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H GAY

Publications and source records attributed to H GAY.

15 recordsLinked to original sources
PubMed1964

HISTONE PROTEIN TRANSITION IN DROSOPHILA MELANOGASTER. II. CHANGES DURING EARLY EMBRYONIC DEVELOPMENT.

Employing cytochemical methods it was found that during the early embryonic development of Drosophila melanogaster the nuclei contain in sequence two kinds of chromosomal proteins. The cleavage nuclei (as also the pronuclei), until shortly before the blastoderm stage, contain an atypical (or juvenile) histone, stainable with bromophenol blue but not with alkaline fast green. The typical fast green-positive histone appears at the close of the period of the synchronized cleavage mitoses, just before blastulation, when nucleoli are first produced. The amount of DNA of the cleavage nuclei, as determined cytophotometrically, is nearly constant; therefore, the DNA moiety of the nucleohistone complex seems to remain unaffected by the protein shift during embryonic development. The implications of the protein shift in relation to the histone control of gene expression are discussed.

Animals↗
PubMed1956

Chromosome-nuclear membrane-cytoplasmic interrelations in Drosophila.

The structural evidence for nucleocytoplasmic interrelationships observed in electron micrographs of salivary-gland cells of third instar larvae of Drosophila melanogaster has been reviewed. It has been found that the characteristic nuclear membrane outpocketings with their adjacent highly differentiated chromosomal materials occur at one stage of larval development at a time when a new cellular function is being initiated. Preliminary cytochemical studies to characterize the materials transferred from nucleus to cytoplasm indicate that deoxyribonucleic acid occurs within the blebs. Observations on chromosome and nuclear membrane structure are also presented.

Animals↗