showed that abdominal ultrasonography by experienced professionals is the most reliable diagnostic tool for detecting these lesions.