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Biomedical subjects

H Günter

Publications and source records attributed to H Günter.

10 recordsLinked to original sources

[Pregnancies following kidney transplantation and in immunosuppression with cyclosporin A].

From 1984 to 1987, offspring from six renal transplant-patients were delivered in the Department of Obstetrics and Gynaecology of the Medical School of Hannover. The patients received cyclosporine and cortisone as an immunosuppressive therapy during the pregnancies. All pregnancies ended with live births; in two cases, a caesarean section was performed. Serious congenital malformations of the newborns were not observed, only two newborns being small. In the blood of the newborns, the cyclosporine concentrations were between 85 and 65% of the maternal blood levels. In two patients, the kidney functions deteriorated significantly during and after pregnancy. An increase in blood pressure or a hypertonic crisis, however, did not occur.

Adult

[Detection of cyclosporin A in breast milk--is breast feeding contraindicated?].

Cyclosporin A (CyA) was measured simultaneous in breast milk and maternal and fetal blood with a new monoclonal specific radioimmunoassay in a patient who was treated with Cyclosporin A during pregnancy because of kidney transplantation. CyA-levels in breast milk were 15 to 90% higher than in maternal blood. In case of breast feeding a child would take up less than 5 percent of an immunosuppressive dose. However, we would recommend ablactation because of the toxicity and the unknown side effects of CyA for the child's immunologic system.

Adult

[Application of laser rays in surgery (author's transl)].

Some years will have to pass, until there will be evidence, if the application of laser beam in surgery of breastcancer, melanomas or basaliomas will be justified and whether it will be possible or not to interrupt or reduce intraoperative tumor cellspread. As an increasing number of surgeons have started to use laser rays in these cases of illness, results of laser surgery and those of tradional methods could be compared in a couple of years. Possibly other indications for the use of laser than those we have worked out will be outlined in general surgery. Surgeons working with laser beam may discredit the method by putting the indication not rigorusly enough. Greatest care should be taken by everybody who starts working with laser rays. Collaboration with a technician is recommended.

Breast Diseases

[Application of laser rays in surgery (author's transl)].

Some years will have to pass, until there will be evidence, if application of leaser beam in surgery of Breastcancer, Melanomas or Basaliomas was justified and whether it is possible or not to interrupt or reduce intraoperative tumor cellspread. As an increasing number of surgeons have started to use laser rays in these illnesses, result of laser surgery and those of traditional methods could be compared in a couple of years. Possibly other indications will be outlined in general surgery for the use of laser beside those we have been working out. It may happen that surgeons working with laser beam might bring the method into discredit putting indication not rigorous enough. I should like to remind everybody who starts working with laser rays, to do so with greatest possible care. Collaboration with a technician is recommended. Periodic he should control the machine and handle arising technical problems.

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